Mostrando recursos 1 - 10 de 10

  1. Endoscopic therapy for weight loss: Gastroplasty, duodenal sleeves, intragastric balloons, and aspiration.

    Kumar, Nitin

  2. Mechanism of Transcriptional Bursting in Bacteria

    Chong, Shasha; Xie, Xiaoliang Sunney

  3. Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

    Zhao, Ziqing; Xie, Xiaoliang Sunney; Roy, Rahul; Gebhardt, J. Christof M.; Suter, David M.; Chapman, Alec R.
    Superresolution microscopy based on single-molecule centroid determination has been widely applied to cellular imaging in recent years. However, quantitative imaging of the mammalian nucleus has been challenging due to the lack of 3D optical sectioning methods for normal-sized cells, as well as the inability to accurately count the absolute copy numbers of biomolecules in highly dense structures. Here we report a reflected light-sheet superresolution microscopy method capable of imaging inside the mammalian nucleus with superior signal-to-background ratio as well as molecular counting with single-copy accuracy. Using reflected light-sheet superresolution microscopy, we probed the spatial organization of transcription by RNA polymerase...

  4. Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering

    Fu, Dan; Xie, Xiaoliang Sunney

  5. Reliable Cell Segmentation Based on Spectral Phasor Analysis of Hyperspectral Stimulated Raman Scattering Imaging Data

    Fu, Dan

  6. A 32-year Perspective on the Origin of Wind Energy in a warming Climate

    Huang, Junling; McElroy, Michael Brendon

  7. Gender, Sexuality, and Cosplay: A Case Study of Male-to-Female Crossplay

    Leng, Rachel Hui Ying
    In recent years, cosplay fans gathering at anime conventions and events all over North America have attracted much public attention and media coverage. These fans, who often refer to themselves as otaku, 1 wear elaborate costumes and makeup to embody various anime, manga, and related video game characters (Cooper-Chen, 2010; Eng, 2012a). The essence of cosplay, or costume-play, involves affective labor where fans transform themselves into chosen anime characters by constructing and wearing costumes, learning signature character poses or dialogue, and masquerading at conventions and events (Okabe, 2012). Crossplay is a subset of cosplay; crossplayers similarly participate in costume-play, except...

  8. Teacher Layoffs in the Worst of Times: A Non-Ideal Theory of Least-Unjust Teacher Firings in L.A. Unified School District

    Theisen-Homer, Victoria Marie; Levinson, Meira L.

  9. Defending “Something Special”: A Portrait of One School’s Response to Instability

    Theisen-Homer, Victoria Marie
    Drawing primarily on interviews with a variety of teachers and other staff at a large urban Title-1 public school in California, Victoria Theisen-Homer paints an ethnographic portrait of how school personnel respond to undesirable changes. Although the school in this study, Skyline High School, had begun to thrive and most of the staff felt their school was “special,” the changes - including increased accountability in preparation for the school’s accreditation audit, turnover and conflicts among school leaders, and crippling budget cuts that removed staff and resources – threatened to compromise the school’s nascent success. While most of the participants in...

  10. Chasing Personal Meaning: Pedagogical Lessons through Always Running

    Theisen-Homer, Victoria Marie
    In this autobiographical narrative, the author recounts her experiences teaching the novel Always Running with her English classes at a high school in a gang heavy area. When she first started teaching, this teacher struggled to engage students. One particularly disruptive student requested to read Always Running, but the teacher initially resisted teaching the text. However, student interest in the novel endured, and the teacher finally decided to take a risk and teach it. She used the novel in both her freshmen “intervention” and junior English classes. Throughout the resulting lessons, the teacher formed meaningful relationships with her students and...

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