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SciELO - Scientific Electronic Library Online (52,285 recursos)
SciELO (Scientific Electronic Library Online) is an electronic library covering a selected collection of Brazilian scientific journals. The objective of the site is to implement an electronic virtual library, providing full access to a collection of serial titles, a collection of issues from individual serial titles, as well as to the full text of articles. The project envisages the development of a common methodology for the preparation, storage, dissemination and evaluation of scientific literature in electronic format.

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169. Introduction - Moqbel,Redwan

170. Foreword - Weller,Peter F

171. From allergy to schistosomes: role of Fc receptors and adhesion molecules in eosinophil effector function - Nutten,Sophie; Trottein,François; Gounni,Abdelillah Soussi; Papin,Jean-Paul; Capron,André; Capron,Monique
We have demonstrated that a new class of IgE receptors, FcepsilonRII/CD23, was involved in the functional duality of eosinophils and other proinflammatory cells.

172. The pro-allergic influences of helminth parasites - Pritchard,David I
Parasitic infection is highly allergenic, and the present paper illustrates how parasites might disrupt the regulation of IgE synthesis, resulting in heightened Th-2 responses.

173. Immunological system and Schistosoma mansoni: co-evolutionary immunobiology. What is the eosinophil role in parasite-host relationship? - Lenzi,Henrique L; Pacheco,Ronaldo G; Pelajo-Machado,Marcelo; Panasco,Mônica S; Romanha,Waldemiro S; Lenzi,Jane A
Schistosoma mansoni adult worms have capitalized on the apparent adversity of living within the mesenteric veins, using the dispersion of eggs and antigens to other tissues besides intestines to set a systemic activation of several haematopoietic lineages, specially eosinophils and monocytes/macrophages.

174. Bone marrow contribution to eosinophilic inflammation - Denburg,Judah A; Wood,Lorna; Gauvreau,Gail; Sehmi,Roma; Inman,Mark D; O'Byrne,Paul M
Allergen-induced bone marrow responses are observable in human allergic asthmatics, involving specific increases in eosinophil-basophil progenitors (Eo/B-CFU), measured either by hemopoietic assays or by flow cytometric analyses of CD34-positive, IL-3Ralpha-positive, and/or IL-5-responsive cell populations.

175. Modulatory role of eosinophils in allergic inflammation: new evidence for a rather outdated concept - Bandeira-Melo,Christianne; Cordeiro,Renato SB; Silva,Patrícia MR; Martins,Marco A
The eosinophilic response has been identified as a key alteration in the pathogenesis of asthma and other allergic diseases.

176. Immune responses of IL-5 transgenic mice to parasites and aeroallergens - Dent,LA; Daly,C; Geddes,A; Cormie,J; Finlay,DA; Bignold,L; Hagan,P; Parkhouse,RME; Garate,T; Parsons,J; Mayrhofer,G
Mice which constitutively over-express IL-5 have profound and life-long eosinophilia in a restricted number of tissues.

177. Interleukin-4 and interleukin-5 as targets for the inhibition of eosinophilic inflammation and allergic airways hyperreactivity - Foster,Paul S; Hogan,Simon P; Matthaei,Klaus I; Young,Ian G
Clinical and experimental investigations suggest that allergen-specific CD4+ T-cells, IgE and the cytokines IL-4 and IL-5 play central roles in initiating and sustaining an asthmatic response by regulating the recruitment and/or activation of airways mast cells and eosinophils.

178. The role of interleukin-5 (IL-5 ) in vivo: studies with IL-5 deficient mice - Matthaei,Klaus I; Foster,Paul S; Young,Ian G
Since interleukin5 (IL5) is believed to regulate the growth, differentiation and activation of eosinophils (Coffman et al.

179. Pulmonary biology of anti-interleukin 5 antibodies - Egan,RW; Athwahl,D; Chou,C-C; Chapman,RW; Emtage,S; Jenh,C-H; Kung,TT; Mauser,PJ; Murgolo,NJ; Bodmer,MW
Interleukin 5 (IL-5) is a critical cytokine for the maturation of eosinophil precursors to eosinophils in the bone marrow and those eosinophils then accumulate in the lungs during asthma.

180. IL-5 and IL-5 receptor in asthma - Kotsimbos,ATC; Hamid,Q
In chronic parasitic disease and in chronic allergic disease, IL-5 is predominantly a T cell derived cytokine which is particularly important for the terminal differentiation, activation and survival of committed eosinophil precursors.

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