arXiv
(509,308 recursos)
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163.
Why high-error-rate random mutagenesis libraries are enriched in
functional and improved proteins - Drummond, D. Allan; Iverson, Brent L.; Georgiou, George; Arnold, Frances H.
Recently, several groups have used error-prone polymerase chain reactions to
construct mutant libraries containing up to 27 nucleotide mutations per gene on
average, and reported a striking observation: although retention of protein
function initially declines exponentially with mutations as has previously been
observed, orders of magnitude more proteins remain viable at the highest
mutation rates than this trend would predict.
164.
Native geometry and the dynamics of protein folding - Faisca, P. F. N.; da Gama, M. M. Telo
In this paper we investigate the role of native geometry on the kinetics of
protein folding based on simple lattice models and Monte Carlo simulations.
165.
Systematic identification of abundant A-to-I editing sites in the human
transcriptome - Levanon, Erez Y.; Eisenberg, Eli; Yelin, Rodrigo; Nemzer, Sergey; Hallegger, Martina; Shemesh, Ronen; Fligelman, Zipora Y.; Shoshan, Avi; Pollock, Sarah R.; Sztybel, Dan; Olshansky, Moshe; Rechavi, Gideon; Jantsch, Michael F.
RNA editing by members of the double-stranded RNA-specific ADAR family leads
to site-specific conversion of adenosine to inosine (A-to-I) in precursor
messenger RNAs.
168.
Cognitive styles sex the brain, compete neurally, and quantify deficits
in autism - Goldenfeld, Nigel; Wheelwright, Sally; Baron-Cohen, Simon
Methods: Two questionnaires, the Systemizing Quotient (SQ) and the Empathy
Quotient (EQ), were administered to a normal control group and a group of
individuals with Asperger Syndrome (AS) or High-Functioning Autism (HFA).
171.
Transcriptional Regulation by the Numbers 1: Models - Bintu, Lacramioara; Buchler, Nicolas E.; Garcia, Hernan G.; Gerland, Ulrich; Hwa, Terence; Kondev, Jane'; Phillips, Rob
The study of gene regulation and expression is often discussed in
quantitative terms.
172.
Transcriptional Regulation by the Numbers 2: Applications - Bintu, Lacramioara; Buchler, Nicolas E.; Garcia, Hernan G.; Gerland, Ulrich; Hwa, Terence; Kondev, Jane'; Kuhlman, Thomas; Phillips, Rob
The thermodynamic models
reviewed in the preceding paper provide a useful framework for the quantitative
analysis of bacterial transcription regulation.
176.
The dynamics of the min proteins of Escherichia coli under the constant
external fields - Kanthang, Paisan; Ngamsaad, Waipot; Modchang, Charin; Triampo, Wannapong; Nuttawut, Narin; Tang, I-Ming; Lenbury, Yongwimol
Exposure to a constant external
field e.g., an electric field or magnetic field may cause the bacteria cell
division mechanism to change resulting in an abnormal cytokinesis.
180.
Love before Sex - Abdullah, Wan Ahmad Tajuddin Wan
Much has been debated about the benefit of sexual over asexual reproduction
in terms of evolutionary fitness.
161.
