Mostrando recursos 1 - 20 de 168

  1. $rec.titulo

    Jiménez Mejías, E.; Departamento de Medicina Preventiva y Salud Pública. Universidad de Granada; Lardelli Claret, P.; Departamento de Medicina Preventiva y Salud Pública. Universidad de Granada; Amezcua Prieto, C.; Departamento de Medicina Preventiva y Salud Pública. Universidad de Granada; Jiménez Moleón, J.J.; Departamento de Medicina Preventiva y Salud Pública. Universidad de Granada

  2. A multilevel integrated approach for the identification of predictive markers of metabolic syndrome

    Pujos-Guillot, Estelle; Bertrand, Julien; Rambeau, Mathieu; Petera, Mélanie; Brandolini-Bunlon, Marion; Fernandes, Anthony; Matta, Joanne; Lévy-Marchal, Claire; Czernichow, Sébastien; Comte, Blandine
    the COST action in Open Multiscale Systems Medicine (OpenMultiMed), E-COST CA15120The meeting was followed by a joint session at the European Association for Predictive, Preventive & Personalized Medicine (EPMA) Congress on Friday, 15 September

  3. A multilevel integrated approach for the identification of predictive markers of metabolic syndrome

    Pujos-Guillot, Estelle; Bertrand, Julien; Rambeau, Mathieu; Petera, Mélanie; Brandolini-Bunlon, Marion; Fernandes, Anthony; Matta, Joanne; Lévy-Marchal, Claire; Czernichow, Sébastien; Comte, Blandine
    the COST action in Open Multiscale Systems Medicine (OpenMultiMed), E-COST CA15120The meeting was followed by a joint session at the European Association for Predictive, Preventive & Personalized Medicine (EPMA) Congress on Friday, 15 September

  4. A multilevel integrated approach for the identification of predictive markers of metabolic syndrome

    Pujos-Guillot, Estelle; Bertrand, Julien; Rambeau, Mathieu; Petera, Mélanie; Brandolini-Bunlon, Marion; Fernandes, Anthony; Matta, Joanne; Lévy-Marchal, Claire; Czernichow, Sébastien; Comte, Blandine
    the COST action in Open Multiscale Systems Medicine (OpenMultiMed), E-COST CA15120The meeting was followed by a joint session at the European Association for Predictive, Preventive & Personalized Medicine (EPMA) Congress on Friday, 15 September

  5. Modeling bovine viral diarrhea virus (BVDV) spread between dairy cattle farms ar a regional scale: relative contribution of two between-herd transmission pathways

    Qi, Luyuan; Vergu, Elisabeta; Dutta, Bhagat Lal; Ezanno, Pauline
    Modeling bovine viral diarrhea virus (BVDV) spread between dairy cattle farms ar a regional scale: relative contribution of two between-herd transmission pathways. Society for Veterinary Epidemiology and Preventive Medicine (SVEPM)

  6. $rec.titulo

    Hernández-García, Ignacio; Servicio de Medicina Preventiva. Hospital General Universitario de Alicante.; Sáenz-González, María del Carmen; Servicio de Medicina Preventiva y Salud Pública. Hospital Universitario de Salamanca.; González-Celador, Rafael; Servicio de Medicina Preventiva y Salud Pública. Hospital Universitario de Salamanca.

  7. New aspects on the regulation of the methionine cycle in liver injury

    Pajares, María A.
    Resumen del trabajo presentado a la 3rd International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics, celebrada en valencia (España) del 1 al 3 de septiembre de 2015.

  8. Plectin is a novel regulator for apical extrusion of RasV12-transformed cells

    Kadeer, Ailijiang; Maruyama, Takeshi; Kajita, Mihoko; Morita, Tomoko; Sasaki, Ayana; Ohoka, Atsuko; Ishikawa, Susumu; Ikegawa, Masaya; Shimada, Takashi; Fujita, Yasuyuki
    Several lines of evidence have revealed that newly emerging transformed cells are often eliminated from the epithelium, though the underlying molecular mechanisms of this cancer preventive phenomenon still remain elusive. In this study, using mammalian cell culture systems we have identified plectin, a versatile cytoskeletal linker protein, as a novel regulator for apical extrusion of RasV12-transformed cells. Plectin is accumulated in RasV12 cells when they are surrounded by normal epithelial cells. Similarly, cytoskeletal proteins tubulin, keratin, and Epithelial Protein Lost In Neoplasm (EPLIN) are also accumulated in the transformed cells surrounded by normal cells. Knockdown or functional disruption of one...

  9. The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia

    Yamauchi, Hajime; Matsumaru, Takanori; Morita, Tomoko; Ishikawa, Susumu; Maenaka, Katsumi; Takigawa, Ichigaku; Semba, Kentaro; Kon, Shunsuke; Fujita, Yasuyuki
    Recent studies have revealed that cell competition can occur between normal and transformed epithelial cells; normal epithelial cells recognize the presence of the neighboring transformed cells and actively eliminate them from epithelial tissues. Here, we have established a brand-new high-throughput screening platform that targets cell competition. By using this platform, we have identified Rebeccamycin as a hit compound that specifically promotes elimination of RasV12-transformed cells from the epithelium, though after longer treatment it shows substantial cytotoxic effect against normal epithelial cells. Among several Rebeccamycin-derivative compounds, we have found that VC1-8 has least cytotoxicity against normal cells but shows the comparable...

  10. International regulatory landscape and integration of corrective genome editing into in vitro fertilization

    Araki, Motoko; Ishii, Tetsuya
    Genome editing technology, including zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat (CRISPR)/Cas, has enabled far more efficient genetic engineering even in non-human primates. This biotechnology is more likely to develop into medicine for preventing a genetic disease if corrective genome editing is integrated into assisted reproductive technology, represented by in vitro fertilization. Although rapid advances in genome editing are expected to make germline gene correction feasible in a clinical setting, there are many issues that still need to be addressed before this could occur. We herein examine current status of genome...

  11. Hockey fans in training: a pilot pragmatic randomized controlled trial

    Petrella, Robert J.; Gill, Dawn P.; Zou, Guangyong; De Cruz, Ashleigh; Riggin, Brendan; Bartol, Cassandra; Danylchuk, Karen; Hunt, Kate; Wyke, Sally; Gray, Cindy M.; Bunn, Christopher; Zwarenstein, Merrick
    Introduction: Hockey Fans in Training (Hockey FIT) is a gender-sensitized weight loss and healthy lifestyle program. We investigated: 1) feasibility of recruiting and retaining overweight and obese men into a pilot pragmatic randomized controlled trial; and 2) potential for Hockey FIT to lead to weight loss and improvements in other outcomes at 12 weeks and 12 months. Methods: Male fans of 2 ice hockey teams (35-65 years; body-mass index ≥28 kg/m2) located in Ontario (Canada) were randomized to intervention (Hockey FIT) or comparator (Wait-list Control). Hockey FIT includes a 12-week active phase (weekly, coach-led group meetings including provision of dietary information,...

  12. ¡Al pueblo! -- : consejos higiénicos y remedios preventivos contra el cólera-morbo-asiático, con el modo de disminuir sus estragos y combatir los primeros síntomas hasta la llegada del médico

    Díaz Benito y Angulo, José, 1824-1890
    [¡Al pueblo!]

  13. El imaginario social de los profesores de la Institución Educativa Villa Elisa, sede B, frente a la actividad física

    Rincón Espitia, Edwin Danilo
    Durante los últimos años, han estado resurgiendo las relaciones entre la actividad física y la salud. Dicho resurgimiento ha sido motivado, en gran medida, por el incremento de los casos de enfermedades cardiovasculares. Tal incremento, además, ha impulsado el apoyo recibido por la medicina preventiva, la cual, tiene por objetivo reducir los costos de la medicina tradicional curativa. Para ello, la medicina preventiva se vale de la extensión de un concepto más abierto y dinámico de lo que es la salud, enfocándose en la creación y promoción de ambientes y estilos de vida saludables con el propósito de formar en las personas la denominada “consciencia social de...

  14. Active pause and fitness

    Osorio Hortua, Jerson Asis
    Actualmente se hace cada vez más énfasis en la medicina preventiva en donde la prevención primaria juega un papel esencial y se traduce en, mejoría de la calidad de vida y disminución de los costos en salud. Un trabajador se encuentra sometido a una serie de riesgos laborales como estrés, fatiga, desmotivación, patologías derivadas de las lesiones músculo esqueléticas, provocados por los esfuerzos repetitivos y aumentos de la carga de trabajo, lo que produce una disminución en la productividad empresarial, donde cabe citar un estudio realizado por el Ministerio de la Protección Socia (2006) donde se refleja que en Colombia,...

  15. Aarhus Regenerative Orthopaedics Symposium (AROS): Regeneration in the ageing population

    Foldager, Casper B; Bendtsen, Michael; Berg, Lise C; Brinchmann, Jan E; Brittberg, Mats; Bunger, Cody; Canseco, Jose; Chen, Li; Christensen, Bjørn B; Colombier, Pauline; Deleuran, Bent W; Edwards, James; Elmengaard, Brian; Farr, Jack; Gatenholm, Birgitta; Gomoll, Andreas H; Hui, James H; Jakobsen, Rune B; Joergensen, Natasja L; Kassem, Moustapha; Koch, Thomas; Kold, Søren; Krogsgaard, Michael R; Lauridsen, Henrik; Le, Dang; Le Visage, Catherine; Lind, Martin; Nygaard, Jens V; Olesen, Morten L; Pedersen, Michael; Rathcke, Martin; Richardson, James B; Roberts, Sally; Rölfing, Jan H D; Sakai, Daisuke; Toh, Wei Seong; Urban, Jill; Spector, Myron
    The combination of modern interventional and preventive medicine has led to an epidemic of ageing. While this phenomenon is a positive consequence of an improved lifestyle and achievements in a society, the longer life expectancy is often accompanied by decline in quality of life due to musculoskeletal pain and disability. The Aarhus Regenerative Orthopaedics Symposium (AROS) 2015 was motivated by the need to address regenerative challenges in an ageing population by engaging clinicians, basic scientists, and engineers. In this position paper, we review our contemporary understanding of societal, patient-related, and basic science-related challenges in order to provide a reasoned roadmap...

  16. Healthcare and Medical IoT

    Datta, Shoumen
    Detection of analytes in the context of nano-diagnostics for preventive medicine and global public health.

  17. Healthcare and Medical IoT

    Datta, Shoumen
    Detection of analytes in the context of nano-diagnostics for preventive medicine and global public health.

  18. Healthcare and Medical IoT

    Datta, Shoumen
    Detection of analytes in the context of nano-diagnostics for preventive medicine and global public health.

  19. Healthcare and Medical IoT

    Datta, Shoumen
    Detection of analytes in the context of nano-diagnostics for preventive medicine and global public health.

  20. Healthcare and Medical IoT

    Datta, Shoumen
    Detection of analytes in the context of nano-diagnostics for preventive medicine and global public health.

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