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Enlighten (148.674 recursos)

Enlighten is the University of Glasgow's institutional repository service for published research material including peer-reviewed journal articles, published conference papers,books and book chapters

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Mostrando recursos 1 - 20 de 819

  1. Ot redaktorov zhurnala "Avtobiografiia": Russkie avtobiograficheskie teksty: vzgliad s Zapada (neskolko primerov iz opyta raboty zhurnala "Avtobiografiia")

    Gullotta, Andrea; Criveller, Claudia
    No abstract available.

  2. Early Developmental Activities and Computing Proficiency

    Cutts, Quintin; Patitsas, Elizabeth; Cole, Elizabeth; Donaldson, Peter; Alshaigy, Bedour; Gutica, Mirela; Hellas, Arto; Larraza-Mendiluze, Edurne; McCartney, Robert; Riedesel, Charles
    As countries adopt computing education for all pupils from primary school upwards, there are challenging indicators: significant proportions of students who choose to study computing at universities fail the introductory courses, and the evidence for links between formal education outcomes and success in CS is limited. Yet, as we know, some students succeed without prior computing experience. Why is this? Some argue for an innate ability, some for motivation, some for the discrepancies between the expectations of instructors and students, and some – simply – for how programming is being taught. All agree that becoming proficient in computing is not easy....

  3. Exome-wide association study of pancreatic cancer risk

    Grant, Robert C.; Denroche, Robert E.; Borgida, Ayelet; Virtanen, Carl; Cook, Natalie; Smith, Alyssa L.; Connor, Ashton A.; Wilson, Julie M.; Peterson, Gloria; Roberts, Nicholas J.; Klein, Alison P.; Grimmond, Sean M.; Biankin, Andrew; Cleary, Sean; Moore, Malcolm; Lemire, Mathieu; Zogopolous, George; Stein, Lincoln; Gallinger, Steven
    We conducted a case-control exome-wide association study to discover germline variants in coding regions that affect risk for pancreatic cancer, combining data from 5 studies. We analyzed exome and genome sequencing data from 437 patients with pancreatic cancer (cases) and 1922 individuals not known to have cancer (controls). In the primary analysis, BRCA2 had the strongest enrichment for rare inactivating variants (17/437 cases vs 3/1922 controls) (P=3.27x10(-6); exome-wide statistical significance threshold P<2.5x10(-6)). Cases had more rare inactivating variants in DNA repair genes than controls, even after excluding 13 genes known to predispose to pancreatic cancer (adjusted odds ratio, 1.35, P=.045)....

  4. Paraphernalia! Victorian Objects


  5. Photodynamic therapy leads to significant improvement of actinic keratosis area and severity index (AKASI)

    Schmitz, L.; von Dobbeler, C.; Gupta, G.; Gambichler, T.; Szeimies, R.M.; Morton, C.A.; Dirschka, T.
    Background: Actinic keratosis area and severity index (AKASI) is a new quantitative tool for assessing AK severity on the head and can be used to monitor outcomes of different therapies. The aim of this study was to determine treatment outcomes of AK applying AKASI three months after conventional photodynamic therapy (PDT). Methods: We performed a retrospective analysis of patients who have undergone PDT on the head and had a documented AKASI evaluation prior to PDT and at follow-up visits. Results: Of the 33 patients included, 32 (97.0%) patients showed an AKASI reduction and 1 (3.0%) patient an increase of AKASI at follow-up...

  6. The day of Orlando

    Randall, Bryony
    No abstract available.

  7. In amorous dedication: the phrase, the figure and the lover’s discourse

    Bromley, Amy
    No abstract available.

  8. Introduction

    Högberg, Elsa; Bromley, Amy
    No abstract available.

  9. Activating the 'Fund of Attention' to empower student peer review

    Camfield, Eileen Kogl; Killick, Lara; Lewis, Ruth

  10. Activating the 'Fund of Attention' to empower student peer review

    Camfield, Eileen Kogl; Killick, Lara; Lewis, Ruth

  11. Dating and relationship violence among 16-19 year olds in England and Wales: a cross-sectional study of types of victimisations by gender and risk factors

    Young, H.; Turney, C.; White, J.; Bonell, C.; Lewis, R.; Fletcher, A.

  12. Dating and relationship violence among 16-19 year olds in England and Wales: a cross-sectional study of types of victimisations by gender and risk factors

    Young, Honor; Turney, Catherine; White, James; Bonell, Chris; Lewis, Ruth; Fletcher, Adam
    Background: Dating and relationship violence (DRV) is under-researched in the UK, especially among Further Education (FE) students. This study examines the association between DRV victimization and socio-demographic characteristics, sexual identity and dating and relationship behaviours among 16–19 year olds FE students. Methods: Cross-sectional self-report data were collected from 1751 students aged 16–19 at six FE settings in England and Wales. Factor analysis examined the structure of DRV victimization by gender. Multilevel logistic regression examined the odds ratios of DRV victimization according to socio-demographics, sexual identity and dating behaviours. Results: DRV victimization clusters into two categories for females, and three for males. Among females, 46.1% experienced...

  13. Psychoeducational interventions in adolescent depression: A systematic review

    Bevan Jones, Rhys; Thapar, Anita; Stone, Zoe; Thapar, Ajay; Jones, Ian; Smith, Daniel; Simpson, Sharon
    Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions. There has been growing interest in psychoeducational interventions (PIs), which broadly deliver accurate information about health issues and self-management. Objective, methods: Systematic search of targeted PIs as part of prevention/management approaches for adolescent depression. Searches were undertaken independently in PubMed, PsycINFO, EMBASE, guidelines, reviews (including Cochrane), and reference lists. Key authors were contacted. No restrictions regarding publishing dates. Results: Fifteen studies were included: seven targeted adolescents with depression/depressive symptoms, eight targeted adolescents ‘at risk' e.g. with a family history of...

  14. Psychoeducational interventions in adolescent depression: A systematic review

    Bevan Jones, Rhys; Thapar, Anita; Stone, Zoe; Thapar, Ajay; Jones, Ian; Smith, Daniel; Simpson, Sharon
    Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions. There has been growing interest in psychoeducational interventions (PIs), which broadly deliver accurate information about health issues and self-management. Objective, methods: Systematic search of targeted PIs as part of prevention/management approaches for adolescent depression. Searches were undertaken independently in PubMed, PsycINFO, EMBASE, guidelines, reviews (including Cochrane), and reference lists. Key authors were contacted. No restrictions regarding publishing dates. Results: Fifteen studies were included: seven targeted adolescents with depression/depressive symptoms, eight targeted adolescents ‘at risk' e.g. with a family history of...

  15. Psychoeducational interventions in adolescent depression: A systematic review

    Bevan Jones, Rhys; Thapar, Anita; Stone, Zoe; Thapar, Ajay; Jones, Ian; Smith, Daniel; Simpson, Sharon
    Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions. There has been growing interest in psychoeducational interventions (PIs), which broadly deliver accurate information about health issues and self-management. Objective, methods: Systematic search of targeted PIs as part of prevention/management approaches for adolescent depression. Searches were undertaken independently in PubMed, PsycINFO, EMBASE, guidelines, reviews (including Cochrane), and reference lists. Key authors were contacted. No restrictions regarding publishing dates. Results: Fifteen studies were included: seven targeted adolescents with depression/depressive symptoms, eight targeted adolescents ‘at risk' e.g. with a family history of...

  16. The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila

    Vaughan, Leigh; Marley, Richard; Miellet, Sara; Hartley, Paul S.
    Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure. The mechanisms driving age-related tissue fibrosis and cardiac dysfunction are unclear, yet clinically important. Drosophila is amenable to the study of cardiac ageing as well as collagen deposition; however it is unclear whether collagen accumulates in the ageing Drosophila heart. This work examined collagen deposition and cardiac function in ageing Drosophila, in the context of reduced expression of collagen-interacting protein SPARC (Secreted Protein Acidic and Rich in Cysteine) an evolutionarily conserved protein linked...

  17. Investigating attitudes towards learning CS

    Cutts, Quintin; Donaldson, Peter
    This chapter explores the attitudes of computer science learners towards learning, as well as those of their teachers and how teaching practices may affect these attitudes. The exploration is set in the context of Carol Dweck’s Mindset, a concept with which many readers will be familiar or will have at least read about (Dweck, 2008). Mindset concerns how learners’ beliefs about their ability to learn directly affect their learning outcomes, and Mindset-based interventions have been successfully applied in computing contexts, for example in our own study (Cutts et al., 2010). However, Mindset has subtle consequences for teachers, which are often lost....

  18. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

    Maas, Andrew I R; Menon, David K; Adelson, P David; Andelic, Nada; Bell, Michael J; Belli, Antonio; Bragge, Peter; Brazinova, Alexandra; Büki, András; Chesnut, Randall M; Citerio, Giuseppe; Coburn, Mark; Cooper, D Jamie; Crowder, A Tamara; Czeiter, Endre; Czosnyka, Marek; Diaz-Arrastia, Ramon; Dreier, Jens P; Duhaime, Ann-Christine; Ercole, Ari; van Essen, Thomas A; Feigin, Valery L; Gao, Guoyi; Giacino, Joseph; Gonzalez-Lara, Laura E; Gruen, Russell L; Gupta, Deepak; Hartings, Jed A; Hill, Sean; Jiang, Ji-yao; Ketharanathan, Naomi; Kompanje, Erwin J O; Lanyon, Linda; Laureys, Steven; Lecky, Fiona; Levin, Harvey; Lingsma, Hester F; Maegele, Marc; Majdan, Marek; Manley, Geoffrey; Marsteller, Jill; Mascia, Luciana; McFadyen, Charles; Mondello, Stefania; Newcombe, Virginia; Palotie, Aarno; Parizel, Paul M; Peul, Wilco; Piercy, James; Polinder, Suzanne; Puybasset, Louis; Rasmussen, Todd E; Rossaint, Rolf; Smielewski, Peter; Söderberg, Jeannette; Stanworth, Simon J; Stein, Murray B; von Steinbüchel, Nicole; Stewart, William; Steyerberg, Ewout W; Stocchetti, Nino; Synnot, Anneliese; Te Ao, Braden; Tenovuo, Olli; Theadom, Alice; Tibboel, Dick; Videtta, Walter; Wang, Kevin K W; Williams, W Huw; Wilson, Lindsay; Yaffe, Kristine; Adams, Hadie; Agnoletti, Vanni; Allanson, Judith; Amrein, Krisztina; Andaluz, Norberto; Anke, Audny; Antoni, Anna; van As, Arjan Bastiaan; Audibert, Gérard; Azaševac, Antun; Azouvi, Philippe; Azzolini, Maria Luisa; Baciu, Camelia; Badenes, Rafael; Barlow, Karen M; Bartels, Ronald; Bauerfeind, Ursula; Beauchamp, Miriam; Beer, Darcy; Beer, Ronny; Belda, Francisco Javier; Bellander, Bo-Michael; Bellier, Rémy; Benali, Habib; Benard, Thierry; Beqiri, Valzerda; Beretta, Luigi; Bernard, Francis; Bertolini, Guido; Bilotta, Federico; Blaabjerg, Morten; den Boogert, Hugo; Boutis, Kathy; Bouzat, Pierre; Brooks, Brian; Brorsson, Camilla; Bullinger, Monika; Burns, Emma; Calappi, Emiliana; Cameron, Peter; Carise, Elsa; Castaño-León, Ana M; Causin, Francesco; Chevallard, Giorgio; Chieregato, Arturo; Christie, Brian; Cnossen, Maryse; Coles, Jonathan; Collett, Johnny; Della Corte, Francesco; Craig, William; Csato, Gabor; Csomos, Akos; Curry, Nicola; Dahyot-Fizelier, Claire; Dawes, Helen; DeMatteo, Carol; Depreitere, Bart; Dewey, Deborah; van Dijck, Jeroen; Đilvesi, Đula; Dippel, Diederik; Dizdarevic, Kemal; Donoghue, Emma; Duek, Or; Dulière, Guy-Loup; Dzeko, Adelaida; Eapen, George; Emery, Carolyn A; English, Shane; Esser, Patrick; Ezer, Erzsébet; Fabricius, Martin; Feng, Junfeng; Fergusson, Dean; Figaji, Anthony; Fleming, Joanne; Foks, Kelly; Francony, Gilles; Freedman, Stephen; Freo, Ulderico; Frisvold, Shirin K; Gagnon, Isabelle; Galanaud, Damien; Gantner, Dashiell; Giraud, Benoit; Glocker, Ben; Golubovic, Jagoš; Gómez López, Pedro A; Gordon, Wayne A; Gradisek, Primoz; Gravel, Jocelyn; Griesdale, Donald; Grossi, Francesca; Haagsma, Juanita A; Håberg, Asta Kristine; Haitsma, Iain; Van Hecke, Wim; Helbok, Raimund; Helseth, Eirik; van Heugten, Caroline; Hoedemaekers, Cornelia; Höfer, Stefan; Horton, Lindsay; Hui, Jiyuan; Huijben, Jilske Antonia; Hutchinson, Peter J; Jacobs, Bram; van der Jagt, Mathieu; Jankowski, Stefan; Janssens, Koen; Jelaca, Bojan; Jones, Kelly M; Kamnitsas, Konstantinos; Kaps, Rafael; Karan, Mladen; Katila, Ari; Kaukonen, Kirsi-Maija; De Keyser, Véronique; Kivisaari, Riku; Kolias, Angelos G; Kolumbán, Bálint; Kolundžija, Ksenija; Kondziella, Daniel; Koskinen, Lars-Owe; Kovács, Noémi; Kramer, Andreas; Kutsogiannis, Demitri; Kyprianou, Theodoros; Lagares, Alfonso; Lamontagne, François; Latini, Roberto; Lauzier, François; Lazar, Isaac; Ledig, Christian; Lefering, Rolf; Legrand, Valerie; Levi, Leon; Lightfoot, Roger; Lozano, Angels; MacDonald, Stephen; Major, Sebastian; Manara, Alex; Manhes, Pauline; Maréchal, Hugues; Martino, Costanza; Masala, Alessandro; Masson, Serge; Mattern, Julia; McFadyen, Bradford; McMahon, Catherine; Meade, Maureen; Melegh, Béla; Menovsky, Tomas; Moore, Lynne; Morgado Correia, Marta; Morganti-Kossmann, Maria Cristina; Muehlan, Holger; Mukherjee, Pratik; Murray, Lynnette; van der Naalt, Joukje; Negru, Ancuta; Nelson, David; Nieboer, Daan; Noirhomme, Quentin; Nyirádi, József; Oddo, Mauro; Okonkwo, David O; Oldenbeuving, Annemarie W; Ortolano, Fabrizio; Osmond, Martin; Payen, Jean-François; Perlbarg, Vincent; Persona, Paolo; Pichon, Nicolas; Piippo-Karjalainen, Anna; Pili-Floury, Sébastien; Pirinen, Matti; Ple, Horia; Poca, Maria Antonia; Posti, Jussi; Van Praag, Dominique; Ptito, Alain; Radoi, Andreea; Ragauskas, Arminas; Raj, Rahul; Real, Ruben G L; Reed, Nick; Rhodes, Jonathan; Robertson, Claudia; Rocka, Saulius; Røe, Cecilie; Røise, Olav; Roks, Gerwin; Rosand, Jonathan; Rosenfeld, Jeffrey V; Rosenlund, Christina; Rosenthal, Guy; Rossi, Sandra; Rueckert, Daniel; de Ruiter, Godard C W; Sacchi, Marco; Sahakian, Barbara J; Sahuquillo, Juan; Sakowitz, Oliver; Salvato, Gerardo; Sánchez-Porras, Renán; Sándor, János; Sangha, Grinder; Schäfer, Nadine; Schmidt, Silke; Schneider, Kathryn J; Schnyer, David; Schöhl, Herbert; Schoonman, Guus G; Schou, Rico Frederik; Sir, Özcan; Skandsen, Toril; Smeets, Dirk; Sorinola, Abayomi; Stamatakis, Emmanuel; Stevanovic, Ana; Stevens, Robert D; Sundström, Nina; Taccone, Fabio Silvio; Takala, Riikka; Tanskanen, Päivi; Taylor, Mark Steven; Telgmann, Ralph; Temkin, Nancy; Teodorani, Guido; Thomas, Matt; Tolias, Christos M; Trapani, Tony; Turgeon, Alexis; Vajkoczy, Peter; Valadka, Alex B; Valeinis, Egils; Vallance, Shirley; Vámos, Zoltán; Vargiolu, Alessia; Vega, Emmanuel; Verheyden, Jan; Vik, Anne; Vilcinis, Rimantas; Vleggeert-Lankamp, Carmen; Vogt, Lidia; Volovici, Victor; Voormolen, Daphne C; Vulekovic, Peter; Vande Vyvere, Thijs; Van Waesberghe, Julia; Wessels, Lars; Wildschut, Eno; Williams, Guy; Winkler, Maren K L; Wolf, Stefan; Wood, Gordon; Xirouchaki, Nektaria; Younsi, Alexander; Zaaroor, Menashe; Zelinkova, Veronika; Zemek, Roger; Zumbo, Fabrizio
    No abstract available.

  19. A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

    Desombere, Isabelle; Mesalam, Ahmed Atef; Urbanowicz, Richard A.; Van Houtte, Freya; Verhoye, Lieven; Keck, Zhen-Yong; Farhoudi, Ali; Vercauteren, Koen; Weening, Karin E.; Baumert, Thomas F.; Patel, Arvind H.; Foung, Steven K.H.; Ball, Jonathan; Leroux-Roels, Geert; Meuleman, Philip
    Infections with hepatitis C virus (HCV) represent a worldwide health burden and a prophylactic vaccine is still not available. Liver transplantation (LT) is often the only option for patients with HCV-induced end-stage liver disease. However, immediately after transplantation, the liver graft becomes infected by circulating virus, resulting in accelerated progression of liver disease. Although the efficacy of HCV treatment using direct-acting antivirals has improved significantly, immune compromised LT-patients and patients with advanced liver disease remain difficult to treat. As an alternative approach, interfering with viral entry could prevent infection of the donor liver. We generated a human monoclonal antibody (mAb),...

  20. A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

    Desombere, Isabelle; Mesalam, Ahmed Atef; Urbanowicz, Richard A.; Van Houtte, Freya; Verhoye, Lieven; Keck, Zhen-Yong; Farhoudi, Ali; Vercauteren, Koen; Weening, Karin E.; Baumert, Thomas F.; Patel, Arvind H.; Foung, Steven K.H.; Ball, Jonathan; Leroux-Roels, Geert; Meuleman, Philip
    Infections with hepatitis C virus (HCV) represent a worldwide health burden and a prophylactic vaccine is still not available. Liver transplantation (LT) is often the only option for patients with HCV-induced end-stage liver disease. However, immediately after transplantation, the liver graft becomes infected by circulating virus, resulting in accelerated progression of liver disease. Although the efficacy of HCV treatment using direct-acting antivirals has improved significantly, immune compromised LT-patients and patients with advanced liver disease remain difficult to treat. As an alternative approach, interfering with viral entry could prevent infection of the donor liver. We generated a human monoclonal antibody (mAb),...

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