Recursos de colección

Repositorio Institucional de la Universidad de Cordoba :: Spain (52.006 recursos)

El repositorio recoge todo tipo de materiales digitales: artículos de revistas, comunicaciones a congresos, tesis doctorales, documentos de trabajo, materiales docentes y objetos de aprendizaje, así como los productos digitales del patrimonio bibliográfico de la Universidad de Córdoba.

DMed-Artículos, capítulos...

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  1. Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health

    Morine, Melissa J.; Tierney, Audrey C.; Van Ommen, Ben; Daniel, Hannelore; Toomey, Sinead; Gjelstad, Ingrid M.F.; Gormley, Isobel C.; Drevon, Christian A.; Pérez-Martínez, Pablo; Roche, Helen M.; López-Miranda, José
    Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to pathway analysis, we have developed a joint multivariate and network-based approach to analysis of a dataset of habitual dietary records, adipose tissue transcriptomics and comprehensive plasma marker profiles from human volunteers with the Metabolic Syndrome. With this approach we identified prominent co-expressed sub-networks in the global metabolic network, which showed correlated expression with habitual n-3 PUFA intake and urinary levels of the oxidative stress marker 8-iso-PGF2a. These sub-networks illustrated inherent cross-talk between distinct metabolic pathways, such as between triglyceride metabolism and production of lipid signalling molecules....
    (application/pdf) - 14-dic-2017

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