Recursos de colección

Repositório Comum (28.376 recursos)

É um repositório para instituições de ensino e investigação produtoras de literatura científica cuja dimensão ainda não justifica a criação de um repositório próprio. Permite integrar instituições, grupos ou indivíduos na infra-estrutura do projecto, nomeadamente através das pesquisas do Portal RCAAP e da B-On.

Mostrando recursos 1 - 20 de 92

  1. Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?

    Costa, Filipa A.; Scullin, Claire; Al-Taani, Ghaith; Hawwa, Ahmed F.; Anderson, Claire; Bezverhni, Zinaida; Binakaj, Zahida; Cordina, Maria; Foulon, Veerle; Garcia de Bikuña, Borja; Gier, Han de; Granås, Anne Gerd; Grinstova, Olga; Griese-Mammen, Nina; Grincevicius, Jonas; Grinceviciene, Svitrigaile; Kaae, Susanne; Kubiliene, Loreta; Mariño, Eduardo L.; Martins, Silvia; Modamio, Pilar; Nadin, Giancarlo; Nørgaard, Lotte Stig; Obarcanin, Emina; Tadic, Ivana; Tasic, Ljiljana; McElnay, James C.; Hersberger, Kurt E.; Westerlund, Tommy
    Rationale, Aims, and Objectives Pharmaceutical care involves patient-centred pharmacist activity to improve medicines management by patients. The implementation of this service in a comprehensive manner, however, requires considerable organisation and effort, and indeed, it is often not fully implemented in care settings. The main objective was to assess how pharmaceutical care provision within community pharmacy has evolved over time in Europe.

  2. Capture of opiates by ionic liquids

    Restolho, José; Barroso, Mário; Dias, Mário; Afonso, Carlos A. M.; Saramago, Benilde
    The final publication is available at Springer via http://dx.doi.org/10.1007/s10953-014-0272-2

  3. Capture of opiates by ionic liquids

    Restolho, José; Barroso, Mário; Dias, Mário; Afonso, Carlos A. M.; Saramago, Benilde
    The final publication is available at Springer via http://dx.doi.org/10.1007/s10953-014-0272-2

  4. Validation and application of an UPLC–MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market

    Simões, Susana Sadler; Silva, Inês; Castañera Ajenjo, Antonio; Dias, Mário João
    An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids and/or their metabolites in urine samples (1mL). Prior to extraction the samples were subjected to an enzymatic hydrolysis using β-glucuronidase followed by a SPE procedure using Oasis(®) HLB 3cc (60mg) columns. The chromatographic separation was performed with an Acquity UPLC(®) HSS T3 (50mm×2.1mm i.d., 1.8μm) reversed-phase column using a gradient with methanol-ammonium formate 2mM (0.1% formic acid) and with a run time of 9.5min. The method was validated in terms of selectivity, capacity of...

  5. Validation and application of an UPLC–MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market

    Simões, Susana Sadler; Silva, Inês; Castañera Ajenjo, Antonio; Dias, Mário João
    An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids and/or their metabolites in urine samples (1mL). Prior to extraction the samples were subjected to an enzymatic hydrolysis using β-glucuronidase followed by a SPE procedure using Oasis(®) HLB 3cc (60mg) columns. The chromatographic separation was performed with an Acquity UPLC(®) HSS T3 (50mm×2.1mm i.d., 1.8μm) reversed-phase column using a gradient with methanol-ammonium formate 2mM (0.1% formic acid) and with a run time of 9.5min. The method was validated in terms of selectivity, capacity of...

  6. Gamma-hydroxybutyric acid endogenous production and postmortem behaviour - The importance of different biological matrices, cut-off reference values, sample collection and storage conditions

    Castro, André L.; Dias, Mário; Reis, Flávio; Teixeira, Helena M.
    Gamma-Hydroxybutyric Acid (GHB) is an endogenous compound with a story of clinical use, since the 1960's. However, due to its secondary effects, it has become a controlled substance, entering the illicit market for recreational and "dance club scene" use, muscle enhancement purposes and drug-facilitated sexual assaults. Its endogenous context can bring some difficulties when interpreting, in a forensic context, the analytical values achieved in biological samples. This manuscript reviewed several crucial aspects related to GHB forensic toxicology evaluation, such as its post-mortem behaviour in biological samples; endogenous production values, whether in in vivo and in post-mortem samples; sampling and storage...

  7. Gamma-hydroxybutyric acid endogenous production and postmortem behaviour - The importance of different biological matrices, cut-off reference values, sample collection and storage conditions

    Castro, André L.; Dias, Mário; Reis, Flávio; Teixeira, Helena M.
    Gamma-Hydroxybutyric Acid (GHB) is an endogenous compound with a story of clinical use, since the 1960's. However, due to its secondary effects, it has become a controlled substance, entering the illicit market for recreational and "dance club scene" use, muscle enhancement purposes and drug-facilitated sexual assaults. Its endogenous context can bring some difficulties when interpreting, in a forensic context, the analytical values achieved in biological samples. This manuscript reviewed several crucial aspects related to GHB forensic toxicology evaluation, such as its post-mortem behaviour in biological samples; endogenous production values, whether in in vivo and in post-mortem samples; sampling and storage...

  8. Development, optimization, and validation of a novel extraction procedure for the removal of opiates from human hair’s surface

    Restolho, José; Barroso, Mário; Saramago, Benilde; Dias, Mário; Afonso, Carlos A. M.
    This is the accepted version of the following article: Drug Test. Analysis, 7, 385–392. doi: 10.1002/dta.1695, which has been published in final form at http://dx.doi.org/10.1002/dta.1695 . This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy: http://olabout.wiley.com/WileyCDA/Section/id-828039.html

  9. Development, optimization, and validation of a novel extraction procedure for the removal of opiates from human hair’s surface

    Restolho, José; Barroso, Mário; Saramago, Benilde; Dias, Mário; Afonso, Carlos A. M.
    This is the accepted version of the following article: Drug Test. Analysis, 7, 385–392. doi: 10.1002/dta.1695, which has been published in final form at http://dx.doi.org/10.1002/dta.1695 . This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy: http://olabout.wiley.com/WileyCDA/Section/id-828039.html

  10. Comparative measurement and quantitative risk assessment of alcohol consumption through wastewater-based epidemiology: an international study in 20 cities

    Ryu, Yeonsuk; Barceló, Damià; Barrone, Leon P.; Bijlsma, Lubertus; Castiglioni, Sara; Voogt, Pimde; Emke, Erik; Hernández, Félix; Lai, Foon Yin; Lopes, Álvaro; López de Alda, Miren; Mastroianni, Nicola; Munro, Kelly; O'Brien, Jake; Ort, Christoph; Plósz, Benedek G.; Reid, Malcolm J.; Yargeau, Viviane; Thomas, Kevin V.
    This work is licensed under a CC-BY licence - https://creativecommons.org/licenses/by/4.0/

  11. Comparative measurement and quantitative risk assessment of alcohol consumption through wastewater-based epidemiology: an international study in 20 cities

    Ryu, Yeonsuk; Barceló, Damià; Barrone, Leon P.; Bijlsma, Lubertus; Castiglioni, Sara; Voogt, Pimde; Emke, Erik; Hernández, Félix; Lai, Foon Yin; Lopes, Álvaro; López de Alda, Miren; Mastroianni, Nicola; Munro, Kelly; O'Brien, Jake; Ort, Christoph; Plósz, Benedek G.; Reid, Malcolm J.; Yargeau, Viviane; Thomas, Kevin V.
    This work is licensed under a CC-BY licence - https://creativecommons.org/licenses/by/4.0/

  12. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

    NCD Risk Factor Collaboration
    Background: Underweight and severe and morbid obesity are associated with highly elevated risks of adverse health outcomes. We estimated trends in mean body-mass index (BMI), which characterises its population distribution, and in the prevalences of a complete set of BMI categories for adults in all countries.

  13. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

    NCD Risk Factor Collaboration
    Background: Underweight and severe and morbid obesity are associated with highly elevated risks of adverse health outcomes. We estimated trends in mean body-mass index (BMI), which characterises its population distribution, and in the prevalences of a complete set of BMI categories for adults in all countries.

  14. INDIVIDUO: Results from a patient-centered lifestyle intervention for obesity surgery candidates

    Camolas, José; Santos, Osvaldo; Moreira, Pedro; Carmo, Isabel do
    This manuscript is made available under a CC-BY-NC-ND 4.0 license - https://creativecommons.org/licenses/by-nc-nd/4.0/

  15. INDIVIDUO: Results from a patient-centered lifestyle intervention for obesity surgery candidates

    Camolas, José; Santos, Osvaldo; Moreira, Pedro; Carmo, Isabel do
    This manuscript is made available under a CC-BY-NC-ND 4.0 license - https://creativecommons.org/licenses/by-nc-nd/4.0/

  16. A century of trends in adult human height

    NCD Risk Factor Collaboration
    Sob uma licença CC-BY - http://creativecommons.org/licenses/by/4.0/

  17. A century of trends in adult human height

    NCD Risk Factor Collaboration
    Sob uma licença CC-BY - http://creativecommons.org/licenses/by/4.0/

  18. DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: the role of base excision repair genes polymorphisms

    Azevedo, Ana P.; Silva, Susana N.; Lima, João P. de; Reichert, Alice; Lima, Fernando; Júnior, Esmeraldina; Rueff, José
    Sob uma licença CC-BY-NC-ND - http://creativecommons.org/licenses/by-nc-nd/4.0/

  19. DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: the role of base excision repair genes polymorphisms

    Azevedo, Ana P.; Silva, Susana N.; Lima, João P. de; Reichert, Alice; Lima, Fernando; Júnior, Esmeraldina; Rueff, José
    Sob uma licença CC-BY-NC-ND - http://creativecommons.org/licenses/by-nc-nd/4.0/

  20. Exames de diagnóstico não-invasivos: a ansiedade percepcionada pelo paciente

    Neves, Ana Cristina
    O presente artigo analisa em que medida a informação prestada aos utentes antes da realização de exames de diagnóstico não-invasivos, contribui para a redução da ansiedade percepcionada pelo sujeito. A amostra do estudo constituída por 50 utentes de um hospital da área de Lisboa e Vale do Tejo, de ambos os sexos com idades compreendidas entre os 20 e 70 anos, foi dividida em dois grupos; i) Experimental (informados) e ii) Controlo (não informados). Recorremos à adaptação portuguesa do State Trait Anxiety Inventory (STAI) como instrumento de medida e foram originalmente construídos cinco Folhetos Informativos, contendo informação específica sobre os exames...

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