Recursos de colección

E-Prints Complutense (100.312 recursos)

En este archivo los docentes e investigadores de la UCM depositan sus documentos en acceso abierto (open access)

Estado = En prensa

Mostrando recursos 1 - 19 de 19

  1. Short-term Effects of Overnight Orthokeratology on Corneal Sub-basal Nerve Plexus Morphology and Corneal Sensitivity

    Nombela Palomo, María; Felipe Márquez, Gema; Hernández Verdejo, José Luis; Nieto Bona, Amelia
    Objective: To assess the effects of a short period of orthokeratology (OK) on corneal subbasal nerve plexus (SBNP) morphology and corneal sensitivity. Methods: Measurements were made in 56 right eyes of 56 subjects with low-to-moderate myopia who wore 2 OK lens designs (Group CRT: HDS 100 Paragon CRT, n=35; Group SF: Seefree; n=21) for a period of 1 month and in 15 right eyes of noncontact lens wearers as controls. The variables determined in each participant were corneal sensitivity using a Cochet-Bonnet esthesiometer and 12 SBNP variables determined on laser scanning confocal microscopy images using 3 different software packages. Correlation between...

  2. Short-term Effects of Overnight Orthokeratology on Corneal Sub-basal Nerve Plexus Morphology and Corneal Sensitivity

    Nombela Palomo, María; Felipe Márquez, Gema; Hernández Verdejo, José Luis; Nieto Bona, Amelia
    Objective: To assess the effects of a short period of orthokeratology (OK) on corneal subbasal nerve plexus (SBNP) morphology and corneal sensitivity. Methods: Measurements were made in 56 right eyes of 56 subjects with low-to-moderate myopia who wore 2 OK lens designs (Group CRT: HDS 100 Paragon CRT, n=35; Group SF: Seefree; n=21) for a period of 1 month and in 15 right eyes of noncontact lens wearers as controls. The variables determined in each participant were corneal sensitivity using a Cochet-Bonnet esthesiometer and 12 SBNP variables determined on laser scanning confocal microscopy images using 3 different software packages. Correlation between...

  3. El ensayo audiovisual como metodología de la crisis. Visitando Mercado de futuros (Mercedes Álvarez, 2010)

    Arquero Blanco, Isabel; Deltell Escolar, Luis
    Nuestro trabajo aborda el tema del ensayo audiovisual, es decir, una reflexión del yo con imágenes y sonidos en movimiento y, a veces, con palabras. Para ello queremos indagar en el funcionamiento primero de la idea de ensayo literario desde sus orígenes en Michel de Montaigne, pero también en lo que han dicho sobre esta forma o género otros teóricos. Después mostraremos cómo esta forma de escritura, de pensamiento y, en suma, esta metodología de investigación abierta y creativa, se ha traspasado al documental cinematográfico y audiovisual y ha devenido en un modelo de construcción. Por último, analizaremos Mercado de...

  4. La formación práctica: innovación y minería de datos en el Grado de Trabajo Social

    Munuera Gómez, Pilar; Gómez Gómez, Francisco
    En este capítulo, se presenta la utilidad de las Nuevas Tecnologías de la Información y la Comunicación Social (NTIC) y la minería de datos (o Data Mining), concebidas como un proceso de descubrimiento de nuevas y significativas relaciones, patrones y tendencias al examinar cantidades de datos. Estos temas serán abordados brevemente en su relación y apoyo de las prácticas profesionales del Trabajo Social, de cara a concluir con algunas evidencias que ayuden en el abordaje de los nuevos retos y problemas sociales que se plantean en la actualidad en los diferentes sistemas que configuran el Estado de bienestar social (Gómez...

  5. Charles Bonnet syndrome in a child with congenital glaucoma

    Santos Bueso, Enrique; Serrador García, Mercedes; Sáenz Francés, Federico; Méndez Hernández, Carmen D; Morales Fernández, Laura; Martínez de la Casa, Jose Maria; García Feijoo, Julián; Porta Etessam, Jesús
    Case report: The case is presented of a 12 year-old boy with congenital glaucoma and low visual acuity diagnosed with Charles Bonnet syndrome. This consisted of the acute onset of complex, repetitive, persistent, and with visual hallucinations (people, brooms and coffeemakers) of self-limited evolution without treatment. The patient was diagnosed with congenital glaucoma at 3 years of age, and subjected to a trabeculectomy in right eye, and trabeculectomy and keratoplasty in his left eye. Discussion: Charles Bonnet syndrome symptoms have been described in adults, but their presence in children is poorly reflected in literature, with unknown characteristics and prevalence.

  6. On the arithmetic 4-orbifolds associated to integral quaternary quadratic forms of index 2

    Montesinos Amilibia, José María
    Groups acting properly and discontinuously on the Cartesian product (Formula presented.) of two hyperbolic planes are termed hyperabelian by Picard. The automorphism group (Formula presented.) of a quaternary integral quadratic form f of index 2 is an example of a hyperabelian group. Hence the quotient orbifold (Formula presented.) of the action of (Formula presented.) on (Formula presented.) is a 4-dimensional arithmetic orbifold, endowed with a natural (Formula presented.)-geometry. Plücker coordinates are used to understand (Formula presented.). A real automorphism U of (Formula presented.) induces a real automorphism (Formula presented.) of (Formula presented.) in such a way that if (Formula presented.)...

  7. The role and therapeutic potential of melatonin in age-related ocular diseases

    Crooke, Almudena; Huete Toral, Fernando; Colligris, Basilio; Pintor, Jesús
    The eye is continuously exposed to solar UV radiation and pollutants, making it prone to oxidative attacks. In fact, oxidative damage is a major cause of age-related ocular diseases including cataract, glaucoma, age-related macular degeneration and diabetic retinopathy. Since the nature of lens cells, trabecular meshwork cells, retinal ganglion cells, retinal pigment epithelial cells and photoreceptors is post-mitotic, autophagy plays a critical role in their cellular homeostasis. In age-related ocular diseases, this process is impaired, thus, oxidative damage becomes irreversible. Other conditions such as low- grade chronic inflammation and angiogenesis also contribute to the development of retinal diseases (glaucoma, age-related...

  8. Ciliochoroidal detachment following pure sulfur hexafluoride injection in Descemet stripping automated endothelial keratoplasty

    Gegúndez Fernández, José Antonio; Fernández Vigo, José Ignacio; Díaz Valle, David; Cuiña Sardiña, Ricardo; Benítez del Castillo, José Manuel

  9. Tear Film Osmolarity in Response to Long-Term Orthokeratology Treatment

    Nieto Bona, Amelia; Nombela Palomo, María; Felipe Márquez, Gema; Teus Guezala, Miguel Ángel
    Purpose: To compare tear film osmolarity (TFO) measurements in non-contact lens (CL) wearers and wearers of hydrogel or overnight orthokeratology (OK) CLs, and to assess possible effects of long-term OK on TFO. Methods: Overall, 108 subjects with moderate myopia participated in 2 experiments, and TFO was measured using the TearLab osmolarity system. In experiment 1, TFO measurements were made in 77 right eyes of 23 non-CL wearers, 26 hydrogel wearers, and 28 OK wearers. Subjects in the last 2 groups had worn their CL for at least 3 years. In experiment 2, 31 individuals (habitual soft CL wearers) were enrolled for...

  10. Proton Environments in Biomimetic Calcium Phosphates Formed from Mesoporous Bioactive CaO-SiO2- P2O5 Glasses in vitro: Insights from Solid-State NMR

    Mathew, Renny; Turdean-Ionescu, Claudia; Yu, Yang; Stevensson, Baltzar; Izquierdo-Barba, Isabel; García Fontecha, Ana; Arcos Navarrete, Daniel; Vallet Regí, María; Eden, Mattias
    When exposed to body fluids, mesoporous bioactive glasses (MBGs) of the CaO{SiO2{P2O5 system develop a bone-bonding surface layer that initially consists of amorphous calcium phosphate(ACP), which transforms into hydroxy-carbonate apatite (HCA) with a very similar composition as bone/dentin mineral. Information from various 1H-based solid-state nuclear magnetic resonance (NMR) experiments were combined to elucidate the evolution of the proton speciations both at the MBG surface and within each ACP/HCA constituent of the biomimetic phosphate layer formed when each of three MBGs with distinct Ca, Si, and P contents was immersed in a simulated body fluid (SBF) for variable periods between 15...

  11. Corneal densitometry after photorefractive keratectomy, laser- assisted in situ keratomileusis, and small-incision lenticule extraction

    Poyales Galán, Francisco; Garzón Jiménez, Nuria; Mendicute, Javier; Illarramendi, Igor; Caro, Pedro; Jáñez, Oscar; Argüeso Díaz-Trechuelo, Francisco; López, Alfredo
    Purpose: The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE). Patients and methods: Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants...

  12. Direct Production of Cellulose Nanocrystals from Old Newspapers and Recycled Newsprints

    Campano, Cristina; Miranda, Rubén; Merayo, Noemí; Negro, Carlos; Blanco, Ángeles
    Cellulose nanocrystals (CNC) are high added value products which can be used in many applications. In this research, CNC were directly produced from two recycled papers: old newspapers (ONP) and 100% recycled newsprint (NP). CNC were also obtained from NP by previously isolating the cellulose particles by alkali and bleaching treatments. CNC yield and quality was assessed through lignin and ash determination, X-ray diffraction analysis, atomic force microscopy and thermogravimetric analysis. Not only crystallinities resulted similar (92-95%), but also aspect ratios (L/d) (each in the range of 50-120). However, different CNC purities and hydrolysis and process yields were obtained. Thus,...

  13. Tear cytokine profile of glaucoma patients treated with preservative-free or preserved latanoprost

    Martínez de la Casa, Jose Maria; Pérez Bartolomé, Francisco; Urcelay, Elena; Santiago, José Luis; Moreno Montañes, Javier; Arriola Villalobos, Pedro; Benítez del Castillo, José Manuel; García Feijoo, Julián
    Purpose: To determine variations in cytokine levels of glaucoma patients treated either with preservative-free latanoprost or preserved latanoprost, relative to healthy individuals. Methods: Tear samples were collected from 39 healthy subjects, 20 glaucoma patients treated with preserved latanoprost, and 20 patients treated with preservative-free latanoprost. A set of 27 inflammatory cytokines was analyzed in each group, including interleukin (IL)-1β, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony stimulating factor (G-CSF), granulocyte monocyte colony stimulating factor (GM-CSF), interferon (IFN)-γ, interferon gamma-induced protein (IP)-10, monocyte chemo attractant protein...

  14. Management of Cancer in the Older Age Person: An Approach to ComplexMedical Decisions

    Vallet Regí, María; Manzano García, Miguel; Rodríguez Manas, L.; Checa López, Marta; Aapro, Matti; Balducci, Lodovico
    The management of cancer in older aged people is becoming a common problem due to the aging of the population. There are many variables determining the complex situation that are interconnected. Some of them can be assessed, such as risk of mortality and risk of treatment complications, but many others are still unknown, such as the course of disease, the host-related factors that influence cancer aggressiveness, and the phenotype heralding risk of permanent treatment-related damage. This article presents a dynamic and personalized approach to older people with cancer based on our experience on aging, cancer, and their biological interactions. Also, novel treatments...

  15. Tuning mesoporous silica dissolution in physiological environments: a review

    Paris, J.L.; Colilla, Montserrat; Izquierdo-Barba, Isabel; Manzano García, Miguel; Vallet Regí, María
    Matrix degradation has a major impact on the release kinetics of drug delivery systems. Regarding ordered mesoporous silica materials for biomedical applications, their dissolution is an important parameter that should be taken into consideration. In this paper, we review the main factors that govern the mesoporous silica dissolution in physiological environments. We also provide the necessary knowledge to researchers in the area for tuning the dissolution rate of those matrices, so the degradation could be controlled and the material behaviour optimised.

  16. Los intermediarios fiscales y su impacto en la concienciación cívico-tributaria: gestión y recaudación tributaria

    Bonell Colmenero, Ramón
    El problema creciente de falta de recaudación suficiente ante el endeudamiento de las Administraciones Públicas, es el reflejo de una defectuosa concepción del modelo de desarrollo y también del procedimiento de gestión y recaudación tributaria llevados a cabo. Es por ello que en el presente trabajo ofrecemos la solución idónea.

  17. The Heat Equaton with General Periodic Boundary Conditions

    Rodríguez Bernal, Aníbal
    In this paper we address the well posedness of the linear heat equation under general periodic boundary conditions in several settings depending on the properties of the initial data. We develop an Lq theory not based on separation of variables and use techniques based on uniform spaces. We also allow less directions of periodicity than the dimension of the problem. We obtain smoothing estimates on the solutions. Also, based on symmetry arguments, we handle Dirichlet or Neumann boundary conditions in some faces of the unit cell.

  18. Synergistic action of actinoporin isoforms from the same sea anemone species assembled into functionally active heteropores

    Rivera de Torre, Esperanza; García Linares, Sara; Alegre Cebollada, Jorge; Lacadena, Javier; Gavilanes, José G.; Martínez del Pozo, Álvaro
    Among the toxic polypeptides secreted in the venom of sea anemones, actinoporins are pore forming toxins whose toxic activity relies on the formation of oligomeric pores within biological membranes. Intriguingly, actinoporins appear as multigene families which give rise to many protein isoforms in the same individual displaying high sequence identities but large functional differences. However, the evolutionary advantage of producing such similar isotoxins is not fully understood. Here, using sticholysins I and II (StnI and StnII) from the sea anemone Stichodactyla helianthus, it is shown that actinoporin isoforms can potentiate each other’s activity. Through hemolysis and calcein releasing assays, it...

  19. Costs for conventional and renewable fuels and electricity in the worldwide transport sector: a mean-variance portfolio approach

    Guerrero-Lemus, Ricardo; Marrero, Gustavo A.; Puch, Luis A.
    In this paper we analyze the role of changes in the fuel mix on emissions reduction and the diversification of risks associated to rising prices of energy. To this purpose we evaluate the average cost and the cost volatility of alternative fuel combinations in the road transport sector by means of the Mean-Variance Portfolio Theory. The results suggest big gains in diversification of risks and emissions reduction associated with shifts away the current fuel mix, which is more than 90% concentrated worldwide in fossil fuels. Those shifts are discussed vis à vis the policy recommendations of the International Energy Agency on fuel...

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