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rss_1.0 Recursos de colección

PubMed Central (PMC3 - NLM DTD) (2.636.741 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).

Clinical Epigenetics

Mostrando recursos 1 - 20 de 90

1. Differences in smoking associated DNA methylation patterns in South Asians and Europeans - Elliott, Hannah R; Tillin, Therese; McArdle, Wendy L; Ho, Karen; Duggirala, Aparna; Frayling, Tim M; Davey Smith, George; Hughes, Alun D; Chaturvedi, Nish; Relton, Caroline L

2. Reviewer Acknowledgement 2014 - Mahlknecht, Ulrich

3. The effects of olanzapine on genome-wide DNA methylation in the hippocampus and cerebellum - Melka, Melkaye G; Laufer, Benjamin I; McDonald, Patrick; Castellani, Christina A; Rajakumar, Nagalingam; O’Reilly, Richard; Singh, Shiva M

4. Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors - Stewart, David J; Nunez, Maria I; Jelinek, Jaroslav; Hong, David; Gupta, Sanjay; Issa, Jean-Pierre; Wistuba, Ignacio I; Kurzrock, Razelle

5. Epimutation profiling in Beckwith-Wiedemann syndrome: relationship with assisted reproductive technology - Tee, Louise; Lim, Derek HK; Dias, Renuka P; Baudement, Marie-Odile; Slater, Amy A; Kirby, Gail; Hancocks, Tom; Stewart, Helen; Hardy, Carol; Macdonald, Fiona; Maher, Eamonn R

6. Maintaining the unmethylated state - Smith, Steven S

7. Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma - Ricketts, Christopher J; Morris, Mark R; Gentle, Dean; Shuib, Salwati; Brown, Michael; Clarke, Noel; Wei, Wenbin; Nathan, Paul; Latif, Farida; Maher, Eamonn R

8. Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men - Gu, Tianwei; Gu, Harvest F; Hilding, Agneta; Sjöholm, Louise K; Östenson, Claes-Göran; Ekström, Tomas J; Brismar, Kerstin

9. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking - Philibert, Robert A; Beach, Steven R H; Lei, Man-Kit; Brody, Gene H

10. Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes - Gu, Harvest F; Gu, Tianwei; Hilding, Agneta; Zhu, Yiming; Kärvestedt, Lars; Östenson, Claes-Göran; Lai, Maode; Kutsukake, Masahiko; Frystyk, Jan; Tamura, Kazuhiro; Brismar, Kerstin

11. Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders - Stringer, Randa L; Laufer, Benjamin I; Kleiber, Morgan L; Singh, Shiva M

12. Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents - Fredly, Hanne; Gjertsen, Bjørn Tore; Bruserud, Øystein
Several new therapeutic strategies are now considered for acute myeloid leukemia (AML) patients unfit for intensive chemotherapy, including modulation of protein lysine acetylation through inhibition of histone deacetylases (HDACs). These enzymes alter the acetylation of several proteins, including histones and transcription factors, as well as several other proteins directly involved in the regulation of cell proliferation, differentiation and apoptosis. Valproic acid (VPA) is a HDAC inhibitor that has been investigated in several clinical AML studies, usually in combination with all-trans retinoic acid (ATRA) for treatment of patients unfit for intensive chemotherapy, for example older patients, and many of these patients...

13. Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1 - Katto, Judith; Engel, Nicole; Abbas, Wasim; Herbein, Georges; Mahlknecht, Ulrich

14. Specific inhibition of one DNMT1-including complex influences tumor initiation and progression - Cheray, Mathilde; Pacaud, Romain; Nadaradjane, Arulraj; Vallette, François M; Cartron, Pierre-François

15. Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis - Wendling, Daniel; Abbas, Wasim; Godfrin-Valnet, Marie; Guillot, Xavier; Khan, Kashif Aziz; Cedoz, Jean-Pierre; Baud, Lucile; Prati, Clément; Herbein, Georges

16. Tissue-specific DNA methylation profiles in newborns - Herzog, Emilie; Galvez, Jubby; Roks, Anton; Stolk, Lisette; Verbiest, Michael; Eilers, Paul; Cornelissen, Jan; Steegers, Eric; Steegers-Theunissen, Régine

17. DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population - Kullmann, Kathrin; Deryal, Mustafa; Ong, Mei Fang; Schmidt, Werner; Mahlknecht, Ulrich

18. Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia - Sundrani, Deepali P; Reddy, Umakar S; Joshi, Asmita A; Mehendale, Savita S; Chavan-Gautam, Preeti M; Hardikar, Anandwardhan A; Chandak, Giriraj R; Joshi, Sadhana R

19. Variation in ultraviolet radiation and diabetes: evidence of an epigenetic effect that modulates diabetics’ lifespan - Davis, George E; Lowell, Walter E

20. Reviewer acknowledgement 2013 - Mahlknecht, Ulrich

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