Recursos de colección

Repositorio da Universidade dos Açores (8.391 recursos)

O Repositório Institucional da Universidade dos Açores desenvolvido no âmbito do projecto RCAAP.

DCE - Artigos em Revistas Internacionais / Articles in International Journals

Mostrando recursos 1 - 20 de 99

  1. Reasserting curriculum design through virtual learning environments : The case of MAPE

    Sousa, Francisco
    MAPE is a curricular model for virtual learning at the University of the Azores, Portugal. After being used for teaching Curriculum Theory and Development through e-learning and b-learning, this model has been, in the academic year 2014/15, extended to other courses. Besides describing the model and explaining its evolution, this paper reports a study of its implementation, for the first time, by more than one instructor. Accordingly, the main objective of the study is to test the MAPE model on a multi-course level. In this specific case, the model has been implemented in eight courses from the specialization program in...

  2. Expanding Areas of Influence at Azores University : Virtual Campus, Regional Clusters and Points of Presence

    Roth, Rogério
    The paper draws on findings from the research “Implementation Strategies and Development of an Open and Distance Education System for the University of the Azores”, funded by the European Social Fund. The main objective of this research was to observe the recent events related to likely paradigm shift in the educational area and propose to UAC the adoption of solutions that can, at the same time, correct implementations already carried out in previous experiments and respond to these new challenges. http://hdl.handle.net/10400.3/2327

  3. Support Structures to the Teaching Mediated by Technologies

    Roth, Rogério
    This paper is part of the results from the project “Implementation Strategies and Development of an Open and Distance Education System for the University of the Azores” funded by the European Social Fund. The main objective of this research was to observe the recent events related to the likely paradigm shift in the educational field and propose to the UAC the adoption of solutions that can, correct implementations already made, and at the same time meet their internal demands and respond to these new challenges. http://hdl.handle.net/10400.3/2327

  4. Emotional, cognitive and behavioral reactions to paranoia in clinical and nonclinical population

    Carvalho, Célia; Pinto-Gouveia, José; Peixoto, Ermelindo; Motta, Carolina
    BACKGROUND: Paranoia is a disruptive belief that can vary across a continuum, ranging from persecutory delusions presented in clinical settings to paranoid cognitions that are highly prevalent in the general population. The literature suggests that paranoid thoughts derive from the activation of a paranoid schema or information processing biases that can be sensitive to socially ambiguous stimuli and influence the processing of threatening situations. METHOD: Four groups (Schizophrenic participants in active psychotic phases, n=6; stable participants in remission, n=30; participants’ relatives, n=32; and healthy controls, n=64) were assessed with self-report questionnaires to determine how the reactions to paranoia of clinical...

  5. Intervir através da educação física na coeducação : realidade ou intenção?

    Condessa, Isabel; Anastácio, Zélia
    Intervir de forma consciente e organizada em prol da promoção da igualdade de oportunidades na escola tem sido, nas últimas décadas, um dos propósitos da Educação Física (EF) na Europa. Através das rotinas e das oportunidades que se proporcionam, rapazes e raparigas têm acesso a uma prática de atividade física e desportiva (AFD) que lhes possibilita aperfeiçoar capacidades, competências e atitudes. O contributo da EF na educação é de um valor significativo, viabilizando às crianças e jovens construir a sua imagem corporal e os estereótipos de género, desenvolver afectos e emoções, cultivar a sua relação com os outros, criar capacidades...

  6. Influence of Family and Childhood Memories in the Development and Manifestation of Paranoid Ideation

    Carvalho, Célia; Motta, Carolina; Pinto-Gouveia, José; Peixoto, Ermelindo Bernardo
    Several studies point out to the influence of social experiences on perceptions of the environment and others in cognitive functioning and different aspects of psychopathology. The current study aimed at studying the influence of the psychosocial risk factors in a mixed sample of participants from the general population and affected by paranoid schizophrenia. The extent to which the existence of negative life events and events that are threatening to the inner models of the self (i.e., history of maltreatment, physical, social or psychological abuse) or the memories of these traumatic events occurring during childhood are related to the existence of...

  7. The Clinical Interview for Psychotic Disorders (CIPD) : development and expert evaluation

    Martins, Maria J.; Carvalho, Célia; Castilho, Paula; Pereira, Ana Telma; Macedo, António
    Background: New treatment approaches for psychosis indicate that effective interventions require a therapeutic focus on emotional regulation, cognitive appraisals, and functioning. Efficacy of psychotherapeutic interventions’ evaluation has changed from exclusively assessing symptom frequency/severity to a comprehensive and functional assessment of interference, functioning, and the relationship people have with symptoms. This shift led to new needs in clinical assessment. This study aimed to develop and submit to expert evaluation a new clinical interview for psychotic disorders which considers the new needs of the field. Methods: CIPD was developed by a multidisciplinary team considering the DSM-5 criteria for psychotic and affective disorders. Relevant information...

  8. Rare chromosomal deletions and duplications increase risk of schizophrenia

    Craddock, N. J.; Gill, M.; Hultman, C. M.; Lichtenstein, P.; McQuillin, A.; Pato, Carlos N.; Ruderfer, D. M.; Owen, M. J.; St Clair, David; Sullivan, P. F.; Sklar, P.; Purcell, S. M.; Stone, J. L; Korn, Joshua; Macgregor, S.; Morris, D. W.; O'Dushlaine, C. T.; Daly, M. J.; Visscher, P. M.; Holmans, P. A.; Scolnick, E: M.; Williams, N. M.; Georgieva, L.; Nikolov, I.; Norton, N.; Williams, H.; Toncheva, D.; Milanova, V.; Thelander, Emma F.; Sullivan, P. F.; Kenny, E.; Waddington, John L.; Choudhury, K.; Datta, S.; Pimm, J.; Thirumalai, S.; Puri, V.; Krasucki, R.; Lawrence, J.; Quested, D.; Bass, N.; Curtis, David; Gurling, H.; Crombie, C.; Fraser, G.; Kwan, Soh Leh; Walker, N.; Muir, W. J.; McGhee, K. A.; Pickard, B.; Malloy, P.; Maclean, A. W.; Van Beck, Margaret; Visscher, P. M.; Pato, Michele T.; Medeiros, Helena; Middleton, Frank A.; Carvalho, Célia; Morley, C.; Fanous, Ayman H.; Conti, D.; Knowles, James A.; Ferreira, Carlos Paz; Macedo, António; Azevedo, Maria H.; McCarroll, Steve A.; Daly, M. J.; Chambert, Kimberly; Gates, Casey
    Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73–90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved are not understood. Copy number variants (CNVs) have been identified in individual patients with schizophrenia and also in neurodevelopmental disorders, but large-scale genome-wide surveys have not been performed. Here we report a genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls, using high-density microarrays. For CNVs that were observed in less than 1% of the sample and were more...

  9. Genomewide Linkage Analysis of Bipolar Disorder by Use of a High Density Single-Nucleotide–Polymorphism (SNP) Genotyping Assay : A Comparison with Microsatellite Marker Assays and Finding of Significant linkage to Chromosome 6q22

    Middleton, Frank A.; Pato, Michele T.; Gentile, Karen; Morley, C. P.; Zhao, X.; Eisener, A. F.; Brown, A.; Petryshen, T. L.; Kirby, A. N.; Medeiros, Helena; Carvalho, Célia; Macedo, António; Dourado, A.; Coelho, I.; Valente, J.; Soares, M. J.; Ferreira, Carlos Paz; Lei, M.; Azevedo, Maria H.; Kennedy, J. L.; Daly, M. J.; Sklar, P.; Pato, Carlos N.
    We performed a linkage analysis on 25 extended multiplex Portuguese families segregating for bipolar disorder, by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay, the GeneChip Human Mapping 10K Array (HMA10K). Of these families, 12 were used for a direct comparison of the HMA10K with the traditional 10-cM microsatellite marker set and the more dense 4-cM marker set. This comparative analysis indicated the presence of significant linkage peaks in the SNP assay in chromosomal regions characterized by poor coverage and low information content on the microsatellite assays. The HMA10K provided consistently high information and enhanced coverage throughout these regions. Across...

  10. Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis

    Sklar, P.; Pato, Michele T.; Kirby, A. N.; Petryshen, T. L.; Medeiros, Helena; Carvalho, Célia; Macedo, António; Dourado, A.; Coelho, I.; Valente, J.; Soares, M. J.; Ferreira, Carlos Paz; Lei, M.; Verner, A.; Hudson, T. J.; Morley, C. P.; Kennedy, J. L.; Azevedo, Maria H.; Lander, E.; Daly, M. J.; Pato, Carlos N.
    Schizophrenia is a common psychiatric disorder with a complex genetic etiology. To understand the genetic basis of this syndrome in Portuguese Island populations, we performed a genome-wide scan of 29 families with schizophrenia, which identified a single region on 5q31-5q35 with strong linkage (NPL=3.09, P=0.0012 at D5S820). Empirical simulations set a genome-wide threshold of NPL=3.10 for significant linkage. Additional support for this locus in schizophrenia comes from higher-density mapping and mapping of 11 additional families. The combined set of 40 families had a peak NPL=3.28 (P=0.00066) at markers D5S2112-D5S820. These data and previous linkage findings from other investigators provide strong...

  11. Common polygenic variation contributes to risk of schizophrenia and bipolardisorder

    Purcell, S. M.; Wray, N. R.; Stone, J. L.; Visscher, P. M.; O'Donovan, M. C.; Sullivan, P. F.; Sklar, P.; Leader, S. M.; Ruderfer, D. M.; McQuillin, A.; Morris, D. W.; O'Dushlaine, C. T.; Corvin, A.; Holmans, P. A.; Macgregor, S.; Gurling, H.; Blackwood, D. H.; Craddock, N. J.; Gill, M.; Hultman, C. M.; Kirov, G. K.; Lichtenstein, P.; Muir, W. J.; Owen, M. J.; Pato, Carlos N.; Scolnick, E. M.; St Clair, D.; Williams, N. M.; Georgieva, L.; Nikolov, I.; Norton, N.; Williams, H.; Toncheva, D.; Milanova, V.; Helander, E. F.; Kenny, E.; Quinn, E. M.; Choudhury, K.; Datta, S.; Pimm, J.; Thirumalai, S.; Puri, V.; Krasucki, R.; Lawrence, J.; Quested, D.; Bass, N.; Crombie, C.; Fraser, G.; Leh, K. S.; Walker, N.; Black-wood, D. H.; McGhee, K. A.; Pickard, B.; Malloy, P.; Maclean, A. W.; Van Beck, M.; Pato, Michele T.; Medeiros, Helena; Middleton, Frank A.; Carvalho, Célia; Morley, C.; Fanous, Ayman H.; Conti, D.; Knowles, James A.; Ferreira, Carlos Paz; Macedo, António; Kirby, A. N.; Ferreira, M. A.; Daly, M. J.; Cham-bert, K.; Kuruvilla, F.; Gabriel, S. B.; Ardlie, K.; Moran, J. L.
    Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%. We performed a genome-wide association study of 3,322 European individuals with schizophrenia and 3,587 controls. Here we show, using two analytic approaches, the extent to which common genetic variation underlies the risk of schizophrenia. First, we implicate the major histocompatibility complex. Second, we provide molecular genetic evidence for a substantial polygenic component to the risk of schizophrenia involving thousands of common alleles of very small effect. We show that this component also contributes...

  12. Genome-wide scan in Portuguese Island families implicates multiple loci in bipolar disorder : fine mapping adds support on chromosomes 6 and 11

    Pato, Carlos N.; Pato, Michele T.; Kirby, A. N.; Petryshen, T. L.; Medeiros, Helena; Carvalho, Célia; Macedo, António; Dourado, A.; Coelho, I.; Valente, J.; Soares, M. J.; Ferreira, Carlos Paz; Lei, M.; Verner, A.; Hudson, T. J.; Morley, C. P.; Kennedy, J. L; Azevedo, Maria H.; Daly, M. J.; Sklar, P.
    As part of an extensive study in the Portuguese Island population of families with multiple patients suffering from bipolar disorder and schizophrenia, we performed an initial genome-wide scan of 16 extended families with bipolar disorder that identified three regions on chromosomes 2, 11, and 19 with genome-wide suggestive linkage and several other regions, including chromosome 6q, also approached suggestive levels of significance. Dick et al. [2003: Am J Hum Genet 73:107-114] recently reported in a study of 250 families with bipolar disorder a maxLOD score of 3.61 near marker D6S1021 on chromosome 6q. This study replicates this finding having detected...

  13. Development and Validation of the Response to Stressful Situations Scale in the General Population

    Carvalho, Célia; Motta, Carolina; Sousa, Marina; Cabral, Joana; Carvalho, Ana Luisa; Peixoto, Ermelindo Bernardo
    The aim of the current study was to develop and validate a Response to Stressful Situations Scale (RSSS) for the Portuguese population. This scale assesses the degree of stress experienced in scenarios that can constitute positive, negative and more neutral stressors, and also describes the physiological, emotional and behavioral reactions to those events according to their intensity. These scenarios include typical stressor scenarios relevant to patients with schizophrenia, which are currently absent from most scales, assessing specific risks that these stressors may bring on subjects, which may prove useful in non-clinical and clinical populations (i.e. Patients with mood or anxiety...

  14. Development and Validation of the Response to Stressful Situations Scale in the General Population

    Carvalho, Célia; Motta, Carolina; Sousa, Marina; Cabral, Joana; Carvalho, Ana Luisa; Peixoto, Ermelindo Bernardo
    The aim of the current study was to develop and validate a Response to Stressful Situations Scale (RSSS) for the Portuguese population. This scale assesses the degree of stress experienced in scenarios that can constitute positive, negative and more neutral stressors, and also describes the physiological, emotional and behavioral reactions to those events according to their intensity. These scenarios include typical stressor scenarios relevant to patients with schizophrenia, which are currently absent from most scales, assessing specific risks that these stressors may bring on subjects, which may prove useful in non-clinical and clinical populations (i.e. Patients with mood or anxiety...

  15. Hallucinatory Activity in Schizophrenia : The Relationship with Childhood Memories, Submissive Behavior, Social Comparison, and Depression

    Carvalho, Célia; Motta, Carolina; Pinto-Gouveia, José; Peixoto, Ermelindo Bernardo
    Auditory hallucinations among the most invalidating and distressing experiences reported by patients diagnosed with schizophrenia, leading to feelings of powerlessness and helplessness towards their illness. In more severe cases, these auditory hallucinations can take the form of commanding voices, which are often related to high suicidality rates in these patients. Several authors propose that the meanings attributed to the hallucinatory experience, rather than characteristics like form and content, can be determinant in patients’ reactions to hallucinatory activity, particularly in the case of voice-hearing experiences. In this study, patients diagnosed with paranoid schizophrenia presenting auditory hallucinations were studied. Multiple regression analyses...

  16. Hallucinatory Activity in Schizophrenia : The Relationship with Childhood Memories, Submissive Behavior, Social Comparison, and Depression

    Carvalho, Célia; Motta, Carolina; Pinto-Gouveia, José; Peixoto, Ermelindo Bernardo
    Auditory hallucinations among the most invalidating and distressing experiences reported by patients diagnosed with schizophrenia, leading to feelings of powerlessness and helplessness towards their illness. In more severe cases, these auditory hallucinations can take the form of commanding voices, which are often related to high suicidality rates in these patients. Several authors propose that the meanings attributed to the hallucinatory experience, rather than characteristics like form and content, can be determinant in patients’ reactions to hallucinatory activity, particularly in the case of voice-hearing experiences. In this study, patients diagnosed with paranoid schizophrenia presenting auditory hallucinations were studied. Multiple regression analyses...

  17. Characterization and Predictors of Community Integration of People with Psychiatric Problems : Comparisons with the General Population

    Cabral, Joana Moura; Carvalho, Célia; Motta, Carolina; Sousa, Marina
    Community integration is a construct that an increasing body of research has shown to have a significant impact on the wellbeing and recovery of people with psychiatric problems. However, there are few studies that explore which factors can be associated and predict community integration. Moreover, community integration has been mostly studied in minority groups, and current literature on the definition and manifestation of community integration in the general population is scarcer. Thus, the current study aims to characterize community integration and explore possible predictor variables in a sample of participants with psychiatric problems (PP, N=183) and a sample of participants...

  18. Characterization and Predictors of Community Integration of People with Psychiatric Problems : Comparisons with the General Population

    Cabral, Joana Moura; Carvalho, Célia; Motta, Carolina; Sousa, Marina
    Community integration is a construct that an increasing body of research has shown to have a significant impact on the wellbeing and recovery of people with psychiatric problems. However, there are few studies that explore which factors can be associated and predict community integration. Moreover, community integration has been mostly studied in minority groups, and current literature on the definition and manifestation of community integration in the general population is scarcer. Thus, the current study aims to characterize community integration and explore possible predictor variables in a sample of participants with psychiatric problems (PP, N=183) and a sample of participants...

  19. Paranoia as a continuum in the population

    Carvalho, Célia; Pinto-Gouveia, José; Peixoto, Ermelindo Bernardo; Motta, Carolina
    Paranoid beliefs, though key to the diagnosis of paranoid schizophrenia, are not exclusively seen in patients suffering from this psychopathology and exist in less severe forms across different populations. Evaluating these symptoms as a continuum may be more interesting for the understanding of paranoia rather than the dichotomous approach to this kind of ideation. The main goal of the current research is to assess how paranoid beliefs are present across different populations. Using the Portuguese versions of the General Paranoia Scale and the Paranoia checklist, we compared the endorsement of paranoid beliefs in 187 subjects (64 healthy controls from the...

  20. Paranoia as a continuum in the population

    Carvalho, Célia; Pinto-Gouveia, José; Peixoto, Ermelindo Bernardo; Motta, Carolina
    Paranoid beliefs, though key to the diagnosis of paranoid schizophrenia, are not exclusively seen in patients suffering from this psychopathology and exist in less severe forms across different populations. Evaluating these symptoms as a continuum may be more interesting for the understanding of paranoia rather than the dichotomous approach to this kind of ideation. The main goal of the current research is to assess how paranoid beliefs are present across different populations. Using the Portuguese versions of the General Paranoia Scale and the Paranoia checklist, we compared the endorsement of paranoid beliefs in 187 subjects (64 healthy controls from the...

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