Recursos de colección

IOE EPrints (18.097 recursos)

IOE EPrints is a repository that collects together the work of researchers and allows them to make their research outputs freely available over the web via a searchable "open access" database.

Mostrando recursos 41 - 60 de 81

  1. Tree-oriented vs. line-oriented Observation-Based Slicing

    Binkley, D; Gold, NE; Islam, S; Krinke, J; Yoo, S

  2. From fish to frogs and beyond: Impact and host range of emergent ranaviruses

    Price, SJ; Ariel, E; Maclaine, A; Rosa, GM; Gray, MJ; Brunner, JL; Garner, TWJ
    Ranaviruses are pathogens of ectothermic vertebrates, including amphibians. We reviewed patterns of host range and virulence of ranaviruses in the context of virus genotype and postulate that patterns reflect significant variation in the historical and current host range of three groups of Ranavirus: FV3-like, CMTV-like and ATV-like ranaviruses. Our synthesis supports previous hypotheses about host range and jumps: FV3s are amphibian specialists, while ATVs are predominantly fish specialists that switched once to caudate amphibians. The most recent common ancestor of CMTV-like ranaviruses and FV3-like forms appears to have infected amphibians but CMTV-like ranaviruses may circulate in both amphibian and fish...

  3. The impact of static and dynamic roughness elements on flow separation

    Servini, P; Smith, FT; Rothmayer, AP
    The use of static or dynamic roughness elements has been shown in the past to delay the separation of a laminar boundary layer from a solid surface. Here, we examine analytically the effect of such elements on the local and breakaway separation points, corresponding respectively to the position of zero skin friction and presence of a singularity in the roughness region, for flow over a hump embedded within the boundary layer. Two types of roughness elements are studied: the first is small and placed near the point of vanishing skin friction; the second is larger and extends downstream. The forced...

  4. Examining ethnic variations in sexual behaviours and sexual health markers: evidence from a British national probability sample survey

    Wayal, S; Hughes, G; sonnenberg, P; Mohammed, H; copas, AJ; Gerressu, M; Tanton, C; Furegato, M; Mercer, C

  5. Shaping the structure of legal opportunities: Environmental NGOs bringing international environmental procedural rights back home

    Vanhala, L

  6. Process tracing in the study of environmental politics

    Vanhala, L

  7. Children critique learning the ‘pure’ subject of English in the traditional classroom

    Hargreaves, E; Elhawary, D; Mahgoub, M
    This paper makes a sociological exploration of the enforcement of strong boundaries between “pure” (disciplinary) and “applied” (common-sense) knowledge in primary school English classrooms. This article is innovative in its focus on how pupils describe and evaluate their own experiences. It addressed the research question: How do primary pupils experience the traditional classroom and what suggestions do they and their teachers express for making improvements to English language learning? We used observations in 18 classrooms, a written sentence-starter activity with 394 pupils and extended individual interviews with 38 pupils in Egyptian Government primary schools. The research took place in the...

  8. Commentary: A refresh for evidence based psychological therapies – reflections on Marchette and Weisz (2017)

    Fonagy, P; ALlison, E
    Is the introduction of evidence-based psychotherapy into mainstream child and adolescent mental health services (CAMHS) a breakthrough for a scientific approach to child mental health? Or are we still in the dark ages despite our best efforts to link evidence with practice (EBP)? Marchette and Weisz (2017) review three treatment strategies that have the potential to establish a pattern of clinical practice that would allow the discoveries of a rigorous developmental science to inform the average practitioner’s work with their routine caseloads. Their review suggests that this can be achieved in a manner that does justice to the concerns of...

  9. Tuneable Plasmonic Gold Dendrimer Nanochains for Sensitive Disease Detection

    Ruiz Sanchez, AJ; Parolo, C; Miller, BS; Gray, ER; Schlegel, K; McKendry, RA
    We report the development of a tuneable plasmonic nanochain immunoassay with increased sensitivity over traditional monodisperse nanoparticle lateral flow tests. Our approach takes advantage of the unique self-assembling properties of polyamidoamine dendrimers with gold nanoparticles in aqueous media to create one-dimensional nanochains, with a distinct red to blue colour change, attributable to a longitudinal plasmon resonance, which can be readily detected by eye and a digital camera. We optimise and characterise nanochain formation and stability using UV-visible spectroscopy, transmission electron microscopy and dynamic light scattering. As a proof-of-principle we focus on the application of nanochains for point-of-care diagnostics for p24,...

  10. Did the accuracy of oral amoxicillin dosing of children improve after British National Formulary dose revisions in 2014?: national cross sectional survey in England

    Rann, O; Sharland, M; Long, P; Wong, ICK; Laverty, AA; Bottle, A; Barker, CI; Bielicki, J; Saxena, S
    OBJECTIVES: Inaccurate antibiotic dosing can lead to treatment failure, fuel antimicrobial resistance and increase side effects. The British National Formulary for Children (BNFC) guidance recommends oral antibiotic dosing according to age bands as a proxy for weight. Recommended doses of amoxicillin for children were increased in 2014 ‘after widespread concerns of under dosing’. However, the impact of dose changes on British children of different weights is unknown, particularly given the rising prevalence of childhood obesity in the UK. We aimed to estimate the accuracy of oral amoxicillin dosing in British children before and after the revised BNFC guidance in 2014. SETTING...

  11. Nonlinearity Compensation and Information Rates in Fully- Loaded C-band Optical Fibre Transmission Systems

    Xu, T; Shevchenko,; Karanov,; Lavery,; Galdino,; Alvarado, A; Killey,; Bayvel,

  12. Review article: dyssynergic defaecation and biofeedback therapy in the pathophysiology and management of functional constipation

    Skardoon, GR; Khera, AJ; Emmanuel, AV; Burgell, RE
    BACKGROUND: Functional constipation is a common clinical presentation in primary care. Functional defaecation disorders are defined as the paradoxical contraction or inadequate relaxation of the pelvic floor muscles during attempted defaecation (dyssynergic defaecation) and/or inadequate propulsive forces during attempted defaecation. Prompt diagnosis and management of dyssynergic defaecation is hindered by uncertainty regarding nomenclature, diagnostic criteria, pathophysiology and efficacy of management options such as biofeedback therapy. AIM: To review the evidence pertaining to the pathophysiology of functional defaecation disorders and the efficacy of biofeedback therapy in the management of patients with dyssynergic defaecation and functional constipation. METHODS: Relevant articles addressing functional defaecation disorders...

  13. Neurogenic bowel dysfunction: Clinical management recommendations of the Neurologic Incontinence Committee of the Fifth International Consultation on Incontinence 2013.

    Cotterill, N; Madersbacher, H; Wyndaele, JJ; Apostolidis, A; Drake, MJ; Gajewski, J; Heesakkers, J; Panicker, J; Radziszewski, P; Sakakibara, R; Sievert, K-D; Hamid, R; Kessler, TM; Emmanuel, A
    BACKGROUND: Evidence-based guidelines for the management of neurological disease and lower bowel dysfunction have been produced by the International Consultations on Incontinence (ICI). These are comprehensive guidelines, and were developed to have world-wide relevance. AIMS: To update clinical management of neurogenic bowel dysfunction from the recommendations of the 4th ICI, 2009. MATERIALS AND METHODS: A series of evidence reviews and updates were performed by members of the working group. The resulting guidelines were presented at the 2012 meeting of the European Association of Urology for consultation, and modifications applied to deliver evidence based conclusions and recommendations for the scientific report...

  14. On rate limitation mechanisms for TCP throughput: A longitudinal analysis

    Araujo, JT; Landa, R; Clegg, RG; Pavlou, G; Fukuda, K
    TCP remains the dominant transport protocol for Internet traffic. It is usually considered to have its sending rate covered by a sliding window congestion control mechanism. However, in addition to this normal congestion control, a number of other mechanisms limit TCP throughput. This paper analyses the extent to which network, host and application settings define flow throughput over time and across autonomous systems. Our study draws on data from a longitudinal study spanning five years of passive traces collected from a single transit link. Mechanisms for this include limiting by application, interference with the TCP window control mechanism and artificial...

  15. An International Urogynecological Association (IUGA)/International Continence Society (ICS) Joint Report on the Terminology for Female Anorectal Dysfunction

    Sultan, AH; Monga, A; Lee, J; Emmanuel, A; Norton, C; Santoro, G; Hull, T; Berghmans, B; Brody, S; Haylen, BT
    INTRODUCTION: The terminology for anorectal dysfunction in women has long been in need of a specific clinically-based Consensus Report. METHODS: This Report combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS), assisted on Committee by experts in their fields to form a Joint IUGA/ICS Working Group on Female Anorectal Terminology. Appropriate core clinical categories and sub classifications were developed to give an alphanumeric coding to each definition. An extensive process of twenty rounds of internal and external review was developed to exhaustively examine each...

  16. Interacting with Multi-media, Multi-user Systems: Observations on Multi-Media Conferencing Tools

    Sasse, MA; Fentem, AC
    Interactive multi-media, multi-user systems systems are becoming increasingly common. Such systems have the potential to change the way in which we work and communicate, since they create the basis for applications in teleworking, distance education and global collaborative projects. Guidelines and design principles aimed at producing effective user interfaces to such systems have been put forward in the CSCW and multimedia literature. This paper introduces some of these guidelines, and examines whether they address the usability problems observed with such systems. The observations were obtained through a small exploratory study with a multimedia conferencing system. We identified several of the...

  17. Editorial

    Tiedau, U

  18. International spinal cord injury bowel function basic data set (Version 2.0)

    Krogh, K; Emmanuel, A; Perrouin-Verbe, B; Korsten, MA; Mulcahey, MJ; Biering-Sorensen, F
    Study design: International expert working group. Objectives: To revise the International Spinal Cord Injury (SCI) Bowel Function Basic Data Set as a standardized format for the collecting and reporting of a minimal amount of information on bowel function in clinical practice and research. Setting: Working group appointed by the American Spinal injury association (ASIA) and the International Spinal Cord Society (ISCoS). Methods: The draft prepared by the working group was reviewed by the International SCI Data Set Committee and later by members of the ISCoS Executive and Scientific Committees and the ASIA board. The revised data set was posted on the ASIA and ISCoS websites for 1...

  19. Five-year follow-up of underexpanded and overexpanded bioresorbable scaffolds: self-correction and impact on shear stress

    Torii, R; Tenekecioglu, E; Bourantas, C; Poon, E; Thondapu, V; Gijsen, F; Sotomi, Y; Onuma, Y; Barlis, P; Ooi, ASH; Serruys, PW
    Underexpansion and overexpansion have been incriminated as causative factors of adverse cardiac events. However, dynamic biological interaction between vessel wall and scaffold may attenuate the adverse haemodynamic impact of overexpansion or underexpansion.

  20. Human brain networks: consensus, reproducibility, inter-modal comparison and epilepsy pathology

    Parker, CS
    Classical and contemporary research in neuroscience postulates that connectivity is a fundamental component of human brain function. Recently, advances in computational neuroimaging have enabled reconstruction of macroscopic human brain structural connectivity in vivo using diffusion MRI. Studies show that the structural network topology may discriminate between neurological phenotypes or relate to individual brain function. To investigate disease effectively, it is necessary to determine the network methodological and biological variability. Reproducibility was calculated for two state-of-the-art reconstruction pipelines in healthy subjects. High reproducibility of connection weights was observed, which increased with connection strength. A high agreement between pipelines was found across...

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