Recursos de colección

Caltech Authors (160.918 recursos)

Repository of works by Caltech published authors.

Group = Resnick Sustainablility Instute

Mostrando recursos 1 - 3 de 3

  1. Catalytic Reduction of Alkyl and Aryl Bromides Using Isopropanol

    Haibach, Michael C.; Stoltz, Brian M.; Grubbs, Robert H.
    Milstein's complex (PNN)RuHCl(CO) catalyzes the efficient reduction of aryl and alkyl halides under relatively mild conditions, using isopropanol and a base. Sterically hindered tertiary and neopentyl substrates are reduced efficiently, as well as more functionalized aryl and alkyl bromides. The reduction process is proposed to occur via radical abstraction/hydrodehalogenation steps at ruthenium. Our research represents a safer and more sustainable alternative to typical silane, lithium aluminium hydride, and tin-based conditions for these reductions.
    (application/pdf) - 05-oct-2017

  2. Catalytic Reduction of Alkyl and Aryl Bromides Using Propan-2-ol

    Haibach, Michael C.; Stoltz, Brian M.; Grubbs, Robert H.
    Milstein's complex, (PNN)RuHCl(CO), catalyzes the efficient reduction of aryl and alkyl halides under relatively mild conditions by using propan-2-ol and a base. Sterically hindered tertiary and neopentyl substrates are reduced efficiently, as well as more functionalized aryl and alkyl bromides. The reduction process is proposed to occur by radical abstraction/hydrodehalogenation steps at ruthenium. Our research represents a safer and more sustainable alternative to typical silane, lithium aluminium hydride, and tin-based conditions for these reductions.
    (application/pdf; application/pdf) - 25-oct-2017

  3. Catalytic Reduction of Alkyl and Aryl Bromides Using Propan-2-ol

    Haibach, Michael C.; Stoltz, Brian M.; Grubbs, Robert H.
    Milstein's complex, (PNN)RuHCl(CO), catalyzes the efficient reduction of aryl and alkyl halides under relatively mild conditions by using propan-2-ol and a base. Sterically hindered tertiary and neopentyl substrates are reduced efficiently, as well as more functionalized aryl and alkyl bromides. The reduction process is proposed to occur by radical abstraction/hydrodehalogenation steps at ruthenium. Our research represents a safer and more sustainable alternative to typical silane, lithium aluminium hydride, and tin-based conditions for these reductions.
    (application/pdf; application/pdf) - 01-dic-2017

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