Recursos de colección

TDX/TDR Tesis Doctorales en Red (79.696 recursos)

TDR (Tesis Doctorales en Red) es un repositorio cooperativo que contiene, en formato digital, tesis doctorales leídas en las universidades de Catalunya y otras comunidades autónomas. La consulta de las tesis es de acceso libre y permite realizar búsquedas en el texto completo de las tesis, por autor/a, director/a, título, materia de la tesis, universidad y departamento donde se haya leído, año de defensa, etc.

Departament de Ciències Experimentals i de la Salut

Mostrando recursos 1 - 4 de 4

  1. Neurobiological links between depression and drug dependence

    Gracia Rubio, Irene, 1986-
    Early life experiences play a key role in brain function and behaviour. Maternal separation produced negative early life experiences that induce emotional alterations. Contrary, the communal nest has been proposed as a protective model that may reduce the vulnerability of individuals to suffer psychiatric disorders. Moreover, early-life stress enhances the vulnerability to develop substance use disorders, principally during adolescence. Hence, depressive states are associated with drug use disorders and abuse vulnerability since depressed patients could consume drugs to alleviate their symptoms. Our results lead us to propose that detrimental early life events such as maternal neglect reproduces most of the...
    (application/pdf; 297 p.) - 16-mar-2018

  2. Physical activity as a crucial patient-reported outcome in Chronic Obstructive Pulmonary Disease

    Gimeno Santos, Elena, 1980-
    Physical inactivity is a hallmark of Chronic Obstructive Pulmonary Disease (COPD), which relates to outcomes relevant for patients and healthcare providers. Despite its importance, no patient reported outcome (PRO) instrument exists that captures physical activity that maximally reflects the experience of patients with COPD. The aim of the PROactive project is to develop, validate and use two PRO instruments (one for daily assessment, while the second as a clinical measure) to measure physical activity in COPD, researching and incorporating all dimensions of physical activity reported by patients. These tools are developed in accordance with the guidelines from the Food and...
    (application/pdf; 305 p.) - 11-may-2018

  3. Caracterización de los pacientes hospitalizados por primera vez por exacerbación de la Enfermedad Pulmonar Obstructiva Crónica

    Balcells Vilarnau, Eva, 1967-
    Introducción: Hay poca información sobre la primera hospitalización por exacerbación de la Enfermedad Pulmonar Obstructiva Crónica (EPOC), a pesar de ser un evento importante en la historia natural de esta enfermedad. El objetivo de esta tesis fue estudiar el perfil clínico de los pacientes hospitalizados por primera vez por una exacerbación de la EPOC, con especial atención a la comorbilidad psicológica y su relación con la calidad relacionada con la salud de la vida (CVRS), y también investigar el grado y las características del infradiagnóstico de la EPOC, en este momento. Métodos: El estudio incluyó una amplia muestra de pacientes hospitalizados por...
    (application/pdf; 115 p.) - 11-may-2018

  4. Measure and effect of diet in chronic obstructive pulmonary disease

    Batlle Garcia, Jordi de, 1981-
    Background and objectives: Recent research has shown an association between a healthy diet and reduced chronic obstructive pulmonary disease (COPD) incidence. However, the potential role of diet in COPD prognosis is unknown. This thesis aimed to describe the characteristics of diet in COPD patients and to estimate its association with the disease evolution, in terms of pathophysiological impairment and hospitalizations. A secondary objective was to study the role of diet in asthma, as a COPDrelated phenotype. Methods: A dietary ancillary protocol was included in a well phenotyped cohort of 342 COPD patients recruited during their first admission for a COPD exacerbation in Spain. Dietary data of the last 2 years was assessed...
    (application/pdf; 182 p.) - 11-may-2018

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