Recursos de colección

DEA @ DEENK (207.230 recursos)

Multidisciplinary repository to represent scientific life of the University of Debrecen and to archive regionally important documents of the Library.

Mostrando recursos 1 - 20 de 105

  1. Gastric cancer:clinics and treatment

    Farzin, Farnaz
    a descriptive study about gastric cancer , the classifications and d new approaches for the treatment

  2. Accelerated Partial Breast Irradiation

    Eigbe, Zion
    APBI has become the mainstay of breast cancer treatment. The short duration of therapy reduced total cost and positive result makes it a favourable option in the treatment of breast cancer.

  3. The use of gabapentin in anesthesiological practice

    Gabapentin is a structural analogue of gamma amino butyric acid (GABA),As this carrier-dependent transport is saturable, the bioavailability of gabapentin varies inversely with is thought to exert its action by interaction with a receptor associated with the L-system amino acid carrier protein.. Gabapentin has proved to be efficacious as an adjunct to other anticonvulsants in the treatment of partial seizures and generalised tonic-clonic seizures in patients over 12 years of age

  4. Pharmacological therapy in heart transplantation

    Said Elmi, Rahma
    The objective in this thesis will be about drugs given after heart transplantation. Today heart transplantation is the 3rd most common organ to transplant after kidney and lung. It is estimated that the need of transplantation of the heart is 10 folds more than what is transplanted in today’s society. Furthermore, I will emphasize the importance of new medication designed to increase the survival rate of the heart transplant. Today regenerative medicine is not fully developed when it comes to the heart as an organ, I will therefore discuss the impact that organ printing can have in the future when...

  5. Pharmacological Management of Parkinson's Disease

    Ingadóttir, Eva Lind
    Parkinson's disease is the second most common neurodegenerative disease with no known cure. In this thesis the currently available treatments for motor and non-motor symptoms of Parkinson's disease will be discussed, as well as emerging neuroprotective and disease modifying therapies.

  6. Pharmacological treatment of Duchenne and Becker muscular dystrophies

    Hamed, Rashidi
    Currently, there is no cure for muscular dystrophy. Treatment is generally aimed at controlling the onset of symptoms to maximize the quality of life. Medical therapy contains exon-skipping agents, utrophin upregulation, histone deacetylase inhibitors, corticosteroids, myostatin blockers, ataluren, and tyrosinekinase inhibitors. Exon skipping uses antisense oligonucleotides as a treatment for genetic diseases. The antisense oligonucleotides used for exon skipping are designed to bypass premature stop codons in the target RNA and restore reading frame disruption. Utrophin upregulation results improved sarcolemmal stability and prevents dystrophic pathology through a significant reduction of regeneration, necrosis and fibrosis.

  7. New trends in the treatment of Diabetes

    Afful, Ewurakua Kotaaba
    Greater than 360 million persons will develop diabetes by the year 2030. New Insulins analogues, adjunctive non-insulin therapies such as use of incretin agents and SGLT-2 inhibitors are being actively pursued as a novel approach in diabetes therapy. Pluripotent stem cells in the production of pancreatic progenitor or insulin producing cells in also being researched towards the treatment of type 1 diabetes. Information technology has also enabled care providers enhance care process, and provide aid to diabetics .

  8. Pharmacotherapy Of Acute Myeloid Leukemia

    Kim, Saebom
    AML is a clonal disorder of myeloid progenitors with the distinct features of clinical and biological heterogeneity. Chemotherapy has been a foundational management of AML in the past 40 years. It mainly consists of 2 phases : induction chemotherapy and consolidation therapy. Most tumor cells are rapidly eliminated and the patients put into a remission state in the remission induction phase. Consolidation is the intensive management after remission to get rid of the residual leukemic cells.

  9. Pharmacological Treatment of Alzheimer's Disease

    Waleed, Muhammad
    Dementia is one of the most common manifestations in the elderly in the western world. Although it can have various causes such as Vascular Dementia, Lewy body dementia, Parkinsonian dementia and frontotemporal dementia, the most common form of dementia is Alzheimer disease. It is no surprise that, as the life expectancy of the western world is increasing, the incidence of this disease is also increasing. This is primarily since it is a progressive disease whereby if the individual lives longer they have an increased risk of developing Alzheimer's disease. Unfortunately, there has been no cure for this disease and the...

  10. Role of p53 and PARP-1 in neurodegenerative diseases

    Seo, Woo Sung
    The thesis presents a general review of major neurodegenerative diseases and also discusses the role of p53 and PARP-1 in neurodegeneration. p53 and PARP-1 are 2 very essential proteins involved in cell-cycle regulation, cell death, DNA repair etc. Their role should be elucidated further to understand the pathomechanism but also protection against neurodegeneration.

  11. The chemotherapy of malaria with a focus on the pharmacology of artemisinins

    Mugamba, Viola
    The primary aim of the Thesis is to make a comprehensive overview on the essential members of drug classes frequently administered as therapeutic options in treatment of malaria infection with emphasis on artemisinins.

  12. Overview on Hemodynamic and Rheological Relations of Peripheral Vascular Graft Implanting

    Ariremako, Timothy Olufemi
    The aim of this thesis is to give a brief overview on peripheral vascular diseases and their treatment possibility, highlighting the surgical methods, and the hemodynamic and rheological effects of the graft implanting.

  13. Pharmacological treatment of allergic diseases

    Al khater, Zahra
    The thesis describes pharmacological treatment of allergic diseases , it emphasize the most common diseases including atopic dermatitis, allergic rhinitis and drug allergy, it also has brief description of the idea of allergy, epidemiology and history of allergy. it consists of the reaction that may contribute to develop an allergic disease

  14. Pharmacotherapy of Congestive Heart Failure

    Osaghae, God'sChoice Nosaze
    Congestive heart failure is a common disease with high mortality rate. This thesis exposes the pathophysiology, and most importantly the current treatment as well as the new therapies undergoing trials.

  15. Novel treatment in parkinson's disease

    Laniado, Matan
    In this work I tried to review some important disease related information and existing knowledge. In addition I have also tried to explore some new and promising treatments that might deal with the huge challenge facing the health systems worldwide. In the processes of focusing on the main issues, according to my point of view as medical student, I left many important disease related information outside the scope of the work.

  16. Modern treatment methods in Diabetes Mellitus type 2

    Truong, Dennis
    Diabetes type 2 is an endocrine metabolic disorder that is expanding in the modern world. The disease and its complications stands for a large portion of healthcare costs around the world today. Therefore it is important to treat the disease as optimal as possible and intervene before its onset. This thesis discusses the modern treatments that exists in healthcare today.

  17. Pharmacotherapy of Crohn’s Disease

    Iqbal, Kamran
    This thesis details the different treatment options for Crohn's disease and the pro's and con's of each category of drug used in treatment. Included is a short review of the history and pathophysiology of Crohn's disease as well as likely complications. Highlighted towards the end is newer therapies and some promising upcoming therapies like the mycobacterium parainfluenza virus vaccine.

  18. Non-invasive prenatal testing for chromosomal aneuploidies

    Joseph, Hazel Kristine
    The aim of this literature review is to give an overview of the conventional screening methods currently utilized for prenatal detection of chromosomal abnormalities and the development of non-invasive prenatal testing (NIPT) starting with the original discovery by Dennis Lo. The review will also try to summarize the different methods of cff-DNA based NIPTs for chromosomal aneuploidies (trisomy 21, 18 and 13) in the context of clinical experiences, efficacy, cost, ethics and limitations.

  19. The pharmacology of brentuximab bedouin

    Halldorsson, Benedikt
    Hodgkin's lymphoma is a tumor originating in white blood cells. Treatment with modern chemo- and radiotherapy has an excellent prognosis. Despite this fact, 15-20% of patients go into relapse. Brentuximb Vedotin is a monoclonal antibody against CD30. It is now being used in the treatment of refractory/relapsed Hodgkin's lymphoma.

  20. Celiac Disease - A Multifaceted And Puzzling Disorder

    Reynisdottir, Arna
    This summary of the scientific literature is to demonstrate the wide range of clinical manifestations of celiac disease, and the importance of early recognition of all to improve patient health and their quality of life. I would like to draw the attention to extraintestinal manifestations and diseases may be associated with celiac disease and suggest a multidisciplinary approach for this common, multifaceted, increasingly diagnostically complex, and lifelong autoimmune condition with a proven nutritional treatment.

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