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SciELO - Scientific Electronic Library Online (52,375 recursos)
SciELO (Scientific Electronic Library Online) is an electronic library covering a selected collection of Brazilian scientific journals. The objective of the site is to implement an electronic virtual library, providing full access to a collection of serial titles, a collection of issues from individual serial titles, as well as to the full text of articles. The project envisages the development of a common methodology for the preparation, storage, dissemination and evaluation of scientific literature in electronic format.

Mostrando recursos 181 - 200 de 1,776

181. The enigmatic eosinophil: investigation of the biological role of eosinophils in parasitic helmint infection - Ovington,Karen S; Behm,Carolyn A
Many experimental investigations have shown that the eosinophilia is induced by interleukin-5 (IL-5) but its functional significance remains unclear.

182. The debate over the effector function of eosinophils in helminth infection: new evidence from studies on the regulation of vaccine immunity by IL-12 - Wynn,Thomas A
The production of Th1-type cytokines is associated with strong cell-mediated immunity while Th2-type cytokines are typically involved in the generation of humoral immune responses.

183. Cytokines in the modulation of eosinophilia - Faccioli,Lúcia H; Vargaftig,BB; Medeiros,Alexandra I; Malheiros,Adriana
In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis.

184. Signal transduction and activation of the NADPH oxidase in eosinophils - Lindsay,Mark A; Giembycz,Mark A
Activation of the eosinophil NADPH oxidase and the subsequent release of toxic oxygen radicals has been implicated in the mechanism of parasite killing and inflammation.

185. Eokines: synthesis, storage and release from human eosinophils - Lacy,P; Moqbel,R
Eosinophils are prominent inflammatory cells in asthma and other allergic disorders, as well as in helminthic parasite infections.

186. Mechanisms of formation and function of eosinophil lipid bodies: inducible intracellular sites involved in arachidonic acid metabolism - Bozza,Patricia T; Yu,Wengui; Weller,Peter F
Lipid bodies, inducible lipid-rich cytoplasmic inclusions, are characteristically abundant in cells associated with inflammation, including eosinophils.

187. Modulation by IL-10 of antigen-induced allergic responses in mice - Zuany-Amorim,Claudia; Vargaftig,B Boris; Pretolani,Marina
Over the last few years, we examined the anti-allergic properties of interleukin (IL)-10 in different models of inflammation in the mouse, as well as against IgE-dependent activation of mouse bone marrow-derived mast cells (BMMC).

188. Role of the cyclosporin-sensitive transcription factor NFAT1 in the allergic response - Viola,João PB; Rao,Anjana
Proteins belonging to the NFAT (nuclear factor of activated T cells) family of transcription factors are expressed in most immune cell types, and play a central role in the transcription of cytokine genes, such as IL-2, IL-4, IL-5, IL-13, IFN-gamma, TNF-alpha, and GM-CSF.

189. Expression and function of b1 integrins on human eosinophils - Seminario,Maria-Cristina; Bochner,Bruce S
One possible mechanism for selective eosinophil recruitment involves the alpha4beta 1 (VLA-4) integrin which is not expressed on neutrophils.

190. Systemic modulation of peripheral eosinophilia (air pouch model) in Schistosoma mansoni infection - Pacheco,RG; Lenzi,HL
Schistosoma mansoni infection induces in their hosts a marked and sustained eosinophilia, which is influenced or modulated by complex mechanisms, that vary according to the phase of infection.

191. Human eosinophil-lymphocyte interactions - Weller,Peter F; Lim,Kaiser
While the eosinophil's effector functions clearly can contribute to the pathogenesis of allergic diseases, the evolutionary benefit to having eosinophils as a distinct class of leukocytes is not clear, especially if one must reconsider the nominally beneficial role of eosinophils in parasite host defense.

192. The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation - Conroy,Dolores M; Humbles,Alison A; Rankin,Sara M; Palframan,Roger T; Collins,Paul D; Griffiths-Johnson,David A; Jose,Peter J; Williams,Timothy J
We have recently discovered a novel eosinophil-selective chemoattractant which we called eotaxin in an animal model of allergic airways disease.

193. A comparison of the inhibitory activity of selective PDE4 inhibitors on eosinophil recruitment in guinea pig skin - Teixeira,Mauro M; Miotla,JM; Cooper,N; Gristwood,RW; Hellewell,PG
We have previously shown that systemic treatment with the PDE4 inhibitor rolipram effectively inhibt eosinophil migration in guinea pig skin.

194. A role for lymphocytes and cytokines on the eosinophil migration induced by LPS - Castro-Faria-Neto,Hugo C; Penido,Carmen M; Larangeira,Andréa P; Silva,Adriana R; Bozza,Patrícia T
This phenomenon is preceded by a neutrophil influx and accompanied by lymphocyte and monocyte accumulation.

195. Effect of selective phosphodiesterase inhibitors on the rat eosinophil chemotactic response in vitro - Alves,Alessandra C; Pires,Ana Lucia A; Lagente,Vincent; Cordeiro,Renato SB; Martins,Marco A; Silva,Patricia MR e
The effect of the analogues N6-2'-O-dibutyryladenosine 3':5' cyclic monophosphate (Bt2 cyclic AMP) and N2-2'-O- dibutyrylguanosine 3':5' cyclic monophosphate (Bt2 cyclic GMP) has also been determined.

196. Participation of interleukin-5, interleukin-8 and leukotriene B4 in eosinophil accumulation in two different experimental models - Oliveira,Sandra HP; Faccioli,Lúcia H; Ferreira,Sérgio H; Cunha,Fernando Q
There are several experimental models describing in vivo eosinophil (EO) migration, including ip injection of a large volume of saline (SAL) or Sephadex beads (SEP).

197. Description of an in vivo model for the assessment of eosinophil chemoattractants in the mouse - Teixeira,Mauro M; Williams,Timothy J; Hellewell,Paul G
Chemokines (chemoattractant cytokines) induce potent and selective chemotaxis of leukocyte subsets in vitro.

198. A new murine model of persistent lung eosinophilic inflammation - Russo,Momtchilo; Mariano,Mario; Jancar,Sonia
We summarize here the main characteristics of a novel model of pulmonary hypersensitivity.

199. Antigen-induced pleural eosinophilia is suppressed in diabetic rats: role of corticosteroid hormones - Diaz,Bruno L; Serra,Magda F; Barreto,Emiliano O; Cordeiro,Renato SB; Martins,Marco A; Silva,Patricia MR e
In this study, we have investigated whether endogenous corticosteroids could be implicated in the hyporeactivity to antigen challenge observed in sensitized diabetic rats.

200. Role of eosinophilic airway inflammation in models of asthma - Lapa e Silva,José R; Ruffié,C; Lefort,J; Pretolani,M; Vargaftig,BB
Eosinophils play a central role in the establishment and outcome of bronchial inflammation in asthma.

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