TORRUELLA NARANJO, ANDREA MEILYN
El ciclo infectivo viral en una planta huésped susceptible de infección, se inicia en la mayoría de los casos, con la entrada del virus en las células de la epidermis o del mesófilo, a través de las heridas producidas mediante inoculación mecánica o con la ayuda de vectores biológicos (insectos, nemátodos, hongos, etc.). Una vez completado los primeros ciclos de replicación los virus deben ser capaces de traslocarse intracelularmente hasta alcanzar los canales citoplasmáticos que conectan dos células contiguas, denominados plasmodesmos (PDs), los cuales, en circustancias normales solo permiten el paso de pequeñas moléculas e iones entre células (Carrington et...
GARCÍA LÓPEZ, RAFAEL
The present work is based on previous results obtained from the analysis of sRNA populations determined by deep sequencing (Next Generation Sequencing) from melon plants (Cucumis melo L. cv. Piel de Sapo) exposed to different adverse conditions in order to carry out a systematic study of the response to stress, in which a predominant accumulation of sequences of 24 nucleotides was observed, followed by sequences of 21 nucleotides in length (the usual in most of the miRNAs described).
To determine the possible biological activity of these sequences, as well as to identify and describe new melon miRNAs (different to the miRNAs...
MANUKYAN MELKUMYAN, ERIKA
Lately, there has been an exponential advance in the biomedical field. Nonetheless these discoveries do not really mean direct mean direct benefits for the patients, or take a long time to arrive to the population. The following study has analyzed the situation is the technology transfer in Spain, the problems involved, and the available tools to solve this problem.
Spain is a very powerful source of scientific knowledge, with big advances in the biomedical field, but that advances do not arrive to the economy generation, nor to the general population. How should translational medicine be strengthened in Spain? How does knowledge...
FUSTER PONS, ALBERTO
DELLA proteins are transcriptional regulators whose degradation is induced by gibberellins (GAs), plant hormones that participate in the modulation of numerous processes of development and defense against stress. DELLA proteins are not able to bind themselves to DNA and act through the interaction with dozens of transcription factors, modulating their activity, constituting central nodes for the integration of different signaling pathways. The implication of DELLA proteins in so many processes (i) makes it difficult to study each of their functions without affecting others and (ii) reduces the possibilities of their use as a biotechnological tool. It is for this reason...
CALLEJA CABRERA, JULIÁN
DELLA proteins, the master repressors of the gibberellin (GA) signaling pathway, are thought to regulate gene expression by mechanisms other than their interaction with bona fide transcription factors. In particular, current work in our lab shows that DELLA and their atypical interactors prefoldins are able to interact with and regulate a number of proteins that are part of the basal transcriptional machinery, regulating the RNA polymerase II activity. Among the novel interactors being studied are proteins involved in mRNA splicing.
In this TFM, we have investigated the participation of DELLA and prefoldin in alternative splicing by analyzing protein-protein interaction between...
MARTÍN GUINDAL, ANDREA
Self-cleaving ribozymes such as the hammerhead (HHR), the hepatitis-¿ (HDV) or the twister (Tw) motifs, are a group of small catalytic RNAs with a numerous and widespread occurrence in the genomes of organisms from all domains of life. Previous data showed that HHR and HDV ribozymes are frequently found in mobile genetic elements such as retrotransposons, which have efficiently colonized most eukaryotic genomes. In this work, we have characterized two genomic ribozymes from plants, as Tw and HHR, following two different lines of research.
Firstly, our bioinformatic mining of twister ribozymes reveals their conserved occurrence in LINE retrotransposons of the RTE...
MARTÍNEZ CENTELLES, LLUÍS CARLES
In our laboratory we are investigating about the molecular mechanisms by which DELLA proteins
regulate gene expression in plants. DELLA are the negative regulators of the signaling pathway for
gibberellins and their levels are negatively regulated by this hormone. The results obtained in the
laboratory, together with those of others, have shown that an important part of this regulation occurs
through the physical interaction of DELLA proteins with transcription factors, in some cases inactivating
them, while in others the interaction promotes their activity. The latest results of the laboratory suggest
that DELLA can act through other mechanisms to regulate gene expression, in particular, physical
interactions have been...
MINGUILLÓN CAMPOS, SAMUEL
Throughout evolution, plants have been developing defence systems against different abiotic and biotic aggressions by their environment. These defensive systems include both constitutive and inducible defences. In response to stress signals, plants synthesize defence proteins and different chemical compounds. These compounds can carry out direct defensive functions, that is, acting like antioxidants, antibacterial or antifungal. Phenolic compounds and alkaloids, as well as some volatile organic compounds (VOCs) with less polarity and molecular weight, belong to this defensive compounds group.
In this Master¿s degree final project we propose the study of the function of a new monoterpene synthase (MTS1) and a...
OLEAS PALACIOS, LILIANA GRICEL
In this project Weibe & Oyarzún¿s metabolic burden model will be integrated in the dynamic model of synthetic gene circuits. A circuit for control of protein expression, and a incoherent feedforwad one will be used. The parameters of the integrated model will be tuned by a multi-objective optimization design approach taking into account the experimental data from the lab.
PATIÑO SERRATE, JUAN PABLO
Una gran cantidad de edificios se construyen utilizando muros de corte de hormigón armado, para brindar mayor rigidez y resistencia a esfuerzos horizontales producidos por las acciones del sismo y del viento. La gran mayoría de los ingenieros calculistas diseñan estos muros de corte tomando en cuenta exclusivamente la rama elástica-lineal de los materiales, obteniendo así elementos de hormigón que cumplen los requisitos normativos, pero que quizás se encuentran sobredimensionados.
En este trabajo de fin de máster, se comparan las ventajas que se tiene entre realizar un análisis de muros de corte tomando en cuenta solamente su comportamiento elástico-lineal, y de...
ARRANZ MARTÍNEZ, DANIEL
The main aim of this Final Master's Project is to study the export of the agri-food exporting companies of the Valencian Community, in order to make a comparative analysis with the general location of the rest of the companies of the Valencian Community and to determine if there are differences in the localization patterns of both groups of companies.
In the first place, a database of the main Valencian exporting companies, that is, those that export for a value exceeding one million euros, has been prepared based on information collected from the Chamber of Commerce: Directory of Exporting Companies (2010, 2013...
The project consists in the design a brain computer interface based on electroencephalographic (EEG) signals to control the movements and actions voluntarily of an industrial robot. We will work on the acquisition and calibration of the EEG signal, designing the most appropriate interface to move the robot, developing the robot control application and validating the quality of the results obtained through real tests.
As a result, a cross-platform application in C ++ has been obtained, which together with Openvibe is able to control an industrial robot from the Staubbli company based on the Steady State Visually Evoked Potentials (SSVEP) paradigm.
CANO NISTAL, PABLO
El objetivo del trabajo consiste en dotar de robustez a estrategias de control clásicas (tanto para sistemas de control SISO como MIMO) agregando dos filtros en el lazo de control: un filtro en la referencia y otro filtro en la realimentación. Los parámetros de dichos filtros serán sintonizados utilizando algoritmos evolutivos, planteando un problema de minimización del peor caso (min-max). La función de coste será planteada como el tiempo de establecimiento del lazo cerrado sujeto a restricciones de sobreoscilación. El trabajo limita la aplicación a procesos modelados como una función de transferencia de primer orden con retardo donde sus parámetros...
VERA BURGOS, ELSA PATRICIA
The monitoring of noise pollution has become an essential requirement for industrialized and developed countries around the world. The traditional way to measure noise pollution is through the use of professional sound level meters, which are expensive and large-sized. Currently, with the emergence of smart mobile devices that are endowed with multiple sensors, a new paradigm has emerged, called crowdsensing, which takes advantage of the ability to detect mobile crowds, becoming a popular field of research and applications. In this work we propose GRCSensing, an environmental monitoring system based on crowdsensing that is able to measure noise pollution. GRCSensing consists...
SÁNCHEZ GARCÍA, DANIEL
In this project it carried out the implementation and development of a BCI (brain-computer interface) application for communication within a hospital environments is carried out. Specifically, the interface created has been designed for hospital patients with motor disabilities, so that they can be more independent when carrying out some very common household activities such as turning on and off lights or call the doctor and others.
The project carried from out part of my work of end of university degree. In the previous work the connection between the Enobio 8 helmet, in charge of the reading of electroencephalograms (EEG) and LabVIEW,...
SINISTERRA SOLIS, NELSON KEVIN
In this paper, the relationship between the activities developed by universities and the dynamics of innovation of the Spanish autonomous communities is analyzed. It starts from the theory that includes: the theoretical ways that relate the innovation with the development and economic growth, the regional innovation systems theories and the triple helix model like the theoretical element that relates the actions of the universities with the innovation. Next, its make a description of the methodological process applied in the empirical development of the work, doing more importance the application of exploratory spatial data analysis, qualitative comparative analysis and econometric analysis...
ALMEIDA CARRERA, JUAN CARLOS
Development of a embedded system that, based on the electronic data installed in the boat and the complementary data installed in the embedded system (GPS, gyroscope and accelerometers), estimates the correct data of actual navigation, boat speed and current) for be sent to the browser tablet. In the project to obtain the calibration procedures of the instruments, implement algorithms to estimate the measurements and transmission by Bluetooth or other Bluetooth devices
MONTERREY VIÑA, ADRIÁN
This academic work is an analysis of the differentiated policies for family farming in 3 countries corresponding to the 3 main continental regions of Latin America, from Costa Rica for the central region, Peru in the andean region and Brazil in the southern region. The applied methodology consists of the study of all the aspects that make up the policies of family farming, from the definitions, typologies and some basic data of family farming, going through the institutionality and policies, to budget support to specific agricultural programs family in the countries. From the results of the analysis, we can deduce...
WALID GHOBAR, ENIO
"This article might interest you", "People who bought this article, also bought ..." or "This might also interest you" are phrases that are increasingly present in the daily activity of users that consume products and services in virtual stores and other services. The reason for it is that recommendation systems have been consolidated as a strong trend for the growth of digital commerce in recent years, especially with regards to big data. Advances and the cheapening of technologies have allowed many companies to build their virtual environments to complement their physical store, or they were even created in a purely...
SANTOS NAVARRO, FERNANDO NÓBEL
A efectos de maximizar el rendimiento y productividad de los bioprocesos, la biotecnología industrial actual ha de hacer frente a problemas críticos, como son el modelado, la estimación de variables clave, y el diseño de mecanismos de actuación (control) sobre el estado metabólico de los microorganismos. En los últimos años, los turbidostatos de pequeña escala, que usan un circuito de realimentación para mantener constante la densidad celular, están empezando a estar disponibles en los laboratorios para realizar caracterización y escalado de sistemas biológicos sin restricciones de nutrientes. De esta forma, los turbidostatos son una herramienta prometedora para ser utilizada como...