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arXiv (509,308 recursos)
This is one of the most extensive subject based repositories in the world in the field of physics, mathematics, astronomy, computer sciences and quantitative biology. This is the principal site with almost 20 mirror versions around the globe. The site is supported by an extensive collection of information and background documentation. An RSS feed is available for anyone interested in keeping up-to-date with newly added materials.

Mostrando recursos 141 - 160 de 4,680

141. Graph theoretic analysis of protein interaction networks of eukaryotes - Goh, K. -I.; Kahng, B.; Kim, D.
Thanks to recent progress in high-throughput experimental techniques, the datasets of large-scale protein interactions of prototypical multicellular species, the nematode worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster, have been assayed.

142. Mechanical unfolding of RNA hairpins - Hyeon, Changbong; Thirumalai, D.
Mechanical unfolding trajectories, generated by applying constant force in optical tweezer experiments, show that RNA hairpins and the P5abc subdomain of the group I intron unfold reversibly.

143. Gene Algebra from a Genetic Code Algebraic Structure - Sanchez, Robersy; Morgado, Eberto; Grau, Ricardo
The biological distinction between the base positions in the codon, the chemical types of bases (purine and pyrimidine) and their hydrogen bond number have been the most relevant codon properties used in the genetic code analysis.

144. Uni-directional polymerization leading to homochirality in the RNA world - Nilsson, M.; Brandenburg, A.; Andersen, A. C.; Hoefner, S.
The differences between uni-directional and bi-directional polymerization are considered.

145. Functional modes of proteins are among the most robust ones - Nicolay, Samuel; Sanejouand, Yves-Henri
It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models.

146. Density-Dependence as a Size-Independent Regulatory Mechanism - de Vladar, Harold P.
The growth function of populations is central in biomathematics.

147. Implications of Aging in Bacteria - Johnson, Leah R.; Mangel, Marc
Motivated by recent research of aging in E.

148. Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics - Brusch, Lutz; Cuniberti, Gianaurelio; Bertau, Martin
Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity.

149. Prediction of site-specific amino acid distributions and limits of divergent evolutionary changes in protein sequences - Porto, Markus; Roman, H. Eduardo; Vendruscolo, Michele; Bastolla, Ugo
We derive an analytic expression for site-specific stationary distributions of amino acids from the Structurally Constrained Neutral (SCN) model of protein evolution with conservation of folding stability.

150. An Unusual 500,000 Bases Long Oscillation of Guanine and Cytosine Content in Human Chromosome 21 - Li, Wentian; Holste, Dirk
An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21.

151. Universal 1/f noise, cross-overs of scaling exponents, and chromosome specific patterns of GC content in DNA sequences of the human genome - Li, Wentian; Holste, Dirk
We find that (i) the 1/f^alpha decay is universally observed in the power spectra of all twenty-four chromosomes, and that (ii) the exponent alpha \approx 1 extends to about 10^7 bases, one order of magnitude longer than what has previously been observed.

152. Spectral Analysis of Guanine and Cytosine Fluctuations of Mouse Genomic DNA - Li, Wentian; Holste, Dirk
We study global fluctuations of the guanine and cytosine base content (GC%) in mouse genomic DNA using spectral analyses.

153. Model for the robust establishment of precise proportions in the early Drosophila embryo - Aegerter-Wilmsen, Tinri; Aegerter, Christof M.; Bisseling, Ton
As an early pattern formation step in Drosophila embryos, an anterior-posterior gradient of Bicoid (Bcd) induces hunchback (hb) expression (Driever et al.

154. Combinatorial complexity and dynamical restriction of network flows in signal transduction - Faeder, James R.; Blinov, Michael L.; Goldstein, Byron; Hlavacek, William S.
Here, using a computational model that accounts for 307 molecular species implied by specified interactions of four proteins involved in signalling by the immunoreceptor Fc$\epsilon$RI, we determine the relative importance of molecular species that can be generated during signalling, chemical transitions among these species, and reaction paths that lead to activation of the protein tyrosine kinase (PTK) Syk.

155. A Phenomenological model of Myosin II dynamics in the presence of external loads - Buonocore, A.; Caputo, L.; Ishii, Y.; Pirozzi, E.; Yanagida, T.; Ricciardi, L. M.
We address the controversial hot question concerning the validity of the loose coupling versus the lever-arm theories in the actomyosin dynamics by re-interpreting and extending the phenomenological washboard potential model proposed by some of us in a previous paper.

156. Predicting Genetic Regulatory Response Using Classification - Middendorf, Manuel; Kundaje, Anshul; Wiggins, Chris; Freund, Yoav; Leslie, Christina
We present a novel classification-based method for learning to predict gene regulatory response.

157. Neurokinematic Modeling of Complex Swimming Patterns of the Larval Zebrafish - Hill, Scott A.; Liu, Xiao-Ping; Borla, Melissa A.; Jose, Jorge V.; O'Malley, Donald M.
Larval zebrafish exhibit a variety of complex undulatory swimming patterns.

158. Signal processing of acoustic signals in the time domain with an active nonlinear nonlocal cochlear model - Lamar, M. D.; Xin, J.; Qi, Y.
A two space dimensional active nonlinear nonlocal cochlear model is formulated in the time domain to capture nonlinear hearing effects such as compression, multi-tone suppression and difference tones.

159. An Information-Theoretic Approach to Network Modularity - Ziv, Etay; Middendorf, Manuel; Wiggins, Chris
Exploiting recent developments in information theory, we propose, illustrate, and validate a principled information-theoretic algorithm for module discovery and resulting measure of network modularity.

160. MultiNeuron - Neural Networks Simulator For Medical, Physiological, and Psychological Applications - Gorban, A. N.; Rossiyev, D. A.; Dorrer, M. G.
This work describes neural software applied in medicine and physiology to: investigate and diagnose immune deficiencies; diagnose and study allergic and pseudoallergic reactions; forecast emergence or aggravation of stagnant cardiac insufficiency in patients with cardiac rhythm disorders; forecast development of cardiac arrhythmia after myocardial infarction; reveal relationships between the accumulated radiation dose and a set of immunological, hormonal, and bio-chemical parameters of human blood and find a method to be able to judge by these parameters the dose value; propose a technique for early diagnosis of chor-oid melanomas; Neural networks also help to predict human relations within a group.

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