Recursos de colección

ARCA - Access to Research and Communication Annals - IGC Repository (1.013 recursos)

The Institutional Repository of Instituto Gulbenkian de Ciência, developed under the project RCAAP, is intended to collect, preserve and promote open access to the intellectual production of their researchers.

Eco-evolutionary genetics

Mostrando recursos 1 - 6 de 6

  1. An experimental test on the probability of extinction of new genetic variants

    Chelo, Ivo M.; Nédli, Judit; Gordo, Isabel; Teotónio, Henrique
    In 1927, J.B.S. Haldane reasoned that the probability of fixation of new beneficial alleles is twice their fitness effect. This result, later generalized by M. Kimura, has since become the cornerstone of modern population genetics. There is no experimental test of Haldane's insight that new beneficial alleles are lost with high probability. Here we demonstrate that extinction rates decrease with increasing initial numbers of beneficial alleles, as expected, by performing invasion experiments with inbred lines of the nematode Caenorhabditis elegans. We further show that the extinction rates of deleterious alleles are higher than those of beneficial alleles, also as expected....

  2. Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel

    Noble, Luke M; Chelo, Ivo; Guzella, Thiago; Afonso, Bruno; Riccardi, David D; Ammerman, Patrick; Dayarian, Adel; Carvalho, Sara; Crist, Anna; Pino-Querido, Ania; Shraiman, Boris; Rockman, Matthew V; Teotónio, Henrique
    The deposited article is a pre-print version and it has not been submitted to peer reviewing. This article version was provided by bioRxiv and is the preprint first posted online Mar. 26, 2017. This publication hasn't any creative commons license associated. The deposited article version contains attached the supplementary materials within the pdf.

  3. Experimental determination of invasive fitness in Caenorhabditis elegans

    Chelo, Ivo M
    The deposited article is a post-print version and has been submitted to peer reviewing. This publication hasn't any creative commons license associated. The deposited article version contains attached some supplementary materials within the pdf. Some supplementary materials are not present in the uploaded version of the article, are present in the publisher's page in the following link: https://www.nature.com/articles/nprot.2014.098#integrated-supplementary-information

  4. Experimental determination of invasive fitness in Caenorhabditis elegans

    Chelo, Ivo M
    The deposited article is a post-print version and has been submitted to peer reviewing. This publication hasn't any creative commons license associated. The deposited article version contains attached some supplementary materials within the pdf. Some supplementary materials are not present in the uploaded version of the article, are present in the publisher's page in the following link: https://www.nature.com/articles/nprot.2014.098#integrated-supplementary-information

  5. The role of hermaphrodites in the experimental evolution of increased outcrossing rates in Caenorhabditis elegans

    Carvalho, Sara; Chelo, Ivo M; Goy, Christine; Teotónio, Henrique
    This deposit is composed by the main article plus the supplementary materials of the publication.

  6. Evolution of Outcrossing in Experimental Populations of Caenorhabditis elegans

    Teotonio, Henrique; Carvalho, Sara; Manoel, Diogo; Roque, Miguel; Chelo, Ivo M.
    Caenorhabditis elegans can reproduce exclusively by self-fertilization. Yet, males can be maintained in laboratory populations, a phenomenon that continues to puzzle biologists. In this study we evaluated the role of males in facilitating adaptation to novel environments. For this, we contrasted the evolution of a fitness component exclusive to outcrossing in experimental populations of different mating systems. We introgressed a modifier of outcrossing into a hybrid population derived from several wild isolates to transform the wild-type androdioecious mating system into a dioecious mating system. By genotyping 375 single-nucleotide polymorphisms we show that the two populations had similar standing genetic diversity...

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