Mostrando recursos 1 - 20 de 310.759

  1. Combining Text Mining and Data Visualization Techniques to Understand Consumer Experiences of Electronic Cigarettes and Hookah in Online Forums

    Annie T. Chen; Shu-hong Zhu; Mike Conway
    Our aim in this work is to apply text mining and novel visualization techniques to textual data derived from online health discussion forums in order to better understand consumers ’ experiences and perceptions of electronic cigarettes and hookah.

  2. Correspondence: Sigrun Alba

    Sigrun Alba Johannesdottir; Erzsébet Horváth-puhó; Vera Ehrenstein; Morten Schmidt; Lars Pedersen; Henrik Toft Sørensen
    Abstract: The Danish health care system provides partial reimbursement of most prescription medications in Denmark. The dispensation of prescription medications is registered in admin-istrative databases. Each time a prescription is redeemed at a pharmacy, an electronic record is generated with information related to the user, prescriber, the pharmacy, and the dispensed drug. The National Health Service gathers this information for administration of the drug reimburse-ment plan. Recently, this information became the basis for the establishment of a new research database, the Danish National Database of Reimbursed Prescriptions (DNDRP). In this paper, we review the content, coverage, quality, linkage, access, and...

  3. The Past, Present, and Future of Image-Enhanced Endoscopy

    Clin Endosc; Jae-young Jang; Clin Endosc
    Despite the remarkable progress recently made to enhance the resolution of white-light endoscopy, detection, and diagnosis of premalignant lesions, such as adenomas and subtle early-stage cancers, remains a great challenge. As for example, although chromoendoscopy, such as endoscopy using indigo carmine, is useful for the early diagnosis of subtle lesions, the technique presents various disadvantages ranging from the time required for spray application of the dye and suctioning of excess dye to the increased difficulty in identifying lesions in the presence of severe inflammation and obstruction of visual field due to the pooling of solution in depressed-type lesions. To overcome...

  4. Electronic supplementary material is available

    Moir Ca; Christopher H. Eskiw; Concordance Between; Brett Trost; Catherine A. Moir; Zoe E. Gillespie; Anthony Kusalik; Jennifer A. Mitchell; Christopher H. Eskiw
    Concordance between RNA-sequencing data and DNAmicroarray data in transcriptome analysis of proliferative and quiescent fibroblasts. R. Soc. open sci. 2: 150402.

  5. Genomic conseque e pe L


    ec eno re, 86 ema ing hic yb fre es its s d nc 1. INTR New sp overlap differen mode a tion re geograp homog of allo geograp quence increas lations occur to stron ents or instanc [8–11] taxa m speciat selectio contact [12–14 tation chan-iation sefully across it and many nomic eco-vance and geno-age of gically risons nomic g the re still an be fected many tiation ways. Speciation with gene flow, either primary or following sec-ondary contact, might be characterized by divergence in only a few regions that harbour genes under strong diver-gent selection and those causing...

  6. rspb.royalsocietypublishing.org

    Jasienska G; Heidi Colleran
    behaviour, evolution, ecology Community-level education accelerates the cultural evolution of fertility decline a smaller family size as average education in the community increased—Electronic supplementary material is available

  7. Analytic Challenges Arising from the STOP CRC Trial: Pragmatic

    William M. Vollmer; Beverly B. Green; Gloria D. Coronado
    This Methods Case Study is brought to you for free and open access by the the Publish at EDM Forum Community. It has been peer-reviewed and accepted for publication in eGEMs (Generating Evidence & Methods to improve patient outcomes). The Electronic Data Methods (EDM) Forum is supported by the Agency for Healthcare Research and Quality (AHRQ), Grant 1U18HS022789-01. eGEMs publications do not reflect the official views of AHRQ or the United States Department of Health and Human Services.

  8. Research Data Explorer: Lessons Learned in Design and Development of Context-based Cohort Definition and Selection

    Adam Wilcox Phd; David Vawdrey; Chunhua Weng; Mark Velez; Suzanne Bakken; Rn Dnsc
    Research Data eXplorer (RedX) was designed to support self-service research data queries and cohort identification from clinical research databases. The primary innovation of RedX was the electronic health record view of patient data, to provide better contextual understanding for non-technical users in building complex data queries. The design of RedX around this need identified multiple functions that would use individual patient views to better understand population-based data, and vice-versa. During development, the more necessary and valuable components of RedX were refined, leading to a functional self-service query and cohort identification tool. However, with the improved capabilities and extensibility of other...

  9. A Novel Point-of-Care BioNanoSensor for Rapid HIV Detection and Treatment Monitoring

    Tomasz Rozmyslowicz; Johann Desa; Ryszard Lec; Glen N Gaulton
    We report here a new diagnostic approach to the direct detection of HIV in blood or other body fluids that is rapid, sensitive and potentially applicable in a point-of-care setting. The approach follows on the development of a novel BioNanoSensor (BNS) device that utilizes piezoelectric technology to detect the presence of the HIV surface glycoprotein gp120 in a nanoscale format. The detection range of the BNS device for the biomarker gp120 displayed a low-end sensitivity of 6.5×104 HIV viral particles/ml, while using a small fluid sample (5 µl) and with a reaction time of less then 30 seconds. Performance of...

  10. PROCEEDINGS Open Access

    Alex Lencioni; Laura Hutchins; Y Annis; Wanchi Chen; Emre Ermisoglu; Zhidan Feng; Karen Mack; Kacie Simpson; Cheryl Lane; Umit Topaloglu
    Background: Comprehensive capture of Adverse Events (AEs) is crucial for monitoring for side effects of a therapy while assessing efficacy. For cancer studies, the National Cancer Institute has developed the Common Terminology Criteria for Adverse Events (CTCAE) as a required standard for recording attributes and grading AEs. The AE assessments should be part of the Electronic Health Record (EHR) system; yet, due to patient-centric EHR design and implementation, many EHR’s don’t provide straightforward functions to assess ongoing AEs to indicate a resolution or a grade change for clinical trials. Methods: At UAMS, we have implemented a standards-based Adverse Event Reporting...

  11. Efficiencies of Internet-Based Digital and Paper-Based Scientific Surveys and the Estimated Costs and Time for

    Different-sized Cohorts; Constantin E. Uhlig; Berthold Seitz; Nicole Eter; Julia Promesberger; Holger Busse
    Aims: To evaluate the relative efficiencies of five Internet-based digital and three paper-based scientific surveys and to estimate the costs for different-sized cohorts. Methods: Invitations to participate in a survey were distributed via e-mail to employees of two university hospitals (E1 and E2) and to members of a medical association (E3), as a link placed in a special text on the municipal homepage regularly read by the administrative employees of two cities (H1 and H2), and paper-based to workers at an automobile enterprise (P1) and college (P2) and senior (P3) students. The main parameters analyzed included the numbers of invited...

  12. Inequity in India: the case of maternal and reproductive health

    Linda Sanneving; Nadja Trygg; Deepak Saxena; Dileep Mavalankar; Sarah Thomsen
    Background: Millennium Development Goal (MDG) 5 is focused on reducing maternal mortality and achieving universal access to reproductive health care. India has made extensive efforts to achieve MDG 5 and in some regions much progress has been achieved. Progress has been uneven and inequitable however, and many women still lack access to maternal and reproductive health care. Objective: In this review, a framework developed by the Commission on Social Determinants of Health (CSDH) is used to categorize and explain determinants of inequity in maternal and reproductive health in India. Design: A review of peer-reviewed, published literature was conducted using the...

  13. Direct control of paralyzed muscles by cortical neurons

    Chet T. Moritz; Steve I. Perlmutter; Eberhard E. Fetz
    A potential treatment for paralysis resulting from spinal cord injury is to route control signals from the brain around the injury via artificial connections. Such signals could then control electrical stimulation of muscles, thereby restoring volitional movement to paralyzed limbs1–3. In previously separate experiments, activity of motor cortex neurons related to actual or imagined movements has been used to control computer cursors and robotic arms4–10, and paralyzed muscles have been activated by functional electrical stimulation (FES)11–13. Here we show that monkeys can directly control stimulation of muscles using the activity of neurons in motor cortex, thereby restoring goal-directed movements to...

  14. Layer-Resolved Evolution of Organic Thin Films Monitored by Photoelectron Emission Microscopy and Optical Reflectance Spectroscopy

    Ebrahim Ghanbari; Thorsten Wagner
    ABSTRACT: Photoelectron emission microscopy (PEEM) and differential (optical) reflectance spectroscopy (DRS) have proven independently to be versatile analytical tools for monitoring the evolution of organic thin films during growth. In this paper, we present the first experiment in which both techniques have been applied simultaneously and synchronously. We illustrate how the combined PEEM and DRS results can be correlated to obtain an extended perspective on the electronic and optical properties of a molecular film dependent on the film thickness and morphology. As an example, we studied the deposition of the organic molecule α-sexithiophene on Ag(111) in the thickness range from...

  15. RESEARCH Accuracy of electronic ape i e at


    Full list of author information is available at the end of the articleor preparation for post space are not unusual [1,2]. Root perforations compromise the success of endodontic ther-apy and have been regarded as, and probably are still, one of the most unpleasant accidents to deal with during re-treatment [3,4]. Occasionally, a clinician will be chal-lenged with the fact that a radiological diagnose of pa-tient with non-acute clinical symptomatology shows that opening in the tooth crown or root area creating a com-munication between the root canal system with the peri-odontal tissues or oral cavity [5]. Iatrogenic root perforations are frequently...

  16. Providing Contemporary Access to Historical Biospecimen Collections: Development of the NHLBI Biologic Specimen and Data

    Sean A. Coady; Elizabeth L. Wagner
    (NIH), established a Biorepository in 1976 that initially archived biospecimens from population-based blood product safety surveys. It was later expanded to biospecimens from clinical and epidemiological studies in heart, lung, and blood disorders. The NHLBI also established a Data Repository in 2000 to store and distribute study data from NHLBI-sponsored research. The NHLBI Biologic Specimen and Data Repository Information Co-ordinating Center (BioLINCC) was established in 2008 to develop the infrastructure needed to link the contents of these two related NHLBI Repositories, facilitate access to repository resources, and streamline request processes. Three key program subcomponents were developed simultaneously: 1) the linkage...

  17. $rec.titulo


    The Millennial Generation, also known as Generation Y, is the demographic cohort following Generation X, and is generally regarded to be composed of those individuals born between 1980 and 2000. They are the first to grow up in an environment where health-related infor-mation is widely available by internet, TV and other electronic media, yet we know very little about the scope of their health knowledge. This study was undertaken to quantify two domains of clinically relevant health knowledge: factual content and ability to solve health related questions (application) in nine clinically related medical areas. Study subjects correctly answered, on average,...

  18. Poster Sessions Abstract P079 Determinants of HIV outpatient service utilization according to HIV parameters

    Marco Vitale
    Introduction: The increased life expectancy of HIV patients in the era of highly active antiretroviral therapy has had profound consequences for the healthcare systems that provide their care. It is useful to assess whether healthcare resources need to be adapted to the different stages of HIV infection or to patient characteristics [1]. To study how patient features influence utilization of out patient services, we retrospectively analyzed the electronic health record of HIV-positive patients who had followed day-care programs at the AIDS Center of the University of Palermo, Italy.

  19. STUDY PROTOCOL Open Access

    Cristina Hernández-rodríguez; Antonio Fuentes-peláez; Dolores Reina-rodríguez; Rosa De León-gallo; Leonardo Mendez-boo; Pere Torán-monserrat
    Can an alert in primary care electronic medical records increase participation in a population-based screening programme for Methods/Design: This is a parallel randomised trial with a cross-sectional second stage. Participants: all the invited Guiriguet-Capdevila et al. BMC Cancer 2014, 14:232

  20. 2Biomedical Statistics and

    Mark A Frye; Walter A Rocca; Biomedical Informatics; Dr William V Bobo
    An electronic health record driven algorithm to identify incident antidepressant medication users

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