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É um repositório para instituições de ensino e investigação produtoras de literatura científica cuja dimensão ainda não justifica a criação de um repositório próprio. Permite integrar instituições, grupos ou indivíduos na infra-estrutura do projecto, nomeadamente através das pesquisas do Portal RCAAP e da B-On.

S - Cuf - Porto - Artigos Científicos

Mostrando recursos 1 - 20 de 20

  1. Correcção endovascular de aneurisma da artéria esplénica: caso clínico

    Lopes, JA; Brandão, D; Mansilha, A
    Splenic artery aneurysms, although they are the most common splanchnic aneurysms, they have a prevalence of only 0,01%. In this context the authors present a case report of a 41 years female patient with a splenic artery aneurysm of 20x29mm, treated by deployment of a covered self-expandable stent (Gore® Viabahn®). It is performed a literature review of the pathology in question, possible complications and made reference to the various treatment options, with particular emphasis on the new endovascular techniques.

  2. Estratégia terapêutica na doença venosa crónica

    Medeiros, J; Mansilha, A
    Chronic venous disease (CVD) is a highly prevalent pathology that compromises patient’s quality of life, and has an important impact socioeconomically. Its treatment passes through the adoption of hygiene-dietetic measures, pharmacological therapy and elastic compression, as well as approaches that are able to ablate venous reflux and hypertension such as mechanical, thermic or chemical ablations. Due to the multiplicity of therapeutic approaches available nowadays, it is important to search for the more effective ones. The objective of this work is to establish a systematic clinical orientation for patients with chronic venous disease, taking into account the CEAP classification, the published results and...

  3. Aneurisma venoso palmar: caso clínico

    Lopes, JA; Brandão, D; Figueiredo, A; Mansilha, A

  4. Body Fat Percentage Is a Major Determinant of Total Bilirubin Independently of UGT1A1*28 Polymorphism in Young Obese

    Belo, L; Nascimento, H; Kohlova, M; Bronze-da-Rocha, E; Fernandes, J; Costa, E; Catarino, C; Aires, L; Mansilha, HF; Rocha-Pereira, P; Quintanilha, A; Rêgo, C; Santos-Silva, A
    OBJECTIVES: Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of bilirubin levels and recent evidence suggests that raised adiposity may also be a contributing factor. We aimed to study the interaction between UGT1A1 polymorphism, hematological and anthropometric variables with total bilirubin levels in young individuals. METHODS: 350 obese (mean age of 11.6 years; 52% females) and 79 controls (mean age of 10.5 years; 59% females) were included. Total bilirubin and C-reactive protein (CRP) plasma levels, hemogram, anthropometric data and UGT1A1 polymorphism were determined. In a subgroup of 74 obese and 40...

  5. Effects of atopy and rhinitis on exhaled nitric oxide values - a systematic review

    Linhares, D; Jacinto, T; Pereira, AM; Fonseca, JA
    BACKGROUND: Atopy and rhinitis are among the factors affecting exhaled nitric oxide (FeNO) values and may contribute to difficulties in the clinical interpretation of FeNO measurements. However, data assessing their effects on FeNO values had never been summarized. This review aims to evaluate the effect of atopy and rhinitis in FeNO values in otherwise healthy individuals. METHODS: A systematic review was performed in Pubmed, Scopus and ISI Web of Knowledge. A two-step selection process was completed, and from 2357 references 19 were included. The inclusion criteria were: participants without known diseases other than rhinitis; atopy assessement by SPT or Specific IgE; and FeNO...

  6. Control of Allergic Rhinitis and Asthma Test (CARAT) can be used to assess individual patients over time

    Fonseca, JA; Nogueira-Silva, L; Morais-Almeida, M; Sá-Sousa, A; Azevedo, LF; Ferreira, J; Branco-Ferreira, M; Rodrigues-Alves, R; Bugalho-Almeida, A; Bousquet, J
    BACKGROUND: The Control of Allergic Rhinitis and Asthma Test (CARAT10) has been proposed as the first tool to implement the Allergic Rhinitis and its Impact on Asthma initiative guidelines in clinical practice. To serve this purpose, it must have adequate properties to assess the control of an individual over time. This study aimed to prospectively assess the test-retest reliability, responsiveness and longitudinal validity of CARAT10. METHODS: Adults with asthma and allergic rhinitis were enrolled at 4 outpatient clinics of Portuguese central hospitals. At each of the two visits, 4 to 6 weeks apart, patients filled out CARAT10 and additional questionnaires, followed by a...

  7. Setting reference values for exhaled nitric oxide: a systematic review

    Jacinto, T; Alving, K; Correia, R; Costa-Pereira, A; Fonseca, JA
    BACKGROUND: The values obtained when the fraction of exhaled nitric oxide (FeNO) is measured are affected by several factors that are specific to the individual patient, making interpretation difficult, especially in the initial assessment of patients with respiratory symptoms. METHODS: Systematic review of studies on FeNO reference values and individual-specific factors that influence them. RESULTS: From 3739 references, 15 studies were included. Four studies included children and adolescents. In nine studies, samples were selected from the general population. Most studies reported objective measures for atopy (nine studies), but not for smoking status (one). Significant determinants of FeNO values reported were age and height (seven studies),...

  8. Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects

    Malinovschi, A; Fonseca, JA; Jacinto, T; Alving, K; Janson, C
    BACKGROUND: Fraction of exhaled nitric oxide (Feno) and blood eosinophil count (B-Eos) values, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients. Little is known about the relation of these markers to reported wheeze and asthma events in a random population sample. OBJECTIVES: We sought to determine the individual and independent values of B-Eos and Feno in relation to wheeze, asthma diagnosis, and asthma events in a cross-sectional study. METHODS: Feno and B-Eos values were measured in 12,408 subjects aged 6 to 80 years from the National Health and Nutrition Examination Survey 2007-2008 and 2009-2010. Current wheeze and asthma diagnosis, as...

  9. Environmental tobacco smoke exposure at home and smoking prevalence in the general Portuguese population--the INAsma study

    Pereira, AM; Morais-Almeida, M; Sá e Sousa, A; Jacinto, T; Azevedo, LF; Robalo-Cordeiro, C; Bugalho de Almeida, A; Fonseca, JA
    BACKGROUND: We aimed to: 1) estimate the prevalence of exposure to environmental tobacco smoke (ETS) at home in the Portuguese population; 2) estimate tobacco smoking prevalence in Portugal; 3) identify social and personal characteristics associated with smoking or exposure to ETS. METHODS: Nationwide, cross-sectional, population-based telephone survey. Overall, 6003 individuals completed the interview. ETS exposure at home was defined as exposure to at least one current smoker at home. A smoker was defined as someone with 15 years or older, smoking at least 1 cigarette per day during a year; a current smoker (CS) smoked in the last month. RESULTS: Exposure to ETS at home...

  10. Control of Allergic Rhinitis and Asthma Test (CARAT): dissemination and applications in primary care

    Azevedo, P; Correia de Sousa, J; Bousquet, J; Bugalho-Almeida, A; Del Giacco, SR; Demoly, P; Haahtela, T; Jacinto, T; Garcia-Larsen, V; van der Molen, T; Morais-Almeida, M; Nogueira-Silva, L; Pereira, AM; Rodríguez, MR; Silva, BG; Tsiligianni, IG; Yaman, H; Yawn, B; Fonseca, JA; WHO Collaborative Center for Asthma and Rhinitis, Montpellier
    Asthma frequently occurs in association with allergic rhinitis and a combined management approach has been suggested. The Control of Allergic Rhinitis and Asthma Test (CARAT) is the first questionnaire to assess control of both diseases concurrently. However, to have an impact on healthcare it needs to be disseminated and adopted. In this paper we discuss the dissemination of CARAT in different countries and its possible applications in primary care. At present, the adaptation of CARAT for use in different languages and cultures is being led by volunteer researchers and clinicians in 15 countries. Website and smartphone applications have been developed,...

  11. Bacterial cellulose membranes as drug delivery systems: An in vivo skin compatibility study

    Almeida, IF; Pereira, T; Silva, NH; Gomes, FP; Silvestre, AJ; Freire, CS; Sousa-Lobo, JM; Costa, PC
    Bacterial cellulose (BC) is a highly pure form of cellulose, produced in the form of a swollen membrane by several bacteria that demonstrated to be able to modulate the skin release of model drugs. In the present study, the skin irritation potential of BC was evaluated in human subjects. BC membranes with and without glycerin (acting as plasticizer) were tested. No significant differences were observed for transepidermal water loss (TEWL) measurements in comparison with negative control, 2 and 24h after patch removal, which is an indicator of an absence of barrier disruption. Similar results were found for erythema. Clinical scores...

  12. Prevalence and classification of rhinitis in the elderly: a nationwide survey in Portugal

    Morais-Almeida, M; Pite, H; Pereira, AM; Todo-Bom, A; Nunes, C; Bousquet, J; Fonseca, JA
    BACKGROUND: Nationwide epidemiologic data on rhinitis in the elderly do not exist. This study aimed to estimate the prevalence of rhinitis in the population aged 65 years or above in mainland Portugal and to characterize and classify rhinitis in this age group. METHODS: Cross-sectional, nationwide, population-based survey of citizens aged 65 years or above, living in mainland Portugal. Current rhinitis (CR) was defined as the presence of at least two symptoms: 'repeated sneezing and itchy nose', 'blocked nose for more than one whole hour', or 'runny nose when not having a cold or flu', either usually or in the last 12 months. Rhinitis...

  13. Prevalence and classification of rhinitis in preschool children in Portugal: a nationwide study.

    Morais-Almeida, M; Santos, N; Pereira, AM; Branco-Ferreira, M; Nunes, C; Bousquet, J; Fonseca, JA
    BACKGROUND: Information on rhinitis epidemiology in preschool children is scarce. OBJECTIVES: To estimate, in children with 3-5 years of age, current rhinitis prevalence, to describe rhinitis symptoms and associated sociodemographic characteristics, and to report allergic rhinitis and its impact on asthma (ARIA) classification. METHODS: Cross-sectional, nationwide, population-based study including children aged 3-5 years. A multistep selection strategy was used to obtain a representative sample. Data were collected at kindergartens and parish centers by face-to-face interview to caregivers, using an adapted ISAAC questionnaire. 'Current rhinitis' (CR) was defined as the presence of ≥1 rhinitis symptom (repeated sneezing and/or itchy nose, blocked nose for >1 h, or...

  14. Cutaneous mastocytosis: Two pediatric cases treated with topical pimecrolimus.

    Correia, O; Duarte, AF; Quirino, P; Azevedo, R; Delgado, L
    Cutaneous mastocytosis is characterized by increased numbers of skin mast cells that release mediators causing pruritus, urticaria, and flushing. Most pediatric mastocytosis patients exhibit the pattern of urticaria pigmentosa, which typically appears during the first two years of life and resolves spontaneously in late adolescence. However, while the disease is active, patients are frequently symptomatic and uncomfortable, which justifies symptomatic treatment. We report 2 patients, a 14-month-old girl and a 26-month-old boy, with localized cutaneous erythematous lesions with a positive Darier sign. In each, a punch biopsy confirmed the diagnosis of mastocytosis. Treatment was instituted with pimecrolimus cream twice a...

  15. Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

    Pimenta, R; Carvalho, P; Amado, P
    OBJECTIVES: The treatment of severe post-traumatic ankle arthritis remains a challenge nowadays. Since patients suffering from this pathology are mainly young and active people, a correct reconstruction, if possible, of the articular cartilage defects of the tibiotalar joint is very important to achieve a good result. Fresh bipolar osteochondral allograft (FBOA) is a promising operative technique, as an alternative to arthrodesis and total ankle replacement, in pain relief, restoration of function and indefinite delay of arthritic disease progression. METHODS: The authors made a review of the literature and present a case report of a young 30 years-old man, with bilateral post-traumatic osteoarthritis of...

  16. Nail surgery.

    Haneke, E

  17. Internal iliac and uterine arteries Doppler ultrasound in the assessment of normotensive and chronic hypertensive pregnant women

    Guedes-Martins, L; Cunha, A; Saraiva, J; Gaio, R; Macedo, F; Almeida, H
    The objective of this work was to compare Doppler flows pulsatility index (PI) and resistance indexes (RI) of uterine and internal iliac arteries during pregnancy in low risk women and in those with stage-1 essential hypertension. From January 2010 and December 2012, a longitudinal and prospective study was carried out in 103 singleton uneventful pregnancies (72 low-risk pregnancies and 31 with stage 1 essential hypertension)at the 1(st), 2(nd) and 3(rd) trimesters. Multiple linear regression models, fitted using generalized least squares and whose errors were allowed to be correlated and/or have unequal variances, were employed; a model for the relative differences...

  18. Anomalous coronary origin: From suspicion to surgical revascularization

    Vieira, C; Nabais, C; Salgado, A; Salomé, N; Sousa, P; Madureira, AJ; Pinho, P
    Congenital anomalies of the coronary arteries are uncommon and can present a diagnostic challenge. The authors present the case of a patient with recurrent chest pain during exertion admitted for acute coronary syndrome. Coronary angiography revealed no coronary lesions but showed that the right coronary artery originated from the anterolateral aortic wall, above the sinuses of Valsalva, leading to suspicion of compression by the pulmonary artery, confirmed by CT angiography. The patient underwent surgical revascularization with a good result. The authors highlight the need to consider compression of an anomalous coronary artery by the pulmonary artery in the differential diagnosis...

  19. Advanced nail surgery

    Haneke, E
    Six techniques not yet widely known or used in the dermatologic surgery of the nails are briefly described. Small-to-medium-sized tumours of the proximal nail fold (PNF) can be excised and the defect repaired with advancement or rotation flaps. A superficial biopsy technique of the matrix for the diagnosis of longitudinal brown streaks in the nail, which allows rapid histological diagnosis of the melanocyte focus to be performed, is described here. Because the excision is very shallow and leaves the morphogenetic connective tissue of the matrix intact, the defect heals without scarring. Laterally positioned nail tumours can be excised in the...

  20. Comment on subungual vascular malformation with unusual presentation

    Haneke, E

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