Mostrando recursos 81 - 100 de 5.408

  1. $rec.titulo

    Naso, Aurore

  2. Rabies viral mechanisms to escape the IFN system: the viral protein P interferes with IRF-3, Stat1, and PML nuclear bodies.

    Chelbi-Alix, Mounira K; Vidy, Aurore; El Bougrini, Jamila; Blondel, Danielle
    Interferons (IFNs) are a family of secreted proteins with antiviral, antiproliferative, and immunomodulatory activities. The different biologic actions of IFN are believed to be mediated by the products of specifically IFN-stimulated genes (ISG) in the target cells. The IFN response is the first line of defense against viral infections. Viruses, which require the cellular machinery for their replication, have evolved different ways to counteract the action of IFN by inhibiting IFN production or Jak-Stat signaling or by altering ISG products. This review focuses on the role of viral proteins from the RNA virus family, particularly rabies P protein. P protein...

  3. A multidisciplinary study on the Carboniferous (Namurian) Montmarault granitic pluton and its tectonic bearings on the activity of the Sillon Houiller Fault (Variscan Massif Central, France)

    Joly, Aurore; Chen, Yan; Faure, Michel; Martelet, Guillaume; Truffert, Catherine
    In the Variscan French Massif Central, the Sillon Houiller Fault (SHF) is a major sub meridian discontinuity which kinematics, timing and evolution remain poorly understood. The spatial relationship of this accident with the surrounding granitic plutons suggests a genetic link between the SHF activity and pluton emplacement. The SHF is classically interpreted as a Late Carboniferous left-lateral wrench fault that might have accommodated a NW-SE and NE-SW extensional tectonics to theWest and East, respectively. However, this model disagrees with structural and geochronologic data that clearly show two successive and distinct extensional strain fields. Thus, in order to better understand the...

  4. Insights in the ductile history of the northern Sillon Houiller Fault via a multidisciplinary study of the Late Variscan Montmarault pluton (French Massif Central).

    Joly, Aurore; Chen, Yan; Faure, Michel; Martelet, Guillaume
    In order to better understand the role of the lithosphere-scale Sillon Houiller Fault (SHF) during the Late Variscan evolution of the Massif Central, a multidisciplinary study has been carried out on the Montmarault massif: petrology, geochronology, Anisotropy of Magnetic Susceptibility (AMS), gravity as well as interpretation of aeromagnetic survey. Based on rock density and magnetic susceptibility measurements, a direct 2D joint gravity and magnetic modelling has been performed along several cross sections. Then, the new geophysical, field and AMS structural information, have been integrated into a 3D geological model which highlights the geometry, the emplacement of Montmarault pluton and its...

  5. Coupling 3D modelling and forward-inverse modelling of potential field data (gravity and magnetic data).

    Joly, Aurore; Guillen, Antonio; Calcagno, Philippe; Courrioux, Gabriel
    The 3D modeling of geological objects is often decomposed in two steps: i) delimitation of the boundaries of the units corresponding to the various geological formations or ore types; and ii) verification and estimation of these boundaries using geophysical data. A new approach using potential-field interpolators addressing the 3D modeling problem is used here (Ch.Lajaunie et al. 1997). We will discuss how we can statistically estimate the validity of such 3D model taking in account various geophysical data. This estimation can be computed by inverting complementary datasets, provided (a) the data are a function of the 3D distribution of a...

  6. TReX: A Tool for Reachability Analysis of Complex Systems

    Collomb-Annichini, Aurore; Bouajjani, Ahmed; Sighireanu, Mihaela
    The paper describe a tool, called TReX, allowing to analyse automatically automata-based models equipped with variables of different kinds of infinitedomain data structures and with parameters (i.e., uninstantiated constants). These models are, at the present time, parametric (continuous-time) timed automata, extended with integer counters and communicating through unbounded lossy FIFO queues. The techniques used in TReX are based on symbolic reachability analysis. Symbolic representation structures are used to represent infinite sets of configurations, and forward/backward exploration procedures are used to generate a symbolic reachability graph. The termination is not guaranteed, but efficient extrapolation techniques are used to help it. These...

  7. DNA methylation promotes Aurora-B-driven phosphorylation of histone H3 in chromosomal subdomains

    Monier, Karine; Mouradian, Sandrine; Sullivan, Kevin
    International audience

  8. $rec.titulo

    Joly, Aurore

  9. A multidisciplinary study of a syntectonic pluton close to a major lithospheric-scale fault: relationships between the Montmarault granitic massif and the Sillon Houiller Fault in the Variscan French Massif Central. Part II: Gravity, aeromagnetic investigations and 3D geologic modeling.

    Joly, Aurore; Martelet, Guillaume; Chen, Yan; Faure, Michel
    International audience

  10. The nucleocytoplasmic rabies virus P protein counteracts interferon signaling by inhibiting both nuclear accumulation and DNA binding of STAT1.

    Vidy, Aurore; El Bougrini, Jamila; Chelbi-Alix, Mounira,; Blondel, Danielle
    International audience

  11. Efficient hepatocyte engraftment in a nonhuman primate model after partial portal vein embolization.

    Dagher, Ibrahim; Boudechiche, Lyes; Branger, Julie; Coulomb-Lhermine, Aurore; Parouchev, Alexandre; Hadchouel, Michelle; Pariente, Danièle; Andreoletti, Marion; Franco, Dominique; Weber, Anne
    International audience

  12. Efficient hepatocyte engraftment in a nonhuman primate model after partial portal vein embolization.

    Dagher, Ibrahim; Boudechiche, Lyes; Branger, Julie; Coulomb-Lhermine, Aurore; Parouchev, Alexandre; Hadchouel, Michelle; Pariente, Danièle; Andreoletti, Marion; Franco, Dominique; Weber, Anne
    International audience

  13. Primate hepatic foetal progenitor cells and their therapeutic potential.

    Weber, Anne; Delgado, Jean-Paul; Parouchev, Alexandre; Branger, Julie; Mainot, Sylvie; Coulomb, Aurore; Mahieu, Dominique
    International audience

  14. Dark current analysis of Quantum Cascade Detectors by Magneto-Resistance measurements

    Gomez, Aurore; Péré-Laperne, Nicolas; De Vaulchier, Louis-Anne; Koeniguer, Cédric; Vasanelli, Angela; Nedelcu, Alexandru; Marcadet, Xavier; Guldner, Yves; Berger, Vincent
    International audience

  15. Barrier Breakdown in a Multiple Quantum Well Structure

    Gomez, Aurore; Berger, Vincent; Péré-Laperne, Nicolas; De Vaulchier, Louis-Anne
    International audience

  16. Les figures du projet territorial

    Debarbieux, Bernard; Lardon, Sylvie
    Aujourd'hui les projets de territoire, comme les journaux et les télévisions, sont pleins d'images, de cartes, de graphiques. Il ne faut pas s'en plaindre : l'iconographie est un puissant moyen d'expression et l'éventail de plus en plus large de ses outils de représentation constitue une aubaine pour tous ceux qui veulent donner à voir, préfigurer ou simplement penser ensemble un territoire. Toutefois, à y regarder de près, on acquiert vite le sentiment que le recours à la figure relève majoritairement de démarches empiriques et intuitives. Aussi cet ouvrage propose-t-il un panorama des analyses existantes sur le rôle des images -...

  17. Les sépultures chasséennes du lotissement La Terrasse à Villeneuve Tolosane

    Vaquer, Jean; Duday, Henri; Schmitt, Aurore; Gandelin, Muriel; Gleize, Yves; Giraud, Jean Pierre

  18. $rec.titulo

    Panagiotis, Lainas; Boudechiche, Lyes; Osorio, Angel; Coulomb, Aurore; Weber, Anne; Pariente, Danièle; Franco, Dominique; Dagher, Ibrahim
    International audience

  19. $rec.titulo

    Panagiotis, Lainas; Boudechiche, Lyes; Osorio, Angel; Coulomb, Aurore; Weber, Anne; Pariente, Danièle; Franco, Dominique; Dagher, Ibrahim
    International audience

  20. In vivo imaging of transplanted hepatocytes with a 1.5-T clinical MRI system--initial experience in mice.

    Luciani, Alain; Parouchev, Alexandre; Smirnov, Pierre; Braga, Gustavo; Wilhelm, Claire; Gazeau, Florence; Boudechiche, Lyes; L'Hermine-Coulomb, Aurore; Dagher, Ibrahim; Franco, Dominique; Rahmouni, Alain; Hadchouel, Michèle; Weber, Anne; Clement, Olivier
    International audience

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