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Caltech Authors (14.256 recursos)
Repository of works by Caltech published authors.

Mostrando recursos 1 - 18 de 18

1. Kinetics of phase transformations in the peridynamic formulation of continuum mechanics - Dayal, Kaushik; Bhattacharya, Kaushik
We study the kinetics of phase transformations in solids using the peridynamic formulation of continuum mechanics.

2. Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks - Hart, Christopher Edward; Mjolsness, Erik; Wold, Barbara J.
Comparative analysis of motif binding sites among multiple sensu stricto yeast species independently confirmed relationships in the ANN weights analysis.

3. WormBook: the online review of Caenorhabditis elegans biology - Girard, Lisa R.; Fiedler, Tristan J.; Harris, Todd W.; Carvalho, Felicia; Antoshechkin, Igor; Han, Michael; Sternberg, Paul W.; Stein, Lincoln D.; Chalfie, Martin
WormBook (www.wormbook.org) is an open-access, online collection of original, peer-reviewed chapters on the biology of Caenorhabditis elegans and related nematodes.

4. The Drosophila IAP DIAP2 is dispensable for cell survival, required for the innate immune response to Gram-negative bacterial infection, and can be negatively regulated by the Reaper/Hid/Grim family of IAP-binding apoptosis inducers - Huh, Jun R.; Foe, Ian; Muro, Israel; Chen, Chun Hong; Seol, Jae Hong; Yoo, Soon Ji; Guo, Ming; Park, Jin Mo; Hay, Bruce A.
A second Drosophila IAP, DIAP2, also binds Rpr and Hid, and inhibits apoptosis in multiple contexts when overexpressed.

5. Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone - Hawkins, Andrew C.; Arnold, Frances H.; Stuermer, Rainer; Hauer, Bernhard; Leadbetter, Jared R.
LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL) dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum sensing system of Vibrio fischeri.

6. Conformational variability of the glycine receptor M2 domain in response to activation by different agonists - Pless, Stephan A.; Dibas, Mohammed I.; Lester, Henry A.; Lynch, Joseph W.
Conformational flexibility was assessed by tethering a rhodamine fluorophore to cysteines introduced at the 19’ or 22’ positions and monitoring fluorescence and current changes during channel activation.

7. Probing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prions - Dong, Jijun; Bloom, Jesse D.; Goncharov, Vladimir; Chattopadhyay, Madhuri; Millhauser, Glenn L.; Lynn, David G.; Schiebel, Thomas; Lindquist, Susan
Oligopeptide repeats appear in many proteins that undergo conformational conversions to form amyloid, including the mammalian prion protein PrP and the yeast prion protein Sup35.

8. Cellular expression and crystal structure of the murine cytomegalovirus MHC-Iv glycoprotein, m153 - Mans, Janet; Natarajan, Kannan; Balbo, Andrea; Schuck, Peter; Eikel, Daniel; Hess, Sonja; Robinson, Howard; Šimi?, Hrvoje; Jonji?, Stipan; Tiemessen, Caroline T.; Margulies, David H.
MCMV encodes the m145 family of putative immunoevasins with predicted MHC-I structure.

9. Mechanisms of base selection by the E.coli mispaired uracil glycosylase, MUG - Liu, Pingfang; Theruvathu, Jacob A.; Darwanto, Agus; Valinluck Lao, Victoria; Pascal, Tod; Goddard, William, III; Sowers, Lawrence C.
The repair of the multitude of single-base lesions formed daily in the cells of all living organisms is accomplished primarily by the base-excision repair (BER) pathway that initiates repair through a series of lesion-selective glycosylases.

10. Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plamsa membrane - Zhang, An-Sheng; Yang, Fan; Meyer, Kathrin; Hernandez, Catalina; Chapman-Arvedson, Tara; Bjorkman, Pamela J.; Enns, Caroline A.
Its encoded protein, hemojuvelin (HJV), is a co-receptor for the bone morphogenetic proteins 2 and 4 (BMP2 and BMP4) and enhances the BMP-induced hepcidin expression.

11. Signaling and crosstalk by C5a and UDP in macrophages selectively use PLCbeta 3 to regulate intracellular free calcium - Roach, Tamara I. A.; Rebres, Robert A.; Fraser, Iain D. C.; DeCamp, Dianne L.; Lin, Keng-Mean; Sternweis, Paul C.; Simon, Mel I.; Seaman, William E.
C5a and UDP synergized in generating inositol-1,4,5-trisphosphate, suggesting synergy in activating phospholipase C (PLC) ß.

12. Lattice thermal conductivity of self-assembled PbTe-Sb2Te3 composites with nanometer lamellae - Ikeda, Teruyuki; Toberer, Eric S,; Ravi, Vilupanur; Haile, Sossina; Snyder, G. Jeffrey
It has been reported that this compound is decomposed into the two immiscible thermoelectric materials forming nanosized lamellar structure by heat treatments.

13. Processing of G4 DNA by Dna2 Helicase/nuclease and RPA provides insights into the mechanism of Dna2/RPA substrate recognition - Masuda-Sasa, Taro; Polaczek, Piotr; Peng, Xiao P.; Chen, Lu; Campbell, Judith L.

14. Core binding factors are necessary for natural killer cell development, and cooperate with Notch signaling during T cell specification - Guo, Yalin; Maillard, Ivan; Chakraborti, Sankhamala; Rothenberg, Ellen V.; Speck, Nancy A.
CBF{beta} is the non-DNA binding subunit of the core binding factors (CBFs).

15. Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII - Jiang, Lily I.; Collins, Julie; Davis, Richard; Fraser, Iain D.; Sternweis, Paul C.
Regulation of intracellular cyclic adenosine 3’, 5’-monophosphate (cAMP) by multiple pathways enables differential function of this ubiquitous second messenger in a context dependent manner.

16. Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway - Xia, Zanxian; Webster, Ailsa; Du, Fangyong; Piatkov, Konstantin; Ghislain, Michel; Varshavsky, Alexander
Substrates of a ubiquitin-dependent proteolytic system called the N-end rule pathway include proteins with destabilizing N-terminal residues.

17. Planktonic and sediment-associated aerobic methanotrophs in two seep systems along the North American margin - Tavormina, Patricia L.; Ussler, William, III; Orphan, Victoria J.
Methane vents are of significant geochemical and ecological importance.

18. The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice is a Major Cause of CNS Pathology Resulting in Fatal Encephalitis - Lundberg, Patric; Ramakrishna, Chandran; Brown, Jeffrey; Tyszka, J. Michael; Hamamura, Mark; Hinton, David R.; Kovats, Susan; Nalcioglu, Orhan; Weinberg, Kenneth; Openshaw, Harry; Cantin, Edouard M.
Susceptible 129S6 (129) but not resistant C57BL/6 (B6) mice developed intense focal inflammatory brainstem lesions of primarily F4/80+ macrophages and Gr-1+ neutrophils detectable by MRI as early as day 6 post infection (PI).