Mostrando recursos 1 - 20 de 130
Smyth, Katherine Marie
Next generation medical imaging technology hinges on the development of cost effective and array compatible transducers making piezoelectric micro-machined ultrasonic transducers (pMUTs) an attractive alternative to the current bulk piezoelectric technology. This thesis aims to realize pMUT potential starting with the development of an effective single cell model that is further scaled to optimize multi-cell elements in a 1D array. In the first half of this work, a transverse mode, lead zirconate titanate (PZT) pMUT plate cell is fabricated using common micro-fabrication techniques and a PZT sol-gel deposition process. Through derivation using a novel Greens function solution technique, an equivalent...
Optical Frequency Mixing Through Nanoantenna Enhanced Difference Frequency Generation: Metatronic Mixer
Chettiar, Uday K; Engheta, Nader
A design for a subwavelength all-optical frequency mixer is proposed. The method relies on enhanced difference-frequency generation, which is achieved in two steps with the help of plasmonic nanoantennas. The interaction of the two input signals with the nonlinear material is increased through the use of input nanoantennas, which focus the incident energy of two different frequencies onto the nanoparticle formed by a nonlinear material. Next, the difference-frequency emission is enhanced through the Purcell effect by the use of a separate output nanoantenna that is resonant at the difference frequency. The application of this twofold approach allows for a significant...
Lynn, Michael (Michael Benjamin)
Organisms have a remarkable ability to respond to complex sensory inputs with intricate, tuned motor patterns. How does the brain organize and tune these motor responses, and are certain circuit architectures, or connectivity patterns, optimally suited for certain sensorimotor applications? This thesis presents progress towards this particular problem in three subprojects. The first section re-analyzes a large data set of single-unit recordings in zebra finch area HVC during singing. While HVC is known to be essential for proper expression of adult vocalization, its circuit architecture is contentious. Evidence is presented against the recently postulated gesture-trajectory extrema hypothesis for the organization...
McCaughan, Adam N.; Berggren, Karl K.
Superconducting electronics based on Josephson junctions are used to sense and process electronic signals with minimal loss; however, they are ultrasensitive to magnetic fields, limited in their amplification capabilities, and difficult to manufacture. We have developed a 3-terminal, nanowire-based superconducting electrothermal device which has no Josephson junctions. This device, which we call the nanocryotron, can be patterned from a single thin film of superconducting material with conventional electron-beam lithography. The nanocryotron has a demonstrated gain of >20, can drive impedances of 100 kΩ, and operates in typical ambient magnetic fields. We have additionally applied it both as a digital logic...
Back-propagation operation for analog neural network hardware with synapse components having hysteresis characteristics.
Michihito Ueda; Yu Nishitani; Yukihiro Kaneko; Atsushi Omote
To realize an analog artificial neural network hardware, the circuit element for synapse function is important because the number of synapse elements is much larger than that of neuron elements. One of the candidates for this synapse element is a ferroelectric memristor. This device functions as a voltage controllable variable resistor, which can be applied to a synapse weight. However, its conductance shows hysteresis characteristics and dispersion to the input voltage. Therefore, the conductance values vary according to the history of the height and the width of the applied pulse voltage. Due to the difficulty of controlling the accurate conductance,...
The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression.
Nathan T Mortimer; Kenneth H Moberg
The Drosophila melanogaster gene archipelago (ago) encodes the F-box/WD-repeat protein substrate specificity factor for an SCF (Skp/Cullin/F-box)-type polyubiquitin ligase that inhibits tumor-like growth by targeting proteins for degradation by the proteasome. The Ago protein is expressed widely in the fly embryo and larva and promotes degradation of pro-proliferative proteins in mitotically active cells. However the requirement for Ago in post-mitotic developmental processes remains largely unexplored. Here we show that Ago is an antagonist of the physiologic response to low oxygen (hypoxia). Reducing Ago activity in larval muscle cells elicits enhanced branching of nearby tracheal terminal cells in normoxia. This tracheogenic...
Leung-Hang Ma; Beena Punnamoottil; Silke Rinkwitz; Robert Baker
To better understand how individual genes and experience influence behavior, the role of a single homeotic unit, hoxb4a, was comprehensively analyzed in vivo by clonal and retrograde fluorescent labeling of caudal hindbrain neurons in a zebrafish enhancer-trap YFP line. A quantitative spatiotemporal neuronal atlas showed hoxb4a activity to be highly variable and mosaic in rhombomere 7-8 reticular, motoneuronal and precerebellar nuclei with expression decreasing differentially in all subgroups through juvenile stages. The extensive Hox mosaicism and widespread pleiotropism demonstrate that the same transcriptional protein plays a role in the development of circuits that drive behaviors from autonomic through motor function...
Hongjuan Zhang; Yu Wang; Xu Zhang; Dong Wang; Baoquan Jin
In flammable or explosive environments, an ultrasonic sensor for distance measurement poses an important engineering safety challenge, because the driving circuit uses an intermediate frequency transformer as an impedance transformation element, in which the produced heat or spark is available for ignition. In this paper, an intrinsically safe ultrasonic ranging sensor is designed and implemented. The waterproof piezoelectric transducer with integrated transceiver is chosen as an energy transducing element. Then a novel transducer driving circuit is designed based on an impedance matching method considering safety spark parameters to replace an intermediate frequency transformer. Then, an energy limiting circuit is developed...
Lago Costas, Alfredo Alberto
En la Península Ibérica se está viviendo un fenómeno emergente en el panorama deportivo: el auge del Parkour, deporte urbano que se sirve de la morfología de la ciudad aprovechando elementos del mobiliario, escaleras, desniveles y rampas para realizar circuitos y piruetas. Al tratarse de un deporte relativamente nuevo existe una falta de estudio de la relación del deporte con el entorno urbano. Es por ello que tampoco existen muchas construcciones a día de hoy que conjuguen las necesidades del parkour con la morfología y circuitos urbanos. La ciudad de Vigo tiene un papel destacable dentro de la comunidad gallega, debido...
ABOUT TRACK CIRCUIT CALCULATION METHOD DEPENDENT ON FERROMAGNET PROPERTIES IN CONDITIONS OF TRACTION CURRENT NOISE INFLUENCE
A. Yu. Zhuravlev
Purpose. The work is intended to investigate the electromagnetic processes in impedance bond in order to improve noise immunity of track circuits (TC) for safe railway operation. Methodology. To achieve this purpose the methods of scientific analysis, mathematical modelling, experimental study, a large-scale simulation were used. Findings. The work examined the interference affecting the normal performance of track circuits. To a large extent, part of track circuit damages account for failures in track circuit equipment. Track circuit equipment is connected directly to the track line susceptible to traction current interference, which causes changes in its electrical characteristics and electromagnetic properties....
A Novel Field-Circuit FEM Modeling and Channel Gain Estimation for Galvanic Coupling Real IBC Measurements
Yue-Ming Gao; Zhu-Mei Wu; Sio-Hang Pun; Peng-Un Mak; Mang-I Vai; Min Du
Existing research on human channel modeling of galvanic coupling intra-body communication (IBC) is primarily focused on the human body itself. Although galvanic coupling IBC is less disturbed by external influences during signal transmission, there are inevitable factors in real measurement scenarios such as the parasitic impedance of electrodes, impedance matching of the transceiver, etc. which might lead to deviations between the human model and the in vivo measurements. This paper proposes a field-circuit finite element method (FEM) model of galvanic coupling IBC in a real measurement environment to estimate the human channel gain. First an anisotropic concentric cylinder model of...
Xin Gao; Tongyu Wu; Kirby D. Johnson; Jamie L. Lahvic; Erik A. Ranheim; Leonard I. Zon; Emery H. Bresnick
Hematopoietic stem cells (HSCs) originate from hemogenic endothelium within the aorta-gonad-mesonephros (AGM) region of the mammalian embryo. The relationship between genetic circuits controlling stem cell genesis and multi-potency is not understood. A Gata2 cis element (+9.5) enhances Gata2 expression in the AGM and induces the endothelial to HSC transition. We demonstrated that GATA-2 rescued hematopoiesis in +9.5−/− AGMs. As G-protein-coupled receptors (GPCRs) are the most common targets for FDA-approved drugs, we analyzed the GPCR gene ensemble to identify GATA-2-regulated GPCRs. Of the 20 GATA-2-activated GPCR genes, four were GATA-1-activated, and only Gpr65 expression resembled Gata2. Contrasting with the paradigm in which GATA-2-activated...
System-Level Coupled Modeling of Piezoelectric Vibration Energy Harvesting Systems by Joint Finite Element and Circuit Analysis
Congcong Cheng; Zhongsheng Chen; Hongwu Shi; Ziniu Liu; Yeping Xiong
A practical piezoelectric vibration energy harvesting (PVEH) system is usually composed of two coupled parts: a harvesting structure and an interface circuit. Thus, it is much necessary to build system-level coupled models for analyzing PVEH systems, so that the whole PVEH system can be optimized to obtain a high overall efficiency. In this paper, two classes of coupled models are proposed by joint finite element and circuit analysis. The first one is to integrate the equivalent circuit model of the harvesting structure with the interface circuit and the second one is to integrate the equivalent electrical impedance of the interface...
PRINCIPLES OF IMPLEMENTATION OF CURRENT PROTECTION FROM INTERPHASE SHORT-CIRCUITS ON THE POWER LINES WITH UNILATERAL FEED
F. A. Romaniuk; M. A. Shevaldin
The article describes the implementation of the principle of overcurrent protection from interphase short-circuits on the power lines with unilateral feed. The expression of the detection of the fault location by the relative value of the distance from the installation of pro- tection to the point of damage with the help of the results of operational control of the short- circuit current damaged phases has been suggested in the article. Also the expression for determining the time delay response for such protection has been presented, taking into account fault location that had been detected.
The paper proposes and describes the...
Estudio de fenómenos transitorios en circuitos eléctricos de primer orden; Study of transient phenomena in first order circuits
Bertha María Soriano González; Frank Grau Merconchini; Llohandry Cruz Carnero
Este trabajo expone una metodología para estudiar procesos transitorios de corriente alterna y directa, en circuitos eléctricos lineales con un solo elemento almacenador de energía, empleando un sistema de instrumentación con una computadora y una tarjeta de adquisición de datos que permitió generar un tren de pulsos para sustituir los dispositivos de conexión y desconexión de la fuente. Se presentan los modelos matemáticos de los procesos transitorios, en presencia del tren de pulsos y para la combinación de este en serie con una fuente de señal sinusoidal; así como el diseño, la implementación de la práctica de laboratorio y las...
Leonardo Casas Fernández; Jorge Adrián Leyva Jassa
Tradicionalmente, los cálculos relacionados con las redes de distribución se apoyan en numerosas
aproximaciones debido fundamentalmente a la dificultad de obtener datos confiables y a las simplificaciones
hechas para realizarlos. En este artículo se valora la representación de cada elemento de estos circuitos
con el fin de obtener respuestas lo más exactas posible en los estudios de los circuitos de distribución
primaria. Basado en las ideas expuestas para reducir al mínimo las simplificaciones, se ha desarrollado
RADIAL, un sistema de computación que garantiza alta fiabilidad, con el cual es posible alcanzar resultados
de alta calidad vinculados con los problemas más...
A. Ursu; G. Gruita; S. Zaporojan
A design method of sequential system automata using temporal logic specifications is proposed in this paper. The method is based on well-known Z.Manna and P.Wolper temporal logic satisfiability analysis procedure  and is extended to include past time temporal operators. A new specification method which uses temporal equivalence classes is proposed to specify the behaviour of large digital circuits. The impact of the composition and decomposition operations of the temporal equivalence classes on the final automata has been studied. A case study is carried out which deals with the design of the synchronous bus arbiter circuit element. The SMV tool...
Oscillations in fast-spiking neurons that express parvalbumin may be involved in information processing, and may be deficient in neural circuit pathologies including schizophrenia. However, it has not been possible to demonstrate a quantitative impact of this oscillatory system on information processing. Here we use dynamic clamp and optogenetic tools to deconstruct the pyramidal cell- parvalbumin interneuron microcircuit, and information theory to measure how oscillations affect the function of each circuit element.
First, we studied how oscillations affect single neocortical pyramidal neurons. Using dynamic clamp, we stimulated neocortical pyramidal neurons with trains of simulated excitatory post-synaptic currents (sEPSCs)....
To date, a wide range of neural electrodes have been used in basic neuroscience and neural prosthetic research (brain machine interfaces). Polymeric microprobes have received a great deal of attention owing to their simple fabrication process, flexibility and biocompatibility. Implantable neural probes for neuroscience and brain machine interfaces are generally preferred to have a minimum footprint as possible to minimize neural damage. Alternatively, a superconducting field effect transistor (SuFET) based neurotransducer with carbon nanotubes (CNT) or pickup coil (PC) kind of input circuit for the nerve and neuron impulse has been designed. A nanoSuFET with a high-temperature superconducting channel is...
G. Ya. Khachikyan; N. S. Zhakupov; N. Zh. Kadyrkhanova
An earthquake is an element of the global electric circuit (GEC) – this new idea suggested in the space age is tested in our study. In the frame of the GEC concept, one may expect that tectonic structures of the northern and southern hemispheres may be magnetically conjugated. It is found that the midocean ridges of the southern hemisphere, located along the boundary of the Antarctic lithosphere plate, are magnetically conjugated with the areas of the junction of continental orogens and platforms in the northern hemisphere. The closest geomagnetic conjugacy exists between the southern boundary of Nazca lithospheric plate and...