Recursos de colección

E-Prints Complutense (95.115 recursos)

En este archivo los docentes e investigadores de la UCM depositan sus documentos en acceso abierto (open access)

Estado = En prensa

Mostrando recursos 1 - 20 de 187

  1. Non-Lipschitz differentiable functions on slit domains

    Bernal-González, L.; Jimenez Rodriguez, G. A.; Muñoz-Fernández, Gustavo A.; Seoane-Sepúlveda, Juan B.
    It is proved the existence of large algebraic structures—including large vector subspaces or infinitely generated free algebras—inside the family of non-Lipschitz differentiable real functions with bounded gradient defined on special non-convex plane domains. In particular, this yields that there are many differentiable functions on plane domains that do not satisfy the mean value theorem.

  2. Bifurcations and Attractor-Repeller Splittings of Non-Saddle Sets

    Barge, Héctor; Rodríguez Sanjurjo, José Manuel
    This paper is devoted to the study of some aspects of the stability theory of flows. In particular, we study Morse decompositions induced by non-saddle sets, including their corresponding Morse equations, attractor-repeller splittings of non-saddle sets and bifurcations originated by implosions of the basin of attraction of asymptotically stable fixed points. We also characterize the non-saddle sets of the plane in terms of the Euler characteristic of their region of influence.

  3. Los intermediarios fiscales y su impacto en la concienciación cívico-tributaria: gestión y recaudación tributaria

    Bonell Colmenero, Ramón
    El problema creciente de falta de recaudación suficiente ante el endeudamiento de las Administraciones Públicas, es el reflejo de una defectuosa concepción del modelo de desarrollo y también del procedimiento de gestión y recaudación tributaria llevados a cabo. Es por ello que en el presente trabajo ofrecemos la solución idónea.

  4. Análisis de discursos y epistemología de las mediaciones en las prácticas sociales de la comunicación. Propuesta metodológica de un modelo

    Piñuel Raigada, José Luis; Gaitán Moya, Juan Antonio; Lozano Ascencio, Carlos
    A partir de una propuesta para la definición de DISCURSO y sus clases, se aborda la revisión epistemológica de las teorías del conocimiento y de las teorías sociales de las cuales derivan los diversos modelos que han sido formulados en Teoría de la Comunicación cuando se aspira a describir, explicar, evaluar y/o intervenir en las prácticas sociales de comunicación. Este objetivo implica el diseño de modelos capaces de tomar en cuenta las mediaciones que la comunicación experimenta y produce respecto al dominio de las interacciones sociales y de las condiciones existenciales de las conductas. En consecuencia se expone un modelo...

  5. On SIR epidemic models with generally distributed infectious periods: Number of secondary cases and probability of infection

    Gómez-Corral, Antonio; López García, M.
    Recently, Clancy [SIR epidemic models with general infectious period distribution, Statist. Prob. Lett. 85 (2014) 1–5] has shown how SIR epidemics in which individuals’ infection periods are not necessarily exponentially distributed may be modeled in terms of a piecewise-deterministic Markov process (PDMP). In this paper, we present a more detailed description of the underlying PDMP, from which we analyze the population transmission number and the infection probability of a certain susceptible individual.

  6. The Heat Equaton with General Periodic Boundary Conditions

    Rodríguez Bernal, Aníbal
    In this paper we address the well posedness of the linear heat equation under general periodic boundary conditions in several settings depending on the properties of the initial data. We develop an Lq theory not based on separation of variables and use techniques based on uniform spaces. We also allow less directions of periodicity than the dimension of the problem. We obtain smoothing estimates on the solutions. Also, based on symmetry arguments, we handle Dirichlet or Neumann boundary conditions in some faces of the unit cell.

  7. Retrial queues and related models

    Gómez-Corral, Antonio; Phung-Duc, Tuan

  8. Recent applications on the combination of Mesoporous Silica Nanoparticles with Nucleic Acids: Development of Bioresponsive Devices, Carriers and Sensors

    Castillo Romero, Rafael; Baeza, Alejandro; Vallet Regí, María
    The discovery and control of the biological roles mediated by nucleic acids have turned them into a powerful tool for the development of advanced biotechnological materials. Much is the importance of those gene-keeping biomacromolecules that even nanomaterials have succumbed to the claimed benefits of DNA and RNA. Currently, there could be found in the literature a practically intractable number of examples which report the use in combination of nanoparticles with nucleic acids, which demands boundedness. Following this premise, this revision will only cover the most recent and powerful strategies developed to exploit the possibilities of nucleic acids as biotechnological materials...

  9. Recent applications on the combination of Mesoporous Silica Nanoparticles with Nucleic Acids: Development of Bioresponsive Devices, Carriers and Sensors

    Castillo Romero, Rafael; Baeza, Alejandro; Vallet Regí, María
    The discovery and control of the biological roles mediated by nucleic acids have turned them into a powerful tool for the development of advanced biotechnological materials. Much is the importance of those gene-keeping biomacromolecules that even nanomaterials have succumbed to the claimed benefits of DNA and RNA. Currently, there could be found in the literature a practically intractable number of examples which report the use in combination of nanoparticles with nucleic acids, which demands boundedness. Following this premise, this revision will only cover the most recent and powerful strategies developed to exploit the possibilities of nucleic acids as biotechnological materials...

  10. Self-Immolative Polymers as novel pH-responsive gate keepers for drug delivery

    Gisbert Garzarán, Miguel; Lozano Borregón, Daniel; Vallet Regí, María; Manzano García, Miguel
    A novel pH-sensitive nanocarrier based on mesoporous silica nanoparticles with self-immolative polymers blocking the pore openings is presented. Triggered release by acid pH is demonstrated, together with their in vitro biocompatibility and effective cell internalisation, which makes this new material a promising candidate for future applications in cancer treatment.

  11. Self-Immolative Polymers as novel pH-responsive gate keepers for drug delivery

    Gisbert Garzarán, Miguel; Lozano Borregón, Daniel; Vallet Regí, María; Manzano García, Miguel
    A novel pH-sensitive nanocarrier based on mesoporous silica nanoparticles with self-immolative polymers blocking the pore openings is presented. Triggered release by acid pH is demonstrated, together with their in vitro biocompatibility and effective cell internalisation, which makes this new material a promising candidate for future applications in cancer treatment.

  12. 3D scaffold with effective multidrug sequential release against bacteria biofilm

    García-Álvarez, Rafaela; Izquierdo-Barba, Isabel; Vallet Regí, María
    Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved with the design of 3D implants, which combine the merits of osseous regeneration and local multidrug therapy so as to avoid bacterial growth, drug resistance and the feared side effects. Herein, hierarchical 3D multidrug scaffolds based on nanocomposite bioceramic and polyvinyl alcohol (PVA) prepared by rapid prototyping with an external coating of gelatin-glutaraldehyde (Gel-Glu) have been fabricated. These 3D scaffolds contain three antimicrobial agents (rifampin, levofloxacin and vancomycin), which have been...

  13. 3D scaffold with effective multidrug sequential release against bacteria biofilm

    García-Álvarez, Rafaela; Izquierdo-Barba, Isabel; Vallet Regí, María
    Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved with the design of 3D implants, which combine the merits of osseous regeneration and local multidrug therapy so as to avoid bacterial growth, drug resistance and the feared side effects. Herein, hierarchical 3D multidrug scaffolds based on nanocomposite bioceramic and polyvinyl alcohol (PVA) prepared by rapid prototyping with an external coating of gelatin-glutaraldehyde (Gel-Glu) have been fabricated. These 3D scaffolds contain three antimicrobial agents (rifampin, levofloxacin and vancomycin), which have been...

  14. Molecular gates in mesoporous bioactive glasses for the treatment of bone tumors and infection

    Polo, Lorena; Gomez Cerezo, Natividad; Vivancos, Jose Luis; Sancenón, Félix; Arcos, Daniel; Vallet Regí, María; Martínez Máñez, Ramón
    Silica mesoporous nanomaterials have been proved to have meaningful application in biotechnology and biomedicine. Particularly, mesoporous bioactive glasses are recently gaining importance thanks to their bone regenerative properties. Moreover, the mesoporous nature of these materials makes them suitable for drug delivery applications, opening new lines in the field of bone therapies. In this work, we have developed innovative nanodevices based on the implementation of adenosine triphosphate (ATP) and e-poly-l-lysine molecular gates using a mesoporous bioglass as an inorganic support. The systems have been previously proved to work properly with a fluorescence probe and subsequently with an antibiotic(levofloxacin) and an antitumoral...

  15. Riesgos psicosociales en una Universidad de Ecuador: mediante técnicas de Lógica Difusa

    Gómez Gómez, Francisco; López Cano, Ana; Munuera Gómez, Pilar
    Se valoran los riesgos psicosociales de los trabajadores y trabajadoras, docentes y no docentes, de la Universidad Técnica de Cotopaxi, ubicada en Latacunga, Ecuador, a través de un cuestionario de evaluación de factores psicosociales, validado por el Instituto Navarro de Salud Laboral de la Comunidad Autónoma de Navarra. Mediante Técnicas de Lógica Difusa, aplicadas en la interpretación de los datos del cuestionario, se consigue un avance en dar una respuesta grupal de los encuestados y las encuestadas, apoyada en la medición de la in certidumbre y la pertenencia al grupo. También se usaron Técnicas de Lógica Tradicional, con el fin...

  16. Los agentes informativos en los telediarios: reforzamiento del statu quo y cambio sociopolítico. El análisis del OCITV

    Aparicio González, Daniel; Salgado, Santamaría; Díaz, Arias
    En este trabajo se presentan los resultados del Observatorio de la Calidad de los Informativos de Televisión relativos a la presencia de los agentes informativos en los telediarios de 5 cadenas de ámbito estatal. Desarrollado entre el otoño de 2013 y la primavera de 2015, se analizan 258 programas atendiendo a las variables de fuentes, quién habla (frecuencia de categorías y personas) y de quién se habla (frecuencia de menciones de categorías y personas y valoración de categorías). Los resultados muestran unos informativos fundamentados en declaraciones, con un predominio de los agentes institucionales (especialmente el Gobierno, su presidente y su...

  17. Assessment of the sensitivity and specificity of serological (IFAT) and molecular (direct PCR) techniques for diagnosis of leishmaniasis in lagomorphs using a Bayesian approach

    Cruz Conty, María Luisa de la; Pérez, Andres; Domínguez, Mercedes; Moreno, Inmaculada; García Benzaquén, Nerea; Martínez Alares, Irene; Navarro Gómez, Alejandro; Domínguez Rodríguez, Lucas; Álvarez, Julio
    Leishmaniasis, caused by Leishmania infantum, is a vector-borne zoonotic disease that is endemic to the Mediterranean basin. The potential of rabbits and hares to serve as competent reservoirs for the disease has recently been demonstrated, although assessment of the importance of their role on disease dynamics is hampered by the absence of quantitative knowledge on the accuracy of diagnostic techniques in these species. A Bayesian latent-class model was used here to estimate the sensitivity and specificity of the Immuno-fluorescence antibody test (IFAT) in serum and a Leishmania-nested PCR (Ln-PCR) in skin for samples collected from 217 rabbits and 70 hares...

  18. Disruptive Ambient Music: Mobile Phone Music Listening as Portable Urbanism

    Lasen Díez, Amparo
    This article explores the use of mobile phones as portable remediated sound devices for mobile listening — from boom boxes to personal stereos and mp3 players. This mode of engaging the city through music playing and listening reveals a particular urban strategy and acoustic urban politics. It increases the sonic presence of mobile owners and plays a role in territorialisation dynamics, as well as in eliciting territorial controversies in public. These digital practices play a key role in the enactment of the urban mood and ambience, as well as in the modulation of people’s presence — producing forms of what...

  19. Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer

    Arriola Villalobos, Pedro; Almendral Gómez, Jaime; Garzón Jiménez, Nuria; Ruiz-Medrano, Jorge; Fernández Pérez, Carlos; Martinez de la Casa, Jose Maria; Díaz Valle, David
    Purpose: to determine whether pupil dilation affects biometric measurements and intraocular lens (IOL) power calculation made using the new swept-source optical coherence tomography-based optical biometer (IOLMaster 700©; Carl Zeiss Meditec, Jena, Germany). Procedures: eighty-one eyes of 81 patients evaluated for cataract surgery were prospectively examined using the IOLMaster 700© before and after pupil dilation with tropicamide 1%. The measurements made were: axial length (AL), central corneal thickness (CCT), aqueous chamber depth (ACD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW) and pupil diameter (PD). Holladay II and SRK/T formulas were used to calculate IOL power. Agreement between measurement modes (with...

  20. Maculopatía por puntero láser. ¿Un nuevo problema de salud pública?

    Alda, Javier; Gómez Sanz, Fernando J.; González Martín-Moro, Julio

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.