Ventura, F; Antunes, H; Brito, C; Pardal, F; Pereira, T; Vieira, AP
Precioso, J; Calheiros, JM; Pereira, D; Campos, H; Antunes, H; Rebelo, L; Bonito, J
Tobacco smoking is the cause of more than half million deaths/year in the European Union (EU). Monitoring smoking prevalence is an important tool to evaluate the epidemic and its evolution and to assess the effectiveness of preventive measures. The comparison between countries may help us identify good control practices.
To describe the current state and evolution of the smoking epidemic in several EU countries, and to characterize the Portuguese situation in comparison with those countries.
To characterize smoking habits and their evolution in the population over 15 years old, several Eurobarometer reports from 1995 to 2007 were used. The characterization of School...
Precioso, J; Samorinha, C; Calheiros, JM; Macedo, M; Antunes, H; Campos, H
To evaluate the effectiveness of the preventative programme "Smoke-free Homes" undertaken in 4th year children and their parents or guardians, aiming to reduce children's exposure to second hand smoke (SHS) in the home.
MATERIAL AND METHODS:
This was a pre- and post-test pre-experimental study, in students from 32 Braga district primary schools 2007/08. A self-administered and structured questionnaire was given out to 795 students in the classroom before and after the programme. In analysing data, we used the chi-squared test for the categorical variables.
The rate of children exposed to regular or occasional SHS due to living with at least one smoker dropped...
Neiva, F; Martins, S; Castro-Correia, C; Costa, C; Leão, M; Fontoura, M
A baixa estatura afecta cerca de 2% das crianças e representa um dos motivos mais frequentes da consulta de Endocrinologia Pediátrica. A heterogeneidade genética responsável pela baixa estatura sofreu um grande avanço com a descrição do gene SHOX ('short stature homeobox containing gene'). A proteína codificada localiza-se exclusivamente no núcleo de algumas células, e está envolvida na regulação do desenvolvimento, diferenciação e organogénese, com uma expressão limitada no espaço e no tempo. A expressão fenotípica é variável, com mais de 50 mutações do gene descritas. Mutações heterozigóticas do gene SHOX foram relatadas em casos de síndrome de Léri-Weill (SLW). Descreve-se...
Antunes, H; Rodrigues, H; Silva, N; Ferreira, C; Carvalho, F; Ramalho, H; Gonçalves, A; Branca, F
BACKGROUND: In 2006, bronchiolitis due to adenovirus nosocomial infections resulted in the closure of a pediatric department in northern Portugal.
OBJECTIVES: To determine the etiology of bronchiolitis in northern Portugal.
STUDY DESIGN: It was a prospective multicenter study on the etiology of bronchiolitis during the respiratory syncytial virus (RSV) season (November-April). Children < or = 24 months of age admitted for a first wheezing episode were included. Nasopharyngeal specimens were analyzed by an indirect immunofluorescent-antibody assay (IFA) for RSV, adenovirus (HAdV), parainfluenza (PIV) 1-3 and influenza (IV) A and B and by polymerase chain reaction (PCR) or reverse transcription-PCR for the same...
Antunes, H; Rocha, R; Silva, N; Pontes, T; Antunes, A; Martins, S
We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy.The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.