Vale, P; Guerreiro, R; Luiz, P; Gonçalves, G; Areias, F; Nunes, A; Mocho, A; Garcia, P; Berdeja, A; Avelar, C
A retrospective study of the newborns who were submitted to mechanical ventilation at the Neonatal Intermediate Care Unit was made between July 1991 and June 1994. Mechanical ventilation in such a unit should be transitory and not exceed 24 hours. Information concerning pregnancy, labour, neonates, type of ventilation and its problems was gathered. Forty seven neonates were ventilated. The average ventilation time was six hours (1-20 hours). The main cause of ventilation was hyaline membrane disease which occurred in 24% of all cases. Mortality observed was 16.6% and some sequellae were registered which were related not only to ventilation but...
Lito, D; Pignatelli, D; Simões, AS; Carvalho, A; Cunha, F
Brissos, J; Carrusca, C; Correia, M; Cabral, J
A rational and appropriate evaluation of liver biochemical tests is essential, given the increased number of abnormal laboratory results in asymptomatic patients. Critical judgement allows early diagnosis in the absence of typical clinical signs. Autoimmune hepatitis is a rare disease with high clinical variability. We present a child investigated for unexplained increase in aminotransferases, discovered accidentally 2 months earlier in a standard laboratory panel approach. She was asymptomatic and no physical signs of chronic or acute liver disease were found. Laboratory investigation showed hypergammaglobulinaemia with selective elevation of IgG and a positive anti-liver cytosol type 1. Severe interface hepatitis was...
Simões, AS; Peres, A; Valente, S; Casimiro, A; Cunha, F
Esteves, I; Crispim, J; Neves, JF; Cunha, F
Neves, JF; Rodrigues, P; Peres, A; Constantino, C; Cunha, F
Rodrigues, P; Peres, A; Simões, AS; Cunha, F
Peres, A; Pimentel, S; Tuna, M; Cunha, F
Lito, D; Francisco, T; Salva, I; Tavares, M; Rodrigues, R; Neto, MT
Systematic screening for TORCH infections and group B Streptococcus (GBS) during pregnancy has been an important factor in the improvement of perinatal care.
To evaluate TORCH serology and GBS carriers state in the population of a maternity, to assess variability with age and nationality and to search for congenital infections.
MATERIAL AND METHODS:
Non-probabilistic prevalence study.
9508 TORCH and 2639 GBS results were registered. Immunity rate for rubella was 93.3%, higher for Portuguese women; for toxoplasmosis it was 25.7%, higher among the oldest and foreign women; IgG for CMV was positive in 62.4%, no influence of age was found. VDRL was reactive in 0.5%;...
Marques, F; Silva, IV; Branco, C; Paiva, M; Cunha, F
Silva, AV; Morais, RB; Francisco, T; Dessal, S; Pastilha, P; Cunha, F
Introduction: Kerion celsi is the rare and inﬂ ammatory form of tinea capitis which is caused by dermatophyte fungi. Diagnosis
is not easy due to the delay in cultural examination and the need to consider various etiologies in the differential diagnosis.
Treatment must be prolonged and requires systemic antifungals.
Since griseofulvin was discontinued in the Portuguese market, it has been necessary to consider therapeutic alternatives.
Salva, I; Silva, IV; Cunha, F
Epstein-Barr virus infection is common in children, usually presenting as infectious mononucleosis, including fever, tonsillitis and lymphadenopathy associated with self-resolving increase in transaminases. Cholestasis is rare in children with only a few cases reported but it was described in up to 55% of the adult population affected. We present a case of a 6-year-old boy with fever, vomiting and choluria. The physical examination showed hepatomegaly and jaundice and was otherwise unremarkable. The laboratory studies revealed increased transaminases (aspartate aminotransferase 97 U/L, alanine aminotransferase 166 U/L), hyperbilirubinaemia (total bilirubin 3.2 mg/dL, direct bilirubin 2.89 mg/dL) and increased γ-glutamyl transpeptidase (114 mg/dL)....
Ferreira, PS; Rodrigues, P; Peres, A; Roque do Vale, P; Casimiro, A; Cunha, F
Infective Endocarditis is caused by bacteria or fungi involving the heart or the great vessels (Endarteritis). It is a rare and potentially ominous disease, with increasing incidence. Despite technological advances it remains difficult to diagnose and treat, particularly in children below two years. Congenital heart disease is the main risk factor for Infective Endocarditis in children. A patent ductus arteriosus clinically silent is infrequently implied. Over two-month-old Streptococci spp and Staphylococcus aureus are the main agents, responsible for 62-77% of cases. Gram negative rods count for 4-6%, being Klebsiella pneumoniae a rare pathogen. The authors report a case of a...