Mostrando recursos 1 - 20 de 37.480

  1. La lengua de signos: aspectos traslativos y sociolingüísticos desde un observatorio italiano

    Gambini, Dianella; Fontana, Sabina
    El propósito de este artículo es mostrar cómo la figura del intérprete de lengua de signos (LS) y la interpretación lengua vocal (LV) ↔ lengua de signos (LS) han evolucionado en la época contemporánea sobre la base de dos factores: 1) el cambio de la situación sociocultural y sociolingüística de la comunidad sorda debido al reconocimiento de la lingüisticidad de la LS y a la dignidad y prestigio que la misma ha adquirido penetrando en contextos antes inaccesibles, gracias a la labor de los intérpretes; 2) las teorías lingüístico-traductivas de la segunda mitad del siglo XX que han demolido la aproximación...

  2. Estudo comparativo das propriedades e da microestrutura do aço DIN 42 CrMo4 MOD temperado em óleo mineral e em solução de polialquileno glicol para aplicação em fixadores de torres eólicas

    Sant'Anna, Rochele Martins
    Energias renováveis fazem parte dos principais debates ao redor do mundo, dentre essas energias destaca-se no Brasil a energia eólica. Contudo o que muitas vezes inviabiliza seu uso são os custos dos materiais, geralmente importados. Para tanto, uma siderúrgica local desenvolveu um aço nacional a fim de substituir os aços importados utilizados na produção de fixadores das torres eólicas, uma variação do aço DIN 42CrMo4, o qual deve atender uma série de exigências quanto às suas propriedades- principalmente dureza, tração e fragilização em temperaturas negativas- para que a segurança e a qualidade das peças sejam garantidas. Este trabalho visa o...

  3. Segregação de índio em cristais Ga1-xInxSb dopados com telúrio obtidos pelo método Bridgman vertical

    Klein, Cândida Cristina
    Os compostos semicondutores ternários, dentre eles o Ga1-xInxSb, têm sido objeto de interesse de pesquisadores e da indústria microeletrônica devido à possibilidade de ajuste da constante de rede, assim como a correspondente modificação da banda proibida de energia e do intervalo de emissão e absorção óptica, com a variação da fração molar de x. A flexibilidade destas propriedades estruturais torna este composto apropriado como substratos para epitaxias de outros compostos ternários e quaternários, na formação de mono e heterojunções. A maneira mais econômica para obtenção de substratos de materiais semicondutores é através do crescimento de cristais a partir da fase...

  4. ISCEV standard for clinical visual evoked potentials: (2016 update).

    Odom, JV; Bach, M; Brigell, M; Holder, GE; McCulloch, DL; Mizota, A; Tormene, AP; International Society for Clinical Electrophysiology of Vision,
    Visual evoked potentials (VEPs) can provide important diagnostic information regarding the functional integrity of the visual system. This document updates the ISCEV standard for clinical VEP testing and supersedes the 2009 standard. The main changes in this revision are the acknowledgment that pattern stimuli can be produced using a variety of technologies with an emphasis on the need for manufacturers to ensure that there is no luminance change during pattern reversal or pattern onset/offset. The document is also edited to bring the VEP standard into closer harmony with other ISCEV standards. The ISCEV standard VEP is based on a subset...

  5. Automatic quantitative analysis of experimental primary and secondary retinal neurodegeneration: implications for optic neuropathies

    Davis, BM; Guo, L; Brenton, J; Langley, L; Normando, EM; Cordeiro, MF
    Secondary neurodegeneration is thought to play an important role in the pathology of neurodegenerative disease, which potential therapies may target. However, the quantitative assessment of the degree of secondary neurodegeneration is difficult. The present study describes a novel algorithm from which estimates of primary and secondary degeneration are computed using well-established rodent models of partial optic nerve transection (pONT) and ocular hypertension (OHT). Brn3-labelled retinal ganglion cells (RGCs) were identified in whole-retinal mounts from which RGC density, nearest neighbour distances and regularity indices were determined. The spatial distribution and rate of RGC loss were assessed and the percentage of primary...

  6. Meyer's loop asymmetry and language lateralisation in epilepsy

    Nowell, M; Vos, SB; Sidhu, M; Wilcoxen, K; Sargsyan, N; Ourselin, S; Duncan, JS
    OBJECTIVES: Several studies have suggested an asymmetry in Meyer's loop in individuals, with the left loop anterior to the right. In this study we test the hypothesis that there is an association between Meyer's loop asymmetry (MLA) and language lateralisation. METHODS: 57 patients with epilepsy were identified with language functional MRI (fMRI) and diffusion MRI acquisition. Language lateralisation indices from fMRI(LI) and optic radiation and arcuate fasciculus probabilistic tractography was performed for each subject. The subjects were divided into left language dominant (LI>0.4) and non-left language groups (LI<0.4) according to their LI. RESULTS: A negative linear correlation was identified between...

  7. $rec.titulo


    Aniridia (OMIM 106210) is a congenital panocular disorder characterized by complete or partial absence of the iris. In most cases, aniridia is typically accompanied by foveal hypoplasia with impaired visual acuity and nystagmus [1,2]. Other sight-threatening complications, which may or may not be present, include corneal abnormalities, cataract, lens subluxation, glaucoma, strabismus, and optic nerve hypoplasia [2]. Heterozygous mutations in paired box gene 6 (PAX6, OMIM 607108) are primarily responsible for aniridia [3-8]. About two-thirds of aniridia cases are familial, in which they are transmitted as an autosomal dominant trait with complete penetrance and variable expressivity; the remainder are sporadic...

  8. e


    (OMIM 606580) have been reported in ADOA Denmark Full list of author information is available at the end of the articleBackground Autosomal dominant optic atrophy (ADOA) is charac-terized by bilateral visual loss, preferential temporal disk pallor, dyschromatopsia, relative or absolute centrocoe-calscotoma, and subnormal thickness of the retinal gan-glion cell and nerve-fiber layers. The disease has incomplete penetrance and variable expressivity, ranging from subclinical visual dysfunction to legal blindness. The highly variable phenotype, both within and between families, suggests that modifier genes and/or environ-mental factors influence the expression of the disease. The prevalence of 1:12,000 in Denmark is remarkably high compared...

  9. Diagnosis and Management of a Bilateral Macular Problem

    Case Presentation; Alireza Ramezani
    A 59‑year‑old gentleman presented with decreased visual acuity and metamorphopsia in both eyes for one year, worsening over the past three months. Except for a history of phacoemulsification and intraocular lens (IOL) implantation in his left eye, medical, surgical and ocular history was unremarkable. Best corrected visual acuity was 3/10 and 6/10 with +3.50‑0.75 × 180 and −0.50‑0.75 × 180 in the right and left eyes, respectively. There was no relative afferent pupillary defect. Slit lamp examination revealed 2 + nuclear sclerosis (NS) and 2 + posterior subcapsular (PSC) cataract in the right eye and a well‑positioned posterior chamber IOL...

  10. Open Access Abnormalities of Fundus Autofluorescence in Pigmented Paravenous Chorioretinal Atrophy

    Yuki Hashimoto; Satoru Kase
    Abstract: The aim of this study is to investigate fundus autofluorescence (FAF) as well as fluorescein angiography (FA), indocyanine green angiography (IA), and optical coherence tomography (OCT) in a patient with pigmented paravenous chorioretinal atrophy (PPCRA). A funduscopic examination revealed chorioretinal atrophy along the paravenous area in both eyes. A marked bone spicule pigment clumping together with the atrophy was noted left eye. FA and IA showed a window defect and hypofluorescence, respectively, which exclusively corresponds to the atrophic area along the retinal vein area and the optic disc both eyes. FAF revealed geographic hypofluorescence along the paravenous and supranasal...

  11. Clinical Study Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome


    Copyright © 2013 Mehmet Demir et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Aim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion cell complex (GCC) thicknesses were measured by optical coherence tomography (OCT). In addition,...

  12. Motivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice

    David F. Wozniak; Kelly A. Diggs-andrews; Sara Conyers; Carla M. Yuede; Joshua T. Dearborn; Jacquelyn A. Brown; Kazuhiro Tokuda; Yukitoshi Izumi; Charles F. Zorumski; David H. Gutmann
    Children with neurofibromatosis type 1 (NF1) frequently have cognitive and behavioral deficits. Some of these deficits have been successfully modeled in Nf1 genetically-engineered mice that develop optic gliomas (Nf1 OPG mice). In the current study, we show that abnormal motivational influences affect the behavior of Nf1 OPG mice, particularly with regard to their response to novel environmental stimuli. For example, Nf1 OPG mice made fewer spontaneous alternations in a Y-maze and fewer arm entries relative to WT controls. However, analysis of normalized alternation data demonstrated that these differences were not due to a spatial working memory deficit. Other reported behavioral...

  13. Comparison of Optic Disc Morphology of Optic Nerve Atrophy between Compressive Optic Neuropathy and Glaucomatous Optic Neuropathy

    Masayuki Hata; Kazuaki Miyamoto; Akio Oishi; Yukiko Makiyama; Norimoto Gotoh; Yugo Kimura; Tadamichi Akagi; Nagahisa Yoshimura
    Objectives: To compare the optic nerve head (ONH) structure between compressive optic neuropathy (CON) and glaucomatous optic neuropathy (GON), and to determine whether selected ONH quantitative parameters effectively discriminate between GON and CON, especially CON cases presenting with a glaucoma-like disc. Methods: We prospectively assessed 34 patients with CON, 34 age-matched patients with moderate or severe GON, and 34 age-matched healthy control subjects. The quantitative parameters of ONH structure were compared using the Heidelberg Retina Tomograph 2 (HRT2) and Spectralis optical coherence tomography with an enhanced depth imaging method. Results: The mean and maximum cup depths of CON were significantly...

  14. A Female Patient with Down Syndrome and Low-Penetrance Leber’s Hereditary Optic Neuropathy

    Starleen E. Frousiakis; Starleen E. Frousiakisa; Andrew E. Pouwa; Rustum Karanjiab; Alfredo A. Sadunb; Doheny Eye Centres
    the online version of the article only. Distribution permitted for non-commercial purposes only.

  15. Dynamic acousto-optic control of a strongly coupled photonic molecule

    Stephan Kapfinger; Thorsten Reichert; Stefan Lichtmannecker; Jonathan J. Finley; Achim Wixforth; Michael Kaniber; Hubert J. Krenner
    Strongly confined photonic modes can couple to quantum emitters and mechanical excita-tions. To harness the full potential in quantum photonic circuits, interactions between dif-ferent constituents have to be precisely and dynamically controlled. Here, a prototypical coupled element, a photonic molecule defined in a photonic crystal membrane, is controlled by a radio frequency surface acoustic wave. The sound wave is tailored to deliberately switch on and off the bond of the photonic molecule on sub-nanosecond timescales. In time-resolved experiments, the acousto-optically controllable coupling is directly observed as clear anticrossings between the two nanophotonic modes. The coupling strength is determined directly from...

  16. Calciphylaxis: Temporal Artery Calcification Preceding Widespread Skin Lesions and Penile Necrosis

    Article Id; Manzoor A. Shah
    Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Temporal artery calciphylaxis has rarely been described in chronic kidney disease patients on dialysis. We report a case of 72-year-old Caucasian man with multiple comorbidities and end-stage renal disease on dialysis who presented with temporal artery calcification leading to bilateral loss of vision followed by extensive skin lesions including one on glans penis. While on peritoneal dialysis, he developed anterior ischemic optic neuropathy, had no improvement on high dose steroids, and temporal artery biopsy showed marked calcification without any evidence of...

  17. Spectrum Disorder following

    Richard Heekin; Seronegative Neuromyelitis Optica; Exposure Hepatitis; B Vaccination; Richard Heekin; Chetan Gandhy; Derrick Robertson; Key Words
    www.karger.com/crn

  18. Correspondence to:


    Universally, it is an estimation that 60 million individuals with glaucomatous optic neuropathy. In addition, there are an estimated 8.4 million glaucomatous patients who are blind. These patients are expected to increase to 80 million and 11.2 million by the year 2020. Statistically, glaucoma has been considered as the second leading cause of blindness in the world [1]. The universal definition of glaucoma is that it is an optic neuropathy with assorted etiology, which disturbs the optic nerve head, thereby resulting in visual loss and permanent impairment of visual function [2]. On the other hand, primary open angle glaucoma is...

  19. GLAUCOMA


    Three-dimensional optic nerve head images using optical coherence tomography with a broad bandwidth, femtosecond, and mode-locked laser

  20. $rec.titulo


    perience with a MAS patient with acromegaly who has been fol-lowed 3 years and adequately managed by decompression of op-tic nerve and near-total transsphenoidal resection. CASE REPORT First clinical manifestation A 19-year-old man first visited our medical center when he was 16-years-old because of intermittent headache, dizziness and left eye visual disturbance. He had been assessed using magnet-ic resonance image (MRI) and electroencephalography (EEG) for these symptoms at a regional hospital. There was no abnormal finding in EEG but MR imaging showed mucoperiosteal thick-ening in the left maxillary sinus expanded bone in the left fron-tal, temporal calvarium and body of...

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