Seca, Ana M. L.; Grigore, Alice; Pinto, Diana C. G. A.; Silva, Artur M. S.
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Inula comprises more than one hundred species widespread in temperate regions of Europe and Asia. Uses of this genus as herbal medicines have been first recorded by the Greek and Roman ancient physicians. In the Chinese Pharmacopoeia, from the 20 Inula spp. distributed in China, three are used as Traditional Chinese medicines, named Tumuxiang, Xuanfuhua and Jinfeicao. These medicines are used as expectorants, antitussives, diaphoretics, antiemetics, and bactericides. Moreover, Inula helenium L. which is mentioned in Minoan, Mycenaean, Egyptian/Assyrian pharmacotherapy and Chilandar Medical Codex, is good to treat neoplasm, wound, freckles and dandruff. Many other Inula...
Isca, Vera M. S.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Helena; Silva, Artur M. S.
Salicornia ramosissima J. Woods is considered, in the Iberian Peninsula and France, a gourmet product. Nevertheless, is one of the less studied Salicornia species. In this work, GC-MS was employed to, for the first time; fully characterise the lipophilic profile of S. ramosissima and to assess the effect of natural and extra irrigation in that profile. The obtained data showed esterified and free fatty acids, fatty alcohol, sterols, alkanes and aromatic acid derivatives, being palmitic acid, tetracosanol and octacosanol the most abundant compounds. The extra irrigation increases significantly (P < 0.001) the content of esterified lipophilic compounds. Stigmastanol, 24-ethyl-δ(22)-coprostenol, several...
Seca, Ana M. L.; Leal, Stephanie B.; Pinto, Diana C. G. A.; Barreto, Maria do Carmo; Silva, Artur M. S.
Natural and synthetic xanthone derivatives are well-known for their ability to act as antioxidants and/or enzyme inhibitors. This paper aims to present a successful synthetic methodology towards xanthenedione derivatives and the study of their aromatization to xanthones. Additionally their ability to reduce Fe(III), to scavenge DPPH radicals and to inhibit AChE was evaluated. The results demonstrated that xanthenedione derivative 5e, bearing a catechol unit, showed higher reduction capacity than BHT and similar to quercetin, strong DPPH scavenging activity (EC50 = 3.79 Â± 0.06 Î¼M) and it was also showed to be a potent AChEI (IC50 = 31.0 Â± 0.09 Î¼M)...
Lima, Ana; Ferin, Rita; Baptista, José; Pavão, Maria Leonor
Copyright © 2014 Ana Lima et al. This is an open access article distributed under the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Ferin, Rita; Pavão, Maria Leonor; Baptista, José
Copyright © 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
Cymbron, Teresa; Raposo, Mafalda; Kazachkova, Nadia; Bettencourt, Conceição; Silva, Francisca; Santos, Cristina; Dahmani, Yahya; Lourenço, Paula C.; Ferin, Rita; Pavão, Maria Leonor; Lima, Manuela
Copyright © 2011 Informa UK Ltd.