Singh, Sally J.; SPRUIT, Martijn A.; Troosters, Thierry; Holland, Anne E.
WENS, Inez; Dalgas, Ulrik; VANDENABEELE, Frank; Krekels, Maartje; Grevendonk, Lotte; EIJNDE, OP 'T Bert
Background: The impact of multiple sclerosis (MS) on skeletal muscle characteristics, such as muscle fiber cross sectional
area (CSA), fiber type proportion, muscle strength and whole muscle mass, remains conflicting.
Methods: In this cross sectional study, body composition and muscle strength of the quadriceps were assessed in 34 MS
(EDSS: 2.560.19) patients and 18 matched healthy controls (HC). Hereafter a muscle biopsy (m.vastus lateralis) was taken.
Results: Compared to HC, mean muscle fiber CSA of all fibers, as well as CSA of type I, II and IIa fibers were smaller and
muscle strength of the quadriceps was lower in MS patients. Whole body composition was...
Heesen, Christoph; Bruce, Jared; FEYS, Peter; Sastre-Garriga, Jaume; Solari, Alessandra; Eliasson, Lina; Matthews, Vicki; Hausmann, Bettina; Ross, Amy Perrin; Asano, Miho; Imonen-Charalambous, Kaisa; K??pke, Sascha; Clyne, Wendy; Bissell, Paul
Background: Adherence to medical interventions is a global problem. With an increasing amount of partially effective but expensive drug treatments adherence is increasingly relevant in multiple sclerosis (MS). Perceived lack of efficacy and side effects as well as neuropsychiatric factors such as forgetfulness, fatigue and depression are major determinants. However, research on adherence to behavioural interventions as part of rehabilitative interventions has only rarely been studied. Methods: In a one-day meeting health researchers as well as patient representatives and other stakeholders discussed adherence issues in MS and developed a general draft research agenda within a focus group session. Results: The...
MATHEVE, Thomas; Timmermans, Annick
The aim of this systematic review is (1) to provide an overview of the available Technology Supported Exercise Therapy (TSET) programs for low back pain, and (2) to assess the effectiveness of TSET compared to other forms of rehabilitation, placebo interventions or no treatment.
METHODS Electronic databases (Pubmed, Embase, Cochrane Central Register of Controlled Trials, PEDro, IEEE and ACM) were searched until January 2014. Randomized controlled trials comparing TSET to other forms of rehabilitation, placebo interventions or no treatment were included. Further inclusion criteria were: (1) patients with low back pain of musculoskeletal origin, (2) adult population, (3) technologies with an...
Bervoets, Liene; Van Noten, Caroline; Van Roosbroeck, Sofie; Hansen, Dominique; Van Hoorenbeeck, Kim; Verheyen, Els; Van Hal, Guido; Vankerckhoven, Vanessa
This study was designed to validate the Dutch Physical Activity Questionnaires for Children (PAQ-C) and Adolescents (PAQ-A).
After adjustment of the original Canadian PAQ-C and PAQ-A (i.e. translation/backtranslation and evaluation by expert committee), content validity of both PAQs was assessed and calculated using item-level (I-CVI) and scale-level (S-CVI) content validity indexes. Inter-item and inter-rater reliability of 196 PAQ-C and 95 PAQ-A filled in by both children or adolescents and their parent, were evaluated. Inter-item reliability was calculated by
Cronbach’s alpha(α) and inter-rater reliability was examined by percent observed agreement and weighted kappa(κ). Concurrent validity of PAQ-A was examined in a subsample of...
STEVENS, An; HANSEN, Dominique; HERBOTS, Lieven; WENS, Inez; CREEMERS, An; DENDALE, Paul; EIJNDE, Bert O.
PURPOSE: Chronic heart failure (CHF) patients often present with (pre)diabetes, which negatively influences prognosis. Unlike the proven effect of exercise on glucose regulation in the general population, its effect in CHF is unclear. Therefore, this study aimed at investigating the effect of exercise training on glucose regulation in stable CHF patients.
METHODS: Twenty-two CHF patients were randomized into training (EX,n = 15) and control (CON, n = 7) groups. Before and after a 12-week training intervention involving endurance and resistance training, glucose tolerance (2-hour oral glucose tolerance test), exercise tolerance (cardiopulmonary exercise test), muscle strength (isokinetic dynamometer), heart function (echocardiography), glycated...
Vaes, Anouk W.; Garcia-Aymerich, Judith; Marott, Jacob L.; Benet, Martha; Groenen, Miriam T.J.; Schnohr, Peter; Franssen, Frits M.E.; Vestbo, Jorgen; Wouters, Emiel F.M.; Lange, Peter; SPRUIT, Martijn A.
Little is known about changes in physical activity in subjects with chronic obstructive pulmonary disease (COPD) and its impact on mortality. Therefore, we aimed to study changes in physical activity in subjects with and without COPD and the impact of physical activity on mortality risk. Subjects from the Copenhagen City Heart Study with at least two consecutive examinations were selected. Each examination included a self-administered questionnaire and clinical examination. 1270 COPD subjects and 8734 subjects without COPD (forced expiratory volume in 1 s 67??18 and 91??15% predicted, respectively) were included. COPD subjects with moderate or high baseline physical activity who...
Holland, Anne E.; SPRUIT, Martijn A.; Troosters, Thierry; Puhan, Milo A.; Pepin, Veronique; Saey, Didier; McCormack, Meredith C.; Carlin, Brian W.; Sciurba, Frank C.; Pitta, Fabio; Wanger, Jack; MacIntyre, Neil; Kaminsky, David A.; Culver, Bruce H.; Revill, Sue M.; Hernandes, Nidia A.; Andrianopoulos, Vasileios; Camillo, Carlos A.; Mitchell, Katy E.; Lee, Ann L.; Hill, Catherine J.; Singh, Sally J.
Field walking tests are commonly employed to evaluate exercise capacity, assess prognosis and evaluate treatment response in chronic respiratory diseases. In recent years, there has been a wealth of new literature pertinent to the conduct of the 6-min walk test (6MWT), and a growing evidence base describing the incremental and endurance shuttle walk tests (ISWT and ESWT, respectively). The aim of this document is to describe the standard operating procedures for the 6MWT, ISWT and ESWT, which can be consistently employed by clinicians and researchers. The Technical Standard was developed by a multidisciplinary and international group of clinicians and researchers...
Singh, Sally J.; Puhan, Milo A.; Andrianopoulos, Vasileios; Hernandes, Nidia A.; Mitchell, Katy E.; Hill, Catherine J.; Lee, Ann L.; Camillo, Carlos A.; Troosters, Thierry; SPRUIT, Martijn A.; Carlin, Brian W.; Wanger, Jack; Pepin, Veronique; Saey, Didier; Pitta, Fabio; Kaminsky, David A.; McCormack, Meredith C.; MacIntyre, Neil; Culver, Bruce H.; Scuirba, Frank C.; Revill, Sue M.; Delafosse, V.; Holland, Anne E.
This systematic review examined the measurement properties of the 6-min walk test (6MWT), incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT) in adults with chronic respiratory disease. Studies that report the evaluation or use of the 6MWT, ISWT or ESWT were included. We searched electronic databases for studies published between January 2000 and September 2013. The 6-min walking distance (6MWD) is a reliable measure (intra-class correlation coefficients ranged from 0.82 to 0.99 in seven studies). There is a learning effect, with greater distance walked on the second test (pooled mean improvement of 26 m in 13 studies)....
Andrianopoulos, Vasilis; Klijn, Peter; Franssen, Frits M.E.; SPRUIT, Martijn A.
Exercise training remains a cornerstone of pulmonary rehabilitation (PR) in patients with chronic respiratory disease. The choice of type of exercise training depends on the physiologic requirements and goals of the individual patient as well as the available equipment at the PR center. Current evidence suggests that, at ground walking exercise training, Nordic walking exercise training, resistance training, water-based exercise training, tai chi, and nonlinear periodized exercise are all feasible and effective in (subgroups) of patients with chronic obstructive pulmonary disease. In turn, these exercise training modalities can be considered as part of a comprehensive, interdisciplinary PR program.
SPRUIT, Martijn A.
Pulmonary rehabilitation is a comprehensive intervention designed to improve the physical and psychological condition of people with chronic respiratory disease and promote the long-term adherence to health-enhancing behaviours. During the 2013 European Respiratory Society Annual Congress in Barcelona, Spain, a Clinical Year in Review session was held focusing on the latest developments in pulmonary rehabilitation. This review summarises some of the main findings of peer-reviewed articles focusing on pulmonary rehabilitation that were published in the 12 months prior to the 2013 Annual Congress.
Watz, Henrik; Pitta, Fabio; Rochester, Carolyn L.; Garcia-Aymerich, Judith; ZuWallack, Richard; Troosters, Thierry; Vaes, Anouk W.; Puhan, Milo A.; Jehn, Melissa; Polkey, Michael I.; Vogiatzis, Ioannis; Clini, Enrico M.; Toth, Michael; Gimeno-Santos, Elena; Waschki, Benjamin; Esteban, Cristobal; Hayot, Maurice; Casaburi, Richard; Porszasz, Janos; McAuley, Edward; Singh, Sally J.; Langer, Daniel; Wouters, Emiel F.M.; Magnussen, Helgo; SPRUIT, Martijn A.
This European Respiratory Society (ERS) statement provides a comprehensive overview on physical activity in patients with chronic obstructive pulmonary disease (COPD). A multidisciplinary Task Force of experts representing the ERS Scientific Group 01.02 “Rehabilitation and Chronic Care” determined the overall scope of this statement through consensus. Focused literature reviews were conducted in key topic areas and the final content of this Statement was agreed upon by all members.
The current knowledge regarding physical activity in COPD is presented, including the definition of physical activity, the consequences of physical inactivity on lung function decline and COPD incidence, physical activity assessment, prevalence...
Frederix, Ines; Van Driessche, Niels; Laenen, Valerie; Loverix, Liselore; Hansen, Dominique; Dendale, Paul
Purpose: The purpose of the study was to evaluate whether the addition of a motion sensor with automated feed-back by email or SMS to cardiac rehabilitation (CR) could result in improved health conditions of coronary artery disease (CAD) patients.
Methods: 80 CAD patients in phase II of the CR program were included in this RCT after admission for PCI or CABG. Patients with a defibrillator, important arrhythmias or severe heart failure (NYHA class III and IV) were excluded from the trial. The patients in the intervention group (n = 40) were asked to wear the motion sensor continuously during the day...
Frederix, Ines; Van Driessche, Niels; DENDALE, Paul; Hansen, Dominique; Berger, Jan; Bonne, Kim; Alders, Toon
Internet; telerehabilitation; coronary artery disease
BAERT, Ilse; Smedal, T.; Freeman, J.; Dalgas, U.; Romberg, A.; Kalron, A.; Conyers, H.; Elorriaga, I.; Gebara, B.; Gumse, J.; Heric, A.; Jensen, E.; Jones, K.; de Noordhout, B. M.; Martic, A.; Normann, B.; Eijnde, B. O.; Rasova, K.; Santoyo Medina, C.; FEYS, Peter
WENS, Inez; Dalgas, U.; Deckx, N.; Cools, N.; Op 't Eijnde, Bert
Based on current literature, it is not clear if multiple sclerosis (MS) patients are at increased risk to develop impaired glucose tolerance (IGT). Eighty-one MS patients and 45 healthy controls (HC) performed an oral glucose tolerance test. IGT was defined as a fasting glucose concentration of 6.1-6.9 mmol/l and two-hour post-load glucose of 7.8-11.1 mmol/l. The prevalence of impaired fasting glucose concentrations (17% vs 2%) and IGT (11% vs 0%) was higher in MS patients than HC. Accordingly, the areas under the glucose and insulin curves were higher in MS patients. The current study demonstrates an elevated IGT-prevalence in MS.
Christensen, D. L.; BAERT, Ilse; FEYS, Peter; Dalgas, U.
DOLEZALOVA, Vendula; BAERT, Ilse; Dalgas, U.; Romberg, A.; Bethoux, F.; Gebara, B.; Santoyo Medina, C.; Maamagi, Heigo; Rasova, K.; Maertens, B.; Knuts, K.; Skjerbaek, A.; Jensen, E.; FEYS, Peter
Sampson, P.; Buchanon, S.; Coote, S.; Demain, S.; FEYS, Peter; Freeman, C.; Meadmore, K.; Hughes, A. -M.
VANVUCHELEN, Marleen; TANT, Mark; JONGEN, Ellen; ROSS, Veerle
Er gaat geen dag voorbij of er gebeurt wat op de Belgische autosnelwegen. Ongevallen, hopelijk enkel met blikschade, zijn te wijten aan zoveel mogelijke oorzaken: onoplettendheid bij een bestuurder, plotse manoevers, een andere inschatting van de veiligheid... Maar hoe zit het dan wanneer daar ook nog eens autisme bij komt? De Universiteit van Hasselt en het Belgisch Instituut voor Verkeersveiligheid sloegen de handen in mekaar en onderzochten de factor autisme in het verkeer en het behalen van een rijbewijs.